Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis..
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Abstract Pump thrombosis and stroke are serious complications of left ventricular assist device (LVAD) support. The aim of this study was to test the ability of an accelerometer to detect..
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Abstract Systemic anticoagulation is a standard of care in adult patients supported by extracorporeal membrane oxygenation (ECMO) to prevent circuit thrombosis and subsequent thromboembolic events. Unfractionated heparin has long been..
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POSTOPERATIVE PULMONARY dysfunction, a known complication after cardiac surgery, is associated with significant morbidity and mortality. Pulmonary complications include hypoxemia; increased work of breathing; atelectasis; pneumonia; and in 2% to..
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Abstract Aim To assess the use of (ECPR), compared with manual or mechanical cardiopulmonary resuscitation (CPR), for (OHCA) and in-hospital cardiac arrest (IHCA) in adults and children. Methods The PRISMA guidelines were..
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Abstract We currently perform open-heart procedures using bloodless priming of cardiopulmonary bypass circuits regardless of a patient’s body weight. This study presents results of this blood-saving approach in neonates and..
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Abstract Despite the advantages of extracorporeal membrane oxygenation (ECMO), secondary catheter infection remains a major concern during ECMO support. In this study, to clarify the mechanism of ECMO catheter-related infection, we evaluated the..
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Abstract is associated with impairment of cardiovascular, pulmonary, gastrointestinal, and renal physiology with significant perioperative consequences and has been linked with higher morbidity and mortality after cardiac surgery. Cardiac surgery..
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Abstract Background: Left ventricular (LV) afterload increase with protracted aortic valve (AV) closure may represent a complication of veno-arterial extracorporeal membrane oxygenation (V-A ECMO). The aim of the present study..
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Abstract Background Bleeding contributes to the high mortality of venovenous membrane oxygenation (vvECMO). The development of acquired von Willebrand syndrome (AVWS) has been identified as relevant pathology during ECMO. This study..
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Abstract Chipmunk as a food-storing hibernator naturally undergoes hibernation that is linked to great changes in systemic physiology and could protect the central nervous system during drastically reduced cerebral blood..
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Abstract Background Crystalloid priming is a cost-effective, free from immunological reactions, and independent from human plasma delivery. However, there is some debate on the negative impact of low plasma colloid..
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Objective To determine the relationships between hypothermia and pH at surgery end and postoperative red blood cell (RBC) transfusion in massively transfused adult cardiac surgery patients. Design . Setting Single..
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HYPOTHERMIC CIRCULATORY arrest combined with selective cerebral perfusion commonly is employed to permit surgical repair of the ascending and transverse aorta. A variety of perfusion techniques are employed, including retrograde..
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CURRENTLY, MINIMALLY INVASIVE cardiac surgery (MICS) is very popular. In most cases, cardiopulmonary bypass (CPB) is used with femoral arterial cannulation, and the whole body is perfused in a retrograde..
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Objective Adequate , measured using (ACT), is important during vascular and cardiac surgeries. Unfractionated heparin is the most common used. The purpose of this analysis was to compare the i-STAT ACT (iACT) to..
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THE INCIDENCE OF oxygenator thrombosis during cardiopulmonary bypass (CPB) has decreased significantly with the advent of modern heparin-coated bypass circuits, but rare failures continue to be reported at a rate..
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Abstract Introduction: Pulsatile extracorporeal circulation may improve organ perfusion during cardiac surgery. Some minimally invasive extracorporeal circulation (MiECC) systems allow pulsatile perfusion. The present study investigated the influence of arterial..
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Abstract In a randomized clinical trial in China of 244 adults undergoing elective, multiple valve replacement surgery, Lei and colleagues administered 80 parts per million nitric oxide (NO) gas during..
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Abstract The use of extracorporeal circulation for cardiac surgery and extracorporeal life support poses tremendous challenges to the hemostatic equilibrium given its diametric tendency to trigger hyper‐ and hypocoagulopathy. The..
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Abstract Background For diabetic patients who require (CABG) operation, controversy persists whether an off-pump or an on-pump approach may be advantageous. This US-based, multicenter, randomized, controlled trial, Department of Veterans Affairs..
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Abstract (IE) after (TAVI) and surgical (SAVR) is a rare but life-threatening complication. Paravalvular regurgitation, compression of native leaflets, and space between transcatheter and native valves could dispose recipients at increased risk of IE..
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Abstract Veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) is increasingly commonly used to treat acute cardiac or pulmonary failure because of a wide range of etiologies. However, despite progressively improving outcomes,..
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Abstract Extracorporeal circulation causes many deleterious effects on blood cells. Low-level light therapy (LLLT) in the red/near-infrared spectral range is known for its cytoprotective properties but its use during cardiopulmonary..
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Abstract BACKGROUND: Tranexamic acid (TXA) is a common antifibrinolytic agent used to minimize bleeding in cardiac surgery. Up to 50% cardiac surgical patients have chronic renal dysfunction (CRD). Optimal dosing..
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Abstract Acute aortic syndromes are a distinct group of pathologies involving the wall of the aorta that present acutely and can be potentially fatal unless treated in a timely fashion...
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Abstract There is a delicate balance between bleeding and clotting in patients on circuits such as ventricular assist devices or extracorporeal membrane oxygenation. Traditional coagulation tests, prothrombin time, activated partial..
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Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been used for refractory cardiogenic shock; however, it is associated with increased left ventricular afterload. Outcomes associated with the combination of a percutaneous..
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Abstract Objectives The aim of this pilot study was to elucidate the effects of exogenous (NO) supply to the circuit for cardioprotection against during (CABG) with (CPB). Methods A total of 60 patients with scheduled for..
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Abstract Background: Ultrafiltration during cardiopulmonary bypass (CPB) reduces fluid overload and inflammatory mediators in open-heart surgery and is thought to reduce the risk of red blood cell (RBC) transfusion. We..
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