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Transesophageal echocardiography uncovers iatrogenic liver injury during minimally invasive mitral valve surgery: case report

Abstract Background Minimally invasive cardiac surgery (MICS) reduces surgical trauma but limits direct visualization of surrounding structures, posing a risk of unrecognized injury. Case presentation A 65-year-old man with alcoholic..

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Post-resuscitation care after adult extracorporeal cardiopulmonary resuscitation: A scoping review

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used in adults with refractory cardiac arrest. However, post-resuscitation care in this population remains heterogeneous, evidence-based recommendations are lacking, and most evidence..

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Heparin Resistance in Cardiac Surgery with Cardiopulmonary Bypass: Mechanisms, Clinical Implications, and Evidence-Based Management

Abstract Background: Unfractionated heparin (UFH) is the standard anticoagulant during cardiopulmonary bypass (CPB). A clinically relevant subset develops heparin resistance (HR)—failure to reach adequate anticoagulation with usual UFH—raising thrombotic risk..

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Predictors of VV-ECMO weaning safety: longitudinal ventilatory ratio assessment during sweep gas off trials, a retrospective cohort study

Abstract Background Separation from venovenous extracorporeal membrane oxygenation (VV-ECMO) is a pivotal transition for patients with acute respiratory distress syndrome (ARDS). Impaired alveolar ventilation more so than oxygenation may be..

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Trauma Extracorporeal Membrane Oxygenation in Argentina: Complications, Mortality, and Long-term Outcomes

Abstract Extracorporeal membrane oxygenation (ECMO) for trauma is underreported in Latin America. We conducted a cohort study in four centers from Argentina (2015–2024), including all adults with polytrauma (defined as..

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Understanding the influence of temporary neurologic dysfunction in the outcomes of aortic surgery

Abstract Objective Temporary neurologic dysfunction (ND) is common after aortic surgery. The Valve Academic Research Consortium 3 classifies ND as NeuroARC Type 1 (stroke), Type 2 (covert injury), and Type..

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Effect of Ozone Autohemotherapy on Inflammatory Response and Postoperative Cognitive Function in Patients Undergoing Valve Replacement with Cardiopulmonary Bypass

Abstract Objective: We herein probed the effects of ozone autohemotherapy (O3-AHT) on inflammatory response and postoperative cognitive function in patients undergoing valve replacement with cardiopulmonary bypass (CPB). Methods: Totally, 130..

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Extracorporeal membrane oxygenation in a low-volume whole nation cardiothoracic centre: short- and long-term mortality, survivors` quality of life and symptoms…

Abstract Background For over three decades ECMO-treatment has been provided in our low-volume nationwide cardiothoracic centre in Iceland. This research aims to examine both the short- and long-term results of..

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Evolution of extracorporeal membrane oxygenation: historical milestones and advanced developments

Abstract Extracorporeal membrane oxygenation (ECMO) has a history that is a testament to the pioneering spirit of medical innovators. It is intricately linked with the development of cardiopulmonary bypass (CPB)..

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Percutaneous Postclosure vs Femoral Arterial Cutdown for Venoarterial Extracorporeal Membrane Cannulation Sites

Abstract Background This study sought to examine the outcomes of percutaneous postclosure of large-bore femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) cannulas compared with a traditional open cutdown technique. Methods Between..

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Efficacy and Feasibility of Preoperative Autologous Blood Donation in Elective On-pump Cardiac Surgeries: A Propensity-score Matching Study

Abstract Objective: The global shortage of blood resources has become a significant concern. This study aimed to assess the effects and feasibility of preoperative autologous blood donation (PABD) in elective..

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Multiple faces of equity in extracorporeal membrane oxygenation

Abstract Health care is not a luxury in the sense of being an enjoyment or an unnecessary indulgence, but inequality and inaccessibility can make certain services seem like luxuries. Health..

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Comparison of myocardial cooling effects between antegrade and retrograde cardioplegia: a retrospective study using thermography

Abstract Background Cardioplegia is delivered via antegrade, retrograde, or combined perfusion routes. Antegrade cardioplegia follows the physiological path but may be less effective in patients with severe coronary disease. Retrograde..

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Redefining the role of perfusionists in ECMO: from technical operators to clinical stakeholders

Abstract Extracorporeal Membrane Oxygenation (ECMO) is increasingly used in refractory cardiac and respiratory failure, yet the role of perfusionists remains narrowly defined. While traditionally viewed as technical operators, perfusionists possess..

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What is the ideal solution for washing salvaged red blood cells using a cell saver for autotransfusion during surgery

Abstract There are three reasons why perfusionists and autotransfusionists around the globe still use Normal Saline with cell savers; (1) This what they were taught by their peers and/or didactic..

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Peripheral veno-arterial ECMO cannulation in children: Review of the relevant ELSO publications

Abstract Background Peripheral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) cannulation in children poses a significant clinical challenge due to wide variations in body size, vessel caliber, and risk profiles. Purpose..

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Use of Andexanet Alfa to Reverse Heparin After Cardiopulmonary Bypass

Abstract Heparin is the primary anticoagulant used for cardiopulmonary bypass and requires reversal to prevent postoperative bleeding. Protamine sulfate is the only United States Food and Drug Administration–approved heparin reversal..

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ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part III: Postoperative Considerations

Abstract The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no..

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Getinge’s ECMO simulation Global Webinar

Getinge's ECMO Simulation Global Webinar During this webinar, live participants will have the opportunity to test and enhance their ECMO knowledge by engaging in an interactive eCPR scenario using Pratico Santé’s..

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Leveraging the perfusionist-surgeon dyad to improve the culture of safety

Abstract The cardiac surgical operating room is a complex, high risk environment dependent on efficient teamwork and communication between multiple role groups to deliver safe and effective care. As awareness..

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Mitral Valve Surgery for Rheumatic Heart Disease in Indigenous Australians: A 27-Year Cohort Study of Repair Versus Replacement Outcomes

Abstract Aim This study aimed to evaluate long-term outcomes of mitral valve surgery for rheumatic heart disease (RHD) in Indigenous Australians, comparing survival and revision rates between valve repair and..

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Survival on the clock: rethinking where and how we deliver ECPR

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) is the only therapy capable of rescuing patients from refractory cardiac arrest, but its effectiveness is critically dependent on time to reperfusion. The system proposed..

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Zero-Balance Ultrafiltration Reduces Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Randomized Controlled Trial

Abstract Purpose To assess the effects of conventional ultrafiltration and conventional plus zero-balanced ultrafiltration on delirium and cognition in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods A total..

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Extracorporeal Cardiopulmonary Resuscitation and Organ Donation: A Modified Delphi Study Exploring Cumulative Impact Index Feasibility

Abstract Although the goal of extracorporeal cardiopulmonary resuscitation (ECPR) remains survival with meaningful neurologic recovery, secondary contribution to organ donation is increasingly recognized. We identified standardized outcome metrics for quality..

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Impact of rhythm changes during CPR on ECPR outcomes: an ELSO Registry study

Abstract Background Cardiac rhythm is a well-established prognostic factor in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR); however, existing evidence is primarily limited to small, single-center studies. This study aimed to..

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Outcomes of Venopulmonary Extracorporeal Membrane Oxygenation Conversion in Patients With Severe Respiratory Failure on Venovenous Support

Abstract Severe respiratory failure is frequently complicated by right ventricular dysfunction (RVD), which occurs in 20–50% of cases. In patients on venovenous extracorporeal membrane oxygenation (VV ECMO) with refractory RVD,..

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Heparin Resistance in Cardiac Surgery with Cardiopulmonary Bypass: Mechanisms, Clinical Implications, and Evidence-Based Management

Abstract Background: Unfractionated heparin (UFH) is the standard anticoagulant during cardiopulmonary bypass (CPB). A clinically relevant subset develops heparin resistance (HR)—failure to reach adequate anticoagulation with usual UFH—raising thrombotic risk..

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Antimicrobial pharmacokinetics and stewardship in critically Ill adult patients receiving ECMO: Challenges, evidence, and future directions

Abstract Infection is a common indication and complication for extracorporeal membrane oxygenation (ECMO), and adult ECMO recipients face increased nosocomial infection risk. Effective antimicrobial dosing in these patients remains difficult..

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Effects of hyperoxia in pediatric perfusion patients: a scoping review

Abstract Hyperoxia in pediatric cardiopulmonary bypass patients is associated with adverse effects, including reoxygenation injury, increased mortality, heightened inflammatory response, and cerebral injury. Although prior research has demonstrated a correlation..

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ECMO to CPB: A single circuit approach

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) are used during pediatric heart surgery to provide cardiopulmonary support to patients as they undergo and recover from surgical..

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