Pediatric

Perfusfind S.L.

Abstract Background Bleeding and thrombosis are common extracorporeal membrane oxygenation (ECMO) complications associated with increased mortality. Heparin is the most commonly used ECMO anticoagulant, employed in 94% of cases. Reduced antithrombin III (AT3) levels could decrease heparin effectiveness. Neonates have inherently lower levels of AT3 than adults, and pediatric patients..

Perfusfind S.L.

Abstract Children who experience cardiac arrest are one and a half times more likely to survive at a hospital capable of providing the life support system called ECMO, research suggests. But the reason behind better outcomes may have less to do with being saved by the heart and lung support..

Perfusfind S.L.

Abstract BACKGROUND:  Heparin resistance (HR) is a common finding in pediatric cardiac surgery and generally refers to decreased sensitivity to heparin. Antithrombin (AT) deficiency is considered the primary mechanism of HR; however, the etiology of HR may be multifactorial. Early identification of HR might help optimize heparin anticoagulation management. This..

Perfusfind S.L.

Abstract Importance Phthalate chemicals are used to manufacture disposable plastic medical products, including blood storage bags and components of cardiopulmonary bypass (CPB) circuits. During cardiac surgery, patients can be inadvertently exposed to phthalate chemicals that are released from these plastic products. Objective To quantify iatrogenic phthalate chemical exposure in pediatric patients undergoing..

Perfusfind S.L.

Abstract Background: The charity organization Kinderherzen retten e.V. (KHR) enables humanitarian congenital heart surgery for pediatric patients from low- and middle-income countries at the University Heart Center Freiburg, Germany. The aim of this study was to assess periprocedural and mid-term outcomes of these patients for evaluation of KHR sustainability.  Methods: Part one of the..

Perfusfind S.L.

Abstract Cardiopulmonary bypass is an integral and indispensable part of surgical repair of congenital heart defects. While the complications and morbidity secondary to the use of cardiopulmonary bypass has decreased considerably, there remains a significant incidence of clinically relevant renal and neurological injury. To provide more physiological delivery of oxygenated..

Perfusfind S.L.

This case reports on a six month old male patient (weight 6 kg), who presented with agonal respiration and history of acute febrile illness. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2023/08/CoM_08_2023_E_web_compressed-1.pdf" title="CoM_08_2023_E_web_compressed"]  

Perfusfind S.L.

Abstract Objective:  To determine the association of venovenous extracorporeal membrane oxygenation (VV-ECMO) initiation with changes in vasoactive-inotropic scores (VISs) in children with pediatric acute respiratory distress syndrome (PARDS) and cardiovascular instability. Design:  Retrospective cohort study. Setting:  Single academic pediatric ECMO center. Patients:  Children (1 mo to 18 yr) treated with VV-ECMO (2009–2019) for PARDS..

Perfusfind S.L.

Abstract Background: We assessed the impact of the liberalized ABO pediatric policy change on candidate characteristics and outcomes for children undergoing heart transplant (HT). Methods and results: Children <2 years undergoing HT with ABO strategy reported at listing and HT from December 2011 to November 2020 to the Scientific Registry of Transplant..

Perfusfind S.L.

Abstract Objectives Prematurity is a risk factor for in-hospital mortality after cardiac surgery. The structure of  models designed to deliver optimal care to neonates including those born preterm with critical  is unknown. The objective of this study was to evaluate in-hospital outcomes after cardiac surgery across gestational ages in an institution with..