Pediatric

Perfusfind S.L.

Abstract Background Understanding cerebral blood flow regulation and later optimizing brain perfusion is part of neuroprotection during cardiopulmonary bypass (CPB) in neonates. Methods A total of 38 neonates undergoing CPB were monitored using near-infrared spectrometry and mean arterial pressure (MAP). Cerebral autoregulation (CAR) was assessed through the continuous measurement of..

Perfusfind S.L.

Abstract Background Minimally invasive thoracotomies to repair selected congenital heart defects are considered only a cosmetic alternative approach by many; however, they represent the routine alternative in centers of expertise. Methods Pooled institutional data from the European Congenital Heart Surgeons Association using mini-thoracotomy approaches were analyzed since the beginning of..

Perfusfind S.L.

Abstract Background/Objectives: Conventional cardiopulmonary resuscitation (CCPR) has been the foundational resuscitation approach for decades. Where CCPR is unsuccessful, extracorporeal membrane oxygenation-assisted CPR (ECPR) may improve outcomes. Predicting failure of CCPR and immediate need for ECPR is difficult, and data are lacking. In this retrospective analysis, we analysed both factors that..

Perfusfind S.L.

Abstract Managing acute brain injury involves protecting the brain from secondary injury by addressing the mismatch between metabolic demand and cerebral perfusion. Observational studies have associated impaired cerebral autoregulation, a physiological process governing the regulation of cerebral blood flow, with unfavorable neurological outcomes in both pediatric and adult populations. We..

Perfusfind S.L.

Abstract Background: This study aimed to investigate the effect of operative and postoperative parameters on late-onset hyperlactatemia (LOHL) after cardiac surgery in the pediatric patient population.Methods: One hundred fifty-nine ventricular septal defect patients (77 males, 82 females; mean age: 8.0±8.6 years; range, 1 to 48 years) were retrospectively examined between August 2020..

Perfusfind S.L.

Abstract Introduction Sternotomy has been the most common approach for the correction of congenital cardiac defects, and questions arise surrounding the safety, feasibility, and cost-effectiveness of implementing minimally invasive techniques in congenital cardiac surgery, despite their global adoption over the past three decades. Nevertheless, the availability of published data from..

Perfusfind S.L.

Abstract Penetrating cardiac injury in children is a life-threatening emergency. The initial reaction of the witness and medical team management plays a crucial role in survival. We are reporting a five-year-old girl who had a penetrating cardiac injury after an accidental fall on a sharp date tree thorn, witnessed by..

Perfusfind S.L.

Abstract Background Although goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) has been discussed extensively in adult studies, no pediatric indexed oxygen delivery (Do2i) thresholds are universally accepted, and no pediatric randomized controlled trial has been reported. This study aimed to determine whether the GDP initiative (maintaining Do2i ≥360 mL/min/m2 during CPB)..

Perfusfind S.L.

Abstract Nosocomial infections are one of the most frequent complications of extracorporeal membrane oxygenation (ECMO) and are associated with increased mortality (). Bloodstream infections present a particular problem because of the risk of biofilm formation and the clinical challenges associated with cannula and circuit exchanges in this patient population ()...

Perfusfind S.L.

Abstract Background The objective of this study was to evaluate mean cerebral blood flow velocity, gaseous microemboli (GME) counts, regional cerebral oxygen saturation (rSO2), and clinical outcomes using multimodality neuromonitoring in risk-stratified congenital cardiac surgery patients and by cyanotic and acyanotic heart disease. Methods A total of 377 pediatric patients..