Home

thumbnail
0 comment

Multimodal characterization of flow-induced thrombus initiation and growth in extracorporeal membrane oxygenation

Abstract In cases of severe cardiopulmonary failure, extracorporeal membrane oxygenation (ECMO) may be temporarily used as a life-saving support for cardiac and/or lung function. Operating under non-physiological flow conditions, characterized..

Read More
thumbnail
0 comment

From fast track to enhanced recovery after Cardiac surgery: 15 years of experience with the Leipzig concept in a specialized…

Abstract Background Enhanced Recovery After Cardiac Surgery (ERACS) has become the standard of care for selected patients. This study evaluated the evolution of the Leipzig concept in a specialized postanaesthesia..

Read More
thumbnail
0 comment

How does rewarming temperature affect bleeding after mitral valve repair?

Abstract Objective So far, evidence is scarce regarding the impact of rewarming temperature on bleeding after cardiac surgery under cardiopulmonary bypass (CPB). We seek to evaluate how rewarming temperature affects..

Read More
thumbnail
0 comment

Building an Extracorporeal Membrane Oxygenation Digital Twin Using High-Resolution Patient Data: An artificial intelligence model for virtual reality simulation

Abstract OBJECTIVES Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy for severe cardiopulmonary failure, but structured training remains constrained by costs, logistics, and the absence of validated high-fidelity simulators. This..

Read More
thumbnail
0 comment

High-Exchange Ultrafiltration to Enhance Recovery After Pediatric Cardiac Surgery: The ULTRA Randomized Controlled Trial

Abstract Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) is associated with systemic inflammation. This trial aimed to determine whether continuous high-exchange ultrafiltration during CPB has a clinical immunomodulatory effect...

Read More
thumbnail
0 comment

Current rat models of extracorporeal life support following global ischaemia: a scoping review

Abstract Introduction Small animal models are indispensable in cardiovascular research. This scoping review aims to provide an overview of contemporary rat models for extracorporeal life support (ECLS) after global ischaemia...

Read More
thumbnail
0 comment

Association Between Systemic Anticoagulation and Outcomes in Patients With Acute Respiratory Distress Syndrome Receiving Venovenous Extracorporeal Membrane Oxygenation: Insights From…

Abstract Objective:  To evaluate whether systemic anticoagulation therapy affects the survival of adult patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO) for acute respiratory distress syndrome (ARDS). Design:  Multicenter retrospective study...

Read More
thumbnail
0 comment

Adjuvant Autologous Platelet-Rich Plasma Gel for Decreasing Blood Loss in Posterior Placenta Previa: A Case Series and Literature Review

Abstract We reported two cases of posterior placenta previa managed with elective cesarean delivery and adjunctive autologous platelet-rich plasma (PRP) gel. Twelve milliliters of PRP gel were used to cover..

Read More
thumbnail
0 comment

Recommendations in Extracorporeal Cardiopulmonary Resuscitation Post Resuscitation Care Via An International, Modified Delphi Approach

Abstract Background The global adoption of extracorporeal cardiopulmonary resuscitation (ECPR) for cardiac arrest is accelerating, reflecting its potential to improve outcomes in select patient populations. Although research has increasingly focused..

Read More
thumbnail
0 comment

Systemic inflammatory response syndrome after cardiopulmonary bypass: prevalence, predictors, and outcomes

Abstract Background Systemic Inflammatory Response Syndrome (SIRS) is a frequent and critical complication following cardiac surgery, particularly in patients undergoing cardiopulmonary bypass (CPB). Although SIRS is associated with increased morbidity..

Read More
thumbnail
0 comment

Comparison of Classical Blood Cardioplegia and Modified Del Nido Cardioplegia on Postoperative Serum Lactate Levels and Extubation Times

Abstract Objective: To compare the effects of intermittent classical blood cardioplegia and single-dose modified Del Nido cardioplegia on postoperative serum lactate levels and extubation time in patients undergoing coronary artery bypass..

Read More
thumbnail
0 comment

Pediatric Extracorporeal Membrane Oxygenation (ECMO) Transport Safety—Regional and National Experiences and Literature Review

Abstract Background/Objectives: Venovenous extracorporeal membrane oxygenation (VV ECMO) supports reversible respiratory failure when mechanical ventilation fails. Technological advances and specialized teams now enable ECMO initiation at referring centers, even for high-risk..

Read More
thumbnail
0 comment

Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary…

Abstract Objectives To assess whether intravenous lidocaine reduces the systemic inflammatory response associated with cardiopulmonary bypass (CPB) and improves clinical outcomes in adult patients undergoing elective valvular and/or coronary cardiac..

Read More
thumbnail
0 comment

Prevention of blood dilution during cardiopulmonary bypass surgery in a cat with ventricular septal defect

Abstract A six-month-old, 3.3-kg, intact male American shorthair cat with a ventricular septal defect (VSD) underwent open-heart surgery using total cardiopulmonary bypass. Repair of the VSD was performed via a..

Read More
thumbnail
0 comment

Predictors of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) failure: analysis of comorbidities and complications – a 10-year experience

Abstract Introduction Regardless of its effectiveness, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support is not a risk-free method. Its use is associated with high complication and mortality rates, especially in patients..

Read More
thumbnail
0 comment

Impact of Endogenous Melatonin Status on Perioperative Oxidative Stress in Pediatric Cardiac Surgery With Cardiopulmonary Bypass

Abstract Objectives This study aimed to investigate whether prebypass endogenous melatonin concentrations are associated with perioperative oxidative DNA injury, indexed by urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG), and to explore their relationship with..

Read More
thumbnail
0 comment

Outcomes in Adult Patients Requiring Multiple Runs of Extracorporeal Membrane Oxygenation

Abstract Objectives This study describes a single-institution experience of adult patients supported with multiple runs of extracorporeal membrane oxygenation (ECMO) during the same hospitalization. We aim to assess complication and..

Read More
thumbnail
0 comment

A Homemade Low-Cost Agar-Agar Extracorporeal Membrane Oxygenation Cannulation Model for Extracorporeal Resuscitation Simulation

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) using venoarterial extracorporeal membrane oxygenation (VA ECMO) is a life-saving intervention for selected patients in refractory cardiac arrest. Given the procedure’s technical complexity and time-critical..

Read More
thumbnail
0 comment

Circulatory arrest time above 30 min have significantly detrimental effects on the outcomes of type a aortic dissection repair

Abstract Background Acute aortic dissection of the ascending aorta is a life-threatening disease that poses a significant challenge for cardiovascular surgeons. Dissection of the aorta typically occurs when the aortic..

Read More
thumbnail
0 comment

Comparison of Left Ventricular Unloading Strategies During Extracorporeal Membrane Oxygenation

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) offers cardiopulmonary support with the tradeoff of increased left ventricular (LV) afterload and its adverse sequelae. LV decompression strategies include the use of intra-aortic..

Read More
thumbnail
0 comment

Application of VA-ECMO combined with IABP in a patient with cardiac arrest following fulminant myocarditis

Abstract Background Fulminant myocarditis is a severe cardiac condition characterized by rapid progression and high mortality. In recent years, advancements in medical technology, particularly the application of mechanical circulatory support,..

Read More
thumbnail
0 comment

Left and right myocardial ventricular energetics during cardioplegic ischemic arrest and reperfusion in patients undergoing cardiac surgery

Abstract Background Effective myocardial protection during cardiac surgery is essential, yet the differential metabolic stress of the left (LV) and right ventricles (RV) to ischemia–reperfusion remains poorly characterized. Methods This..

Read More
thumbnail
0 comment

Advances in Heparin Reversal Agents: Design Strategies, Structural Features, and Pharmacological Insights

Abstract Heparin is among the most widely used anticoagulants worldwide, with an annual market of ∼$4 billion. It also poses potential bleeding risks (0.5–5%), occasionally life-threatening, necessitating heparin reversal agents...

Read More
thumbnail
0 comment

Triple-dose bolus versus continuous infusion of tranexamic acid: impacts on clinical outcomes in isolated coronary artery bypass surgery

Abstract Background In cardiac surgery, intraoperative tranexamic acid (TXA) is commonly used and highly recommended approach for managing perioperative bleeding. Nevertheless, a standardized dose and administration protocol remains undefined. This..

Read More
thumbnail
0 comment

The role of mediastinal blood in the development of postoperative atrial fibrillation after cardiac surgery

Abstract Introduction Atrial fibrillation (AF) is the most common arrhythmia following cardiac surgery. Although many risk factors have been studied, none has emerged as a dominant and widely applicable prophylactic measure. Aim..

Read More
thumbnail
0 comment

Development of an Optical Sensor for Real-Time Monitoring of Hemodynamic Parameters in Extracorporeal Settings

Abstract Objective: Whole blood oxygen saturation and hemoglobin concentration are key markers of health across a variety of clinical contexts. Extracorporeal systems (dialysis, cardiopulmonary bypass, ECMO, etc.) require close monitoring..

Read More
thumbnail
0 comment

Central veno-arterial ECMO via an aortic prosthetic graft as significant alternative to peripheral ECMO cannulation: evaluation of patient outcomes in…

Abstract Background For patients presenting with cardiogenic shock due to acute myocardial ischaemia, veno-arterial extracorporeal membrane oxygenation (ECMO) is often the only potential lifesaving intervention remaining when revascularisation does not..

Read More
thumbnail
0 comment

Evaluating Topical Antifibrinolytics in Cardiac Surgery: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis

Abstract Introduction Lysine analog antifibrinolytics (LAAF) like tranexamic acid (TXA) and aminocaproic acid (EACA) reduce intraoperative blood loss, especially in cardiac surgery where bleeding risks are high. These LAAFs inhibit..

Read More
thumbnail
thumbnail
0 comment

DCD step by Step for Heart and lung donation

      1. Donor Identification •Identify a potential DCD donor (Maastricht category III or II in some systems). •Patient has devastating neurologic or systemic injury but does not meet..

Read More