Abstract Acute kidney injury is a common and serious complication after congenital heart surgery, particularly among infants. This comorbidity has been independently associated with adverse outcomes including an increase in..
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Abstract Purpose of Review This paper will discuss current cannulation strategies for infant aortic arch repair and compare them to more traditionally used techniques. Recent Findings Aortic arch reconstruction in..
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Abstract Background: The aim of the study was to evaluate the effects of high-dose nitroglycerine administered during cardiopulmonary bypass on the intraoperative cerebral saturation and postoperative serum creatinine concentration in..
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Abstract Malignant hyperthermia is a well-known but potentially lethal disorder which is triggered by volatile anesthetics and depolarizing muscle relaxants. Early diagnosis and treatment could save lives. However, during cardiac..
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Abstract We describe a quality improvement initiative aimed at achieving interdisciplinary consensus about the appropriate delivery of extracorporeal membrane oxygenation (ECMO). Interdisciplinary rounds were implemented for all patients on ECMO..
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Abstract Objective: To describe neurobehavioral outcomes and investigate factors associated with survival and survival with good neurobehavioral outcome 1 year after in-hospital cardiac arrest for children who received extracorporeal cardiopulmonary..
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Abstract Aim Although recent (CA) trials found no benefits of versus normothermia , preclinical models suggest earlier timing of hypothermia improves efficacy. This study investigated whether shorter time to goal temperature was associated with..
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Abstract Objective To determine whether a continuous of standard amino acids could preserve kidney function after on-pump cardiac surgery. Methods Adult patients scheduled to receive cardiac surgery lasting longer than 1 hour..
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Abstract Background There is an increasing number of young adults living with (CHD). The goal of this study was to ascertain the frequency of (AKI) as well as the risk factors and..
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Abstract Essentials Strategies to improve platelet function may reduce excessive bleeding during cardiac surgery. Patients were randomized to standard care or standard care + noradrenaline infusion. Low‐dose noradrenaline improved intraoperative..
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Abstract Perfusion strategies for have direct consequences on pediatric cardiac surgery outcomes. However, inconsistent study results and a lack of uniform evidence-based guidelines for pediatric cardiopulmonary bypass management have led to..
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Abstract Background During cold storage, some red blood cell (RBC) units age more rapidly than others. Yet, the Food and Drug Administration has set a uniform storage limit of 42..
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Abstract Background and Aim of the Study Extracorporeal life support (ECLS) may be necessary in refractory postcardiotomy cardiogenic shock (PCS) unresponsive to optimal medical treatment. We sought to analyze the..
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Abstract Central venoarterial extracorporeal membrane oxygenation has been used since the 1970s to support patients with cardiogenic shock following cardiac surgery. Despite this, in-hospital mortality is still high, and although..
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Abstract Objectives Our aim was to describe the pharmacokinetics of cefazolin in paediatric patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) who received cefazolin for peri-operative surgical prophylaxis in addition..
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Abstract Summary We investigated microcirculatory perfusion disturbances following cardiopulmonary bypass in the early postoperative period and whether the course of these disturbances mirrored restoration of endothelial glycocalyx integrity. We performed..
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Abstract Pediatric cardiac surgical patients are at particular risk for post-cardiopulmonary bypass hemorrhage. Moreover, both the incidence and volume of have been associated with increased morbidity in pediatric cardiac patients. Transfusion..
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Abstract Extracorporeal membrane oxygenation is a rapidly emerging treatment for respiratory or cardiac failure and is used as a bridge to recovery, transplant, or destination therapy. Adult patients receiving extracorporeal..
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Abstract Background The predictors and independent outcome association of after cardiac surgery are important and yet poorly characterised. Methods We performed a retrospective of cardiac surgery patients between January 2009 and March..
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Abstract Background: Administering isoflurane 2.5% into the oxygenator during cardiopulmonary bypass results in no patient movement. However, doing so may result in an excessive depth of anaesthesia particularly, when hypothermia..
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Abstract Legionella community–acquired pneumonia necessitating veno-venous extracorporeal membrane oxygenation for severe acute respiratory distress syndrome has been reported in adults. However, few options remain in cases of refractory hypoxemia on..
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Abstract Background Venoarterial (VA) (ECMO) application in postcardiotomy shock (PCS) and non-PCS is increasing. VA-ECMO plays a critical role in the management of these patients, yet may be associated with serious..
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Abstract Objective induces degradation of . The authors hypothesized that inflammation is an important determinant of glycocalyx degradation in patients undergoing cardiac surgery with (CPB). Design A prospective . Setting Operation theater and..
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Case 1 A 78-year-old male diabetic patient underwent elective coronary artery bypass grafting (CABG). His insulin therapy had been changed recently to human insulin (Humulin M3; Eli Lilly Italia, Sesto..
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Abstract Objectives To determine whether precardiopulmonary bypass (CPB) normalization of levels in infants to 100% improves heparin sensitivity and during CPB and has beneficial effects into the . Design Randomized, double-blinded, placebo-controlled prospective..
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Abstract Background Arginine vasopressin (AVP) is a naturally occurring peptide with diverse effects mediated through selective V1 and V2 receptors. About 10% of patients undergoing cardiopulmonary bypass develop postoperative vasodilatory..
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Abstract The objective of this study is to establish reliable markers for mortality in children with refractory cardiogenic shock who underwent extracorporeal membrane oxygenation. A retrospective observational cohort study was..
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Abstract Background Despite concern that cardiac surgery may adversely affect cognition, little evidence is available from population-based studies using presurgery data. With the use of the Health and Retirement Study,..
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OBJECTIVES Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence..
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Summary Thromboelastometry point‐of‐care coagulation testing facilitates optimised management of bleeding. Previous thromboelastometry systems required the blood sample and liquid reagents to be pipetted in several manual steps by trained personnel...
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