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Neurological monitoring in ECMO patients: current state of practice, challenges and lessons

Abstract Background Extracorporeal membrane oxygenation (ECMO) in critically ill patients serves as a management option for end-stage cardiorespiratory failure in medical and surgical conditions. Patients on ECMO are at a..

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Impact of Drainage Cannula Size and Blood Flow Rate on the Outcome of Patients Receiving Venovenous ECMO for ARDS: An…

Impact of Drainage Cannula Size and Blood Flow Rate on the Outcome of Patients Receiving Venovenous ECMO for ARDS: An ELSO Registry Analysis

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Does Tracheostomy Improve Outcomes in Those Receiving Venovenous Extracorporeal Membrane Oxygenation?

Abstract Patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO) often require extended periods of ventilation. We examined the role of tracheostomy on outcomes of patients supported with VV-ECMO. We reviewed all patients at our institution..

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Association between enteral feeding and gastrointestinal complications in children receiving extracorporeal life support: A retrospective cohort study

Abstract Background Extracorporeal life support is an accepted treatment modality for children with severe cardiac and/or respiratory dysfunction. However, after a period of inadequate gut perfusion, clinicians are often reluctant..

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Analysis of perioperative corticosteroid therapy in children undergoing cardiac surgery: A systematic review and meta-analysis

Abstract The advantages and disadvantages of using corticosteroids in children undergoing cardiac surgery is still contentious. To examine how perioperative corticosteroids affect postoperative mortality and clinical outcomes in pediatric cardiac..

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Cardiac arrest and cardiopulmonary resuscitation in pediatric patients with cardiac disease: a narrative review

Abstract Children with cardiac disease are at a higher risk of cardiac arrest as compared to healthy children. Delivering adequate cardiopulmonary resuscitation (CPR) can be challenging due to anatomic characteristics,..

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Coronary angiography findings in resuscitated and refractory out-of-hospital cardiac arrest: A systematic review and meta-analysis

Abstract Introduction Coronary angiography (CAG) frequently reveals coronary artery disease (CAD) after out-of-hospital cardiac arrest (OHCA), but its use is not standardized and often reported in different subpopulations. This systematic..

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“Bridging the Gap” international ECLS training and simulation - evaluation of the 10th educational corner on EuroELSO congress 2022 in…

Abstract Introduction:   Simulation training offers an authentic team-based learning opportunity without risk to real patients. The Educational Corner at the annual congress of the European Branch of Extracorporeal Life..

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Decannulation of Percutaneous Femoro-femoral VA-ECMO Using the Manta Vascular Closure Device

Abstract Percutaneous cannulation improved femoro-femoral veno-arterial Extracorporeal Membrane Oxygenation (VA-ECMO) results, reducing infectious complications, but remains limited by vascular complications related to the arterial decannulation. Several techniques were described to perform a percutaneous decannulation..

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Integrated Analysis of Tracheobronchial Fluid from Before and After Cardiopulmonary Bypass Reveals Activation of the Integrated Stress Response and Altered…

Abstract Objective: We aim to comprehensively describe the transcriptional activity and signaling of pulmonary parenchymal and immune cells before and after cardiopulmonary bypass (CPB) by using a multi-omic approach coupled..

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Clinical decision support for ExtraCorporeal Membrane Oxygenation: Will we fly by wire?

Abstract Prognostic modelling techniques have rapidly evolved over the past decade and may greatly benefit patients supported with ExtraCorporeal Membrane Oxygenation (ECMO). Epidemiological and computational physiological approaches aim to provide..

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The ProtekDuo® Cannula for Acute Mechanical Circulatory Support

Abstract The ProtekDuo® is a dual lumen cannula that can be used in numerous configurations to treat cardiogenic shock and hypotension. Its default function is as a temporary percutaneous right..

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Minimized Hemodiafiltration for Extracorporeal Membrane Oxygenation in Infants

Abstract Background  Fluid overload is a serious complication in the treatment of infants with extracorporeal membrane oxygenation (ECMO). Volume overload leads to prolonged ECMO therapy if left untreated. The renal..

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ECMOLIFE intra-hospital transport in life-saving for pulmonary vein obstruction

Abstract Background Transport with extracorporeal membrane oxygenation (ECMO) in the hospital setting can become a challenge as well as in the out-of-hospital setting. In particular, the management of intra-hospital transport..

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Hypoxic-Ischemic Brain Injury in ECMO: Pathophysiology, Neuromonitoring, and Therapeutic Opportunities

Abstract Extracorporeal membrane oxygenation (ECMO), in conjunction with its life-saving benefits, carries a significant risk of acute brain injury (ABI). Hypoxic-ischemic brain injury (HIBI) is one of the most common..

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Extracorporeal hemoadsorption in critically ill COVID-19 patients on VV ECMO: the CytoSorb therapy in COVID-19 (CTC) registry

Abstract Objectives: The CytoSorb therapy in COVID-19 (CTC) registry evaluated the clinical performance and treatment parameters of extracorporeal hemoadsorption integrated with veno-venous extracorporeal membrane oxygenation (VV ECMO) in critically ill COVID-19..

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Outcomes With Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Suspected Acute Myocarditis: 10-Year Experience From the Extracorporeal Life Support Organization Registry

Abstract Background: Acute myocarditis can result in severe hemodynamic compromise requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO). Outcomes and factors associated with mortality among myocarditis patients are not well described in..

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Why is it beneficial to use CytoSorb® during Heart Transplantation? – Results of a recent RCT

Description Brand new data and publications - introduced and discussed by the author: Assoc. Prof. Endre Németh, Semmelweis University Budapest Moderation: Dr. Marijana Matejic-Spasic, CytoSorbents Europe GmbH  

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Improving Patient Blood Management Programs: An Implementation Science Approach

Abstract Organized patient blood management (PBM) programs function in numerous hospitals and health systems around the world contributing to improved patient outcomes as well as increased patient engagement, decreased resource..

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A norepinephrine weaning strategy using dynamic arterial elastance is associated with reduction of acute kidney injury in patients with vasoplegia…

Abstract Study objective To evaluate the impact of a dynamic arterial elastance guided  weaning strategy on the occurrence of  (AKI) in  with  after cardiac surgery. Design A post-hoc analysis of a monocentric . Setting A..

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Sodium citrate effectively used in shed mediastinal blood autotransfusion after cardiac surgery

Abstract Background We used sodium citrate as an alternative anticoagulation agent to heparin in the procedure of autologous blood transfusion with patients with postoperative haemorrhage after CPB. The aim of..

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Longitudinal assessment of cerebral blood volume variation in human neonates using ultrafast power Doppler and diverging waves

Abstract Longitudinal assessment of brain perfusion is a critical parameter for neurodevelopmental outcome of neonates undergoing cardiopulmonary bypass procedure. In this study, we aim to measure the variations of cerebral..

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Considerations for integrating wearables into the everyday healthcare practice

Abstract Wearable technologies are becoming ever more popular as suggested tools for use in modern medicine. Studies evidence their growing pragmatism and provision of objective data for a more informative..

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The role and timing of cardiopulmonary bypass in the surgical repair of traumatic cardiac injury

Abstract Objectives The management of traumatic cardiac injury (TCI) may require a prompt treatment, including the use of cardiopulmonary bypass (CPB) followed by surgical repair. This study evaluated the surgical..

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Comparison of Prothrombin Complex Concentrate with Activated Factor VII Use for Bleeding Following Cardiopulmonary Bypass in Children

Abstract Objective This study aims to compare the efficacy and safety of activated recombinant factor VII (rFVIIa) and prothrombin complex concentrate (PCC) in the treatment of bleeding complications following surgery..

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Vasoplegic syndrome in cardiovascular surgery; evaluating effects of Sevoflurane and Glibenclamide in a porcine model

Abstract Background Vasoplegic syndrome is frequently observed during cardiac surgery and resembles a complication of high mortality and morbidity. There is a clinical need for therapy and prevention of vasoplegic syndrome..

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Patient, Clinician, and Institution level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis

Abstract Background Conflicting evidence exists regarding the risks and benefits of inotropic therapies during cardiac surgery, and the extent of variation in clinical practice remains understudied. Therefore, the authors sought..

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Evaluation of Latex Immunoturbidimetric Assay Thresholds and HIT in Cardiothoracic Surgery

Abstract Background Heparin-induced thrombocytopenia (HIT) is a common differential diagnosis in cardiothoracic surgery. The latex immunoturbidimetric assay (LIA) is an enhanced immunoassay that has recently been introduced for the detection..

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3 myths about ECMO that are costing hospitals and patients

Abstract Although the global pandemic is officially over, it has left a permanent mark on the health care landscape, reshaping the dynamics of hospitals in the United States. While staffing..

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Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes

Abstract Oxygen is toxic across all three domains of life. Yet, the underlying molecular mechanisms remain largely unknown. Here, we systematically investigate the major cellular pathways affected by excess molecular..

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