Acute respiratory distress syndrome (ARDS) comprises 10–30% of critical care admissions worldwide [1]. ARDS outcomes have improved secondary to ventilatory strategies that may potentially mitigate ventilator-induced lung injury [2]. Interventions such as low tidal volume ventilation, minimization of the fraction of inspired oxygen (FiO₂), positive end-expiratory pressure titration, neuromuscular blockade, prone positioning, and facilitating “lung protection” with veno-venous extracorporeal membrane oxygenation (V–V ECMO) may have collectively improved mortality rates [3]. As the proportion of ARDS survivors has increased, recognition of the neurological sequelae in ARDS survivors has gained traction.