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Risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation support in adults based on the MIMIC-IV database

Abstract Objective:   To identify risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation (ECMO) support in adults and to develop a predictive model based on these factors...

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Extracorporeal life support for adult patients with ARDS

Abstract Extracorporeal Life Support (ECLS), including venovenous (VV) extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) is a temporary support option for patients with severe respiratory failure. Current..

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Incidence, kinetics, and clinical impact of thrombocytopenia in venovenous ECMO: insights from the multicenter observational PROTECMO study

Abstract Background Thrombocytopenia is a recognized risk factor for bleeding during extracorporeal membrane oxygenation (ECMO). This study determines the incidence, risk factors, and clinical relevance of thrombocytopenia and platelet transfusions..

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Storage duration of packed red blood cells transfused during veno-venous extracorporealmembrane oxygenation is associatedwith elevated pulmonary artery pressureand lung injury…

Abstract Background Veno‑venous extracorporeal membrane oxygenation (VV‑ECMO) is associated with a high transfusion burden. While trials have concluded that red blood cell (RBC) storage does not impact patient morbidity and..

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Crescent jugular dual-lumen catheter for adult veno-venous extracorporeal membrane oxygenation in China: Multicenter initial experience

Abstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a life support technique used for patients with life-threatening respiratory failure. It effectively addresses arterial hypoxemia without overstretching the injured lungs. Traditional..

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Pharmacological Research Agenda on Adult Extracorporeal Membrane Oxygenation Using the Delphi Method: A Position Article of the Extracorporeal Membrane Oxygenation…

Abstract Objectives:  Extracorporeal membrane oxygenation (ECMO) is a critical intervention for patients with severe cardiac or respiratory failure. However, pharmacological management for ECMO-supported patients presents unique challenges due to alterations..

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Optimal ECLS Support in Mixed Cardiogenic and Septic Shock: An ELSO Registry Analysis

Abstract Background Mixed cardiogenic and septic shock has been shown to have a higher mortality than cardiogenic shock alone and presents a unique hemodynamic phenotype. Objectives This study aimed to..

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Patients Post Cardiac Surgery Requiring Venoarterial Extracorporeal Membrane Oxygenation: Outcomes From an Intensivist-Led Extracorporeal Membrane Oxygenation Program

Abstract Post cardiac surgery shock (PCS) is a life-threatening condition that may require the use of mechanical circulatory support. Venoarterial (VA) extracorporeal membrane oxygenation (ECMO) is increasingly used to treat..

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Outcomes of Patients Requiring VA-ECMO for Cardiogenic Shock and Evaluation of Programmatic Changes

Abstract Objectives To describe outcomes in patients who received venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock and to evaluate outcomes following programmatic changes. Design A retrospective cohort study. Setting..

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Flow of Data, Not Blood Flow, Is the Key to Unraveling ECMO Support in Mixed Shock

Abstract Mixed shock has been identified by the Shock Academic Research Consortium (SHARC) as a “high-risk, understudied population”. It develops in around one-quarter of patients with cardiogenic shock and has a higher..

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Current intraoperative mechanical circulatory support strategies for bilateral lung transplantation surgery

Abstract Objective To discuss technical strategies and considerations to facilitate intraoperative extracorporeal membrane oxygenation (ECMO) management during lung transplantation. Methods We review our institutional approach to the management of intraoperative..

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Venovenous extracorporeal membrane oxygenation with mechanical chest compression for cardiopulmonary resuscitation: A porcine model study

Abstract Objective To evaluate the effectiveness of venovenous (VV) extracorporeal membrane oxygenation (ECMO) using a dual-lumen cannula coupled with continuous mechanical chest compressions (cMCC) for cardiopulmonary resuscitation and compare it..

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A Continuous, Real-Time Coagulation State Monitor for ECMO Patients

Abstract For patients undergoing extracorporeal membrane oxygenation (ECMO), clot formation is a critical complication requiring high-risk circuit changes. Blood tests used to assess clotting risk may be drawn only four..

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Red blood cell transfusion practices in extracorporeal membrane oxygenation: A single-center study

Abstract Objectives Evaluating blood transfusion practices and their impact on morbidity and mortality across extracorporeal membrane oxygenation (ECMO) configurations. Background As ECMO becomes increasingly utilised in critical care, the ideal..

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Investigation of contamination and environmental exposure of cold/heated water supply systems for extracorporeal circulation used in ECMO and other applications

Abstract Infection cases have been reported where Legionella spp. and NTM (non-tuberculous mycobacteria) increased due to the contamination of circulating water in cold/heated water supply systems for extracorporeal circulation used in cardiac..

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New Findings on Pulsatile ECMO: Verification of the Potential to Improve Antithrombogenicity of a Membrane Oxygenator Using Pump-Generated Pulsatile Flow…

Abstract Background Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory and respiratory support. However, thrombus formation in the circuit can lead to hemorrhagic complications, requiring improvements in ECMO anti-thrombogenicity. Few studies..

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Successful Treatment of Extracorporeal Membrane Oxygenation Induced Digital Ischemia in Infants Using Botulinum Toxin Type A

Abstract Digital ischemia following extracorporeal membrane oxygenation (ECMO) therapy is a known complication with potential devastating long-term sequela. Onabotulinum toxin type A (BTX-A) has been demonstrated to be effective for..

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Minimally invasive, transapical dual-lumened cannula for short-term left ventricular support in a clinically relevant large animal model†

Abstract OBJECTIVES Cardiogenic shock is still a major clinical challenge, despite the available devices. We developed a minimally invasive, transapical dual-lumened cannula, which can provide antegrade circulatory support and unloading..

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Is hyperoxia in early pediatric veno-veno extracorporeal life support associated with mortality?

Abstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and..

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Mortality and Complications in Hybrid Extracorporeal Membrane Oxygenation: A Meta-Analysis of Initial Use Versus Transition

Abstract Hybrid extracorporeal membrane oxygenation (ECMO), containing additional ECMO cannulations in addition to conventional ECMO, is increasingly used for the treatment of serious cardiopulmonary conditions. Patients initiating non-hybrid ECMO may..

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Critical hematological parameters in bleeding during extracorporeal membrane oxygenation support

Abstract Bleeding complications are frequently observed in patients undergoing extracorporeal membrane oxygenation and are associated with increased mortality. Due to the complex mechanisms, managing bleeding during ECMO remains a challenge...

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Comprehensive secondary analysis of thrombotic events in pediatric patients receiving extracorporeal membrane oxygenation: A prospective cohort study

Abstract Introduction This study aims to describe laboratory and clinical factors associated with thrombotic events during prolonged pediatric extracorporeal membrane oxygenation. Methods A secondary analysis of a multi-center prospective study..

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Veno-Arterial Extracorporeal Membrane Oxygenation in Cardiotoxic Drug-Induced Cardiogenic Shock: A Systematic Narrative Review

Abstract Background: Severe poisoning can lead to catastrophic cardiovascular collapse, often progressing to multiorgan failure and death. While intensive supportive care and pharmacological intervention remain the cornerstone of management, cases of..

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Cycle ergometers in extracorporeal membrane oxygenation patient rehabilitation: A scoping review

Abstract Introduction The aim of this scoping review was to determine what evidence is available regarding the use of the cycle ergometer in the rehabilitation of adult patients undergoing extracorporeal..

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Near-Infrared Spectroscopy for Preventing Limb Ischemia in Extracorporeal Membrane Oxygenation

Abstract Background Limb ischemia is a serious complication of venoarterial (VA) extracorporeal membrane oxygenation (ECMO), potentially resulting in amputation, rhabdomyolysis, or death. This study aimed to evaluate the effectiveness of..

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Total thyroidectomy performed under general anesthesia with venovenous extracorporeal membrane oxygenation during a thyroid storm: a case report

Abstract Thyroid storm (TS) is an endocrine emergency requiring aggressive medical management. In severe cases, hemodynamic instability may necessitate extracorporeal membrane oxygenation (ECMO) support as a bridge to definitive surgical..

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Redefining weaning in a VA ECMO: a case report on pump-controlled retrograde trial off

Abstract Extracorporeal membrane oxygenation (ECMO) is widely recognized as a life-saving measure. The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is on the rise, serving as an effective mechanical..

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Visualizing Flow Dynamics in a Human Aorta During Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Treatment Through Particle Image Velocimetry Study

Abstract Purpose To build a mock circulatory loop to simulate veno-arterial extracorporeal membrane oxygenation (V-A ECMO) haemodynamics using a patient-specific silicone aortic phantom and compare the flow dynamics for continuous..

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The Impact of the COVID-19 Pandemic on Intensive Care Nurses' Experience in Providing Extracorporeal Membrane Oxygenation Care

Abstract To explore the challenges and describe the impact of the COVID-19 pandemic on intensive care nurses' experience in providing ECMO care in a high-volume Australian ICU ECMO centre that..

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Heparin-free veno-venous ECMO for airway obstruction: A case report and review of literature

Abstract Rationale:  Life-threatening airway obstructions caused by tumors demand prompt and effective intervention. Traditional surgical methods are often complicated by bleeding risks, especially with the use of anticoagulation during extracorporeal..

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