Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory paediatric in-hospital cardiac arrest (IHCA). Although rapid initiation of extracorporeal life support (ECLS) is widely considered critical, the relative..
Read MoreAbstract Intraoperative adverse events (IAEs) are a significant unresolved problem in surgery. Breakdown in nontechnical skills (NTS) of surgical team members are a significant contributor to preventable IAEs [], Surgical..
Read MoreAbstract Artificial intelligence (AI) has rapidly emerged as a transformative force across multiple scientific and clinical domains, demonstrating remarkable capabilities in data analysis, pattern recognition, and predictive modeling. In the..
Read MoreAbstract Background Extracorporeal circulation (ECC) is increasingly supported by biomaterials engineered to minimize chemical leaching, and many biomedical manufacturers have now removed or substantially reduced phthalate plasticizers particularly di(2-ethylhexyl) phthalate..
Read MoreAbstract Background Acute kidney injury is a common complication of cardiac surgery and may lead to kidney failure. In a large sample sourced from national registries, we estimated the risk..
Read MoreAbstract Introduction Bleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes..
Read MoreAbstract Factor XIII (FXIII) contributes to clot stability and reduces clot susceptibility to lysis through fibrin cross-linking. Standard coagulation tests like prothrombin time and activated partial thromboplastin time do not..
Read MoreAbstract Background and Objectives: Overt perioperative stroke remains a feared complication of adult cardiac surgery. Diffusion-weighted magnetic resonance imaging (DWI-MRI) has revealed a more prevalent form of cerebral injury, termed..
Read MoreAbstract Decompensated differential carbon dioxide (CO2) removal can occur during spontaneous breathing on peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) when a low right radial arterial partial pressure of carbon..
Read MoreAbstract Objective Myocardial protection research in adult cardiac surgery has increasingly examined single dose del Nido cardioplegia alongside conventional multidose blood cardioplegia. Using a scientometric modeling approach, this study aims..
Read MoreAbstract Aim Acute kidney injury (AKI) is a major complication of coronary artery bypass grafting (CABG). Existing predictive models show limited accuracy and rarely include modifiable intraoperative risk factors. Therefore,..
Read MoreAbstract Background/Objectives: Volatile anesthetic dosing during cardiopulmonary bypass (CPB) is poorly standardized. We estimated the end-tidal sevoflurane (ETsevo) concentration required to maintain adequate anesthesia during CPB and investigated the effects..
Read MoreAbstract Background Acute myocardial infarction-related cardiogenic shock (AMI-CS) remains associated with extremely high mortality in patients with acute myocardial infarction despite timely revascularization and advances in mechanical circulatory support (MCS)...
Read MoreAbstract Introduction Early detection of acute brain injury (ABI) in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO) is challenging. We aimed to investigate if heart rate variability (HRV) in..
Read MoreAbstract Background/Objectives: Acute kidney injury (AKI) remains a significant complication following cardiac surgery, associated with increased morbidity and mortality. The early detection of AKI is limited by the cost, availability,..
Read MoreAbstract Despite the advances in technology, new patient populations, new medications, and multiple monitoring algorithms for anticoagulation, bleeding, and thrombosis complications remain high among those receiving extracorporeal life support (ECLS)..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has increasingly been used in patients with refractory severe cardiorespiratory failure in recent years. The use of ECMO necessitates anticoagulation as blood passes through an..
Read MoreAbstract Background Accidental hypothermia is the unintentional decrease in core body temperature below 35°C due to environmental exposure. Severe hypothermia, defined as a core body temperature less than 28°C, can..
Read MoreAbstract Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannulation (PC)..
Read MoreAbstract Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respiratory failure refractory to conventional measures. Its application has broadened across a wide spectrum..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric cardiac arrest relies on enhanced resources and time-critical decision-making. We aimed to evaluate variations in systems and clinical practice among extracorporeal membrane oxygenation..
Read MoreAbstract Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) carries substantial transfusion requirements, exposing patients to increased risks of complications during hospital stay. This study evaluates the clinical impact of..
Read MoreAbstract The recent article by Ko et al., entitled “The effects of extracorporeal blood purification (oXiris®) in patients with cardiogenic shock who require VA-ECMO (CLEAN ECMO): a prospective, open-label, randomized..
Read MoreAbstract Objectives Targeted temperature management (TTM) is the standard of care for comatose cardiac arrest survivors. However, evidence regarding its long-term neurological impact specifically on in-hospital cardiac arrest (IHCA) survivors..
Read MoreAbstract Objectives To evaluate whether prolonged exposure below a Patient State Index (PSI) threshold of 25—considered indicative of excessive anesthesia depth via processed electroencephalography—is associated with postoperative delirium (POD) in..
Read MoreAbstract Objective To evaluate whether neighborhood-level opportunity, measured by the Child Opportunity Index (COI), is associated with short- and long-term outcomes following pediatric extracorporeal membrane oxygenation (ECMO). Design Retrospective observational..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) is a type of mechanical circulatory support that is increasingly utilised for severe cardiorespiratory failure in the intensive care unit (ICU) setting. ECMO is..
Read MoreAbstract Background There is no universally accepted definition of perioperative blood loss in cardiac surgery. Existing methods are based on chest tube output and are not normalised for patient weight...
Read MoreAbstract Open thoracoabdominal aortic aneurysm repair (TAAAR) is associated with mortality rates of between 8% and 25%. One of the characteristics of TAAAR is massive bleeding that requires multiple units..
Read MoreAbstract Heparin-induced thrombocytopenia (HIT) in patients on mechanical circulatory support (MCS) prior to lung transplantation poses a unique challenge of balancing thrombotic versus hemorrhagic complications. An alternative method of anticoagulation..
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