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Parallel Dual-Lumen Venovenous Extracorporeal Membrane Oxygenation Following Extracorporeal Cardiopulmonary Resuscitation

Abstract Differential oxygenation may complicate extracorporeal cardiopulmonary resuscitation (ECPR) either due to the initial pathology or subsequent lung injury. The dual circulation phenomenon inherent to peripheral venoarterial extracorporeal membrane oxygenation..

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Elective Use of Veno-Venous Extracorporeal Membrane Oxygenation to Support Complex Surgery Involving the Central Airways

Abstract Introduction Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supports oxygenation and carbon dioxide (CO2) clearance in the short- or mid-term, and is traditionally utilized in severe, refractory respiratory failure. There is..

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Epidemiology of nosocomial infections in ECMO patients in Qatar: the CLEAN-Q seven-year retrospective cohort study

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) is a critical rescue therapy complicated by high rates of nosocomial infections (NIs). While Western data abound, evidence from the Middle East remains limited...

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Early Postoperative Mitral Bioprosthetic Thrombosis During ECMO Support: Urgent Transcatheter Valve-in-Valve Implantation

Abstract Acute postoperative bioprosthetic valve thrombosis is a rare complication with challenging treatment. We present two consecutive cases of patients with myocardial infarction and papillary muscle rupture requiring urgent surgical..

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In-Hospital Mortality Prediction of Patients Requiring Extracorporeal Membrane Oxygenation Using Composite Lactate Metrics and Weight-of-Evidence Modeling

Abstract BACKGROUND:  Mortality prognostication in adult patients requiring extracorporeal membrane oxygenation (ECMO) is not accurate or established. We hypothesized that composite lactate-based metrics and machine-learning models would improve in-hospital mortality..

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Introducer–Cannula Diameter Mismatch and Difficult Veno-Venous Extracorporeal Membrane Oxygenation Cannulation: A Case Report

Abstract Obesity poses technical challenges during veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannulation because of thick subcutaneous tissue and increased insertion resistance. While patient-related factors are well recognized, the impact of..

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Hospital Costs Associated With Mechanical Left Ventricular Unloading Devices During VA ECMO for Adult Cardiogenic Shock

Abstract Importance To date, no studies have described the financial burden and behaviors of left ventricular mechanical unloading (LVMU) for patients on veno-arterial extracorporeal membrane oxygenation (VA ECMO). Given the..

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Differential hypercapnia: Recognition, management, and outcomes in an awake patient supported with peripheral veno-arterial extracorporeal membrane oxygenation

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving intervention for individuals with refractory cardiopulmonary failure and is associated with several complications. Differential hypercapnia, also known as RIDDLER syndrome or..

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Markers of inflammation and immunological competence: Assessment in the early postoperative phase of cardiac surgery involving extracorporeal circulation

Abstract Background To gain insight into the role and relevance of inflammatory and immunological markers in the comprehensive assessment of a patient's immune response to surgical procedures. This study focused..

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Clinical correlates for major bleeding during veno-arterial extracorporeal membrane oxygenation support: a time-dependent perspective

Abstract Background Major bleeding is a common and serious complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO). Current perspectives on bleeding risk fail to reflect dynamic changes over time in..

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Continuous vs pulsatile arterial cannula flow for venoarterial extracorporeal membrane oxygenation: A multiscale computational fluid dynamics analysis

Abstract Background and Objective Venoarterial extracorporeal membrane oxygenation (VA ECMO) circuits typically utilise a continuous flow (CF) of blood to support patients suffering from refractory cardiorespiratory dysfunction. Pulsatile flow (PF)..

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Semi-Empirical Model to Predict Blood Flow in an Extracorporeal Respiratory Support Circuit Driven by Ventricular Assist Devices

Abstract Despite increasing clinical interest in ambulatory extracorporeal membrane oxygenation (ECMO), its equipment is not optimally designed for portability. Blood pumps are too heavy for ambulation, as the lightest system..

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Acid–Base Status During Venoarterial Extracorporeal Membrane Oxygenator Support in Patients With Cardiogenic Shock

Abstract Background The prognostic significance of an adverse acid–base milieu despite venoarterial extracorporeal membrane oxygenation support in patients with cardiogenic shock remains poorly defined. We examined metabolic and respiratory disturbances..

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Standardization of In Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development

Abstract Extracorporeal life support (ECLS) technology has witnessed remarkable advancements during the last decades. However, further research and development of devices are required to increase, for example, performance-efficiency, hemocompatibility, and..

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A Landmark Case in ECMO-Supported Bridge-to-Transplant Care

A Landmark Case in ECMO-Supported Bridge-to-Transplant Care  Extracorporeal membrane oxygenation (ECMO) has always been a therapy defined by its ability to buy time; time for a heart to recover, for lungs..

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Effect of ECMO Flow Variations on Pulmonary Capillary Wedge Pressure in Patients With Cardiogenic Shock

Abstract Background The hemodynamic effects of femoro-femoral venoarterial (VA) extracorporeal membrane oxygenation (ECMO) on pulmonary capillary wedge pressure (PCWP) remain poorly defined. High ECMO flow is believed to increase PCWP..

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Evaluation of bivalirudin-based anticoagulation for extracorporeal membrane oxygenation, including patients with COVID-19

Abstract Background: Although unfractionated heparin (UFH) has traditionally been used for anticoagulation during extracorporeal membrane oxygenation (ECMO), bivalirudin may be preferred due to fewer complications. A prior medication use evaluation..

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Clinician Perspectives on the Extracorporeal Membrane Oxygenation Decision-Making Process

Abstract Importance  Venovenous extracorporeal membrane oxygenation (VV ECMO) is a resource-intensive, life-sustaining technology to support patients with severe refractory respiratory failure. Its precise indications and contraindications are not standardized, and expert..

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Management of the environment and patient care using extracorporeal membrane oxygenation: A scoping review

Abstract Introduction The use of strategies planned for the environment and care of adult patients undergoing Extracorporeal Membrane Oxygenation allows for better assistance from the multidisciplinary team to this individual..

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Nanoconjugated anticoagulant coating with blood repellency for extracorporeal circulation in cardiothoracic surgery

Abstract Coating strategies play a pivotal role in anticoagulation management during extracorporeal circulation. While heparin-based coatings remain the most widely used, their limited anticoagulant efficacy may lead to adverse events..

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The Role of Extracorporeal Membrane Oxygenation in Airway Surgery: Experience From a French Referral Centre for Tracheobronchial Diseases Get access…

Abstract Objectives In complex airway surgery and high-risk rigid bronchoscopy, conventional ventilation may be unsafe or impossible. We report our experience using veno-venous extracorporeal membrane oxygenation (VV-ECMO) as respiratory support...

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Simple and reliable method for predicting extracorporeal membrane oxygenation flow rates and circuit pressures

Abstract Background Venovenous extracorporeal membrane oxygenation (ECMO) is essential for patients with severe respiratory failure who do not respond to conventional mechanical ventilation. Adequate ECMO flow and safe circuit pressure..

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Noninvasive Predictive Model for Rapid Hemodynamic Optimization During Mechanical Circulatory Support

Abstract Mechanical circulatory support (MCS) devices are standard therapy for advanced heart failure, but modern systems lack standardized methods for setting critical parameters such as rotational speed and flow rate...

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Integration Health Guides Hospitals in Advanced Circulatory Support Through ECMO and Perfusion Educational Resources

Abstract Hospitals seeking to implement complex technologies like extracorporeal membrane oxygenation (ECMO) now have practical roadmaps thanks to Integration Health’s effort to provide guidance drawn from decades of clinical and..

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Prolonged Extracorporeal Membrane Oxygenation Without Systemic Anticoagulation in Sheep

Abstract Clinically significant bleeding is a common complication of extracorporeal membrane oxygenation (ECMO), with bleeding observed in upwards of 40% of patients. Bleeding is strongly associated with systemic anticoagulation, which..

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Balancing flow and filtration: AKI during ECMO

Abstract Acute Kidney Injury (AKI) cannot be viewed as a mere complication in critically ill patients who require extracorporeal membrane oxygenation (ECMO). Rather, it is being increasingly recognized as an..

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Venoarterial Extracorporeal Membrane Oxygenation Drainage Cannula Choice Impacts Flow Dynamics and Thrombosis Risk: A Computational Analysis

Abstract The drainage cannula in a venoarterial extracorporeal membrane oxygenation (VA ECMO) circuit transfers venous blood from the patient to a pump. However, drainage cannulas are prone to thrombosis, leading..

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Net Prolongation of Life in Advanced Heart Failure: An Intentional Strategy of Durable LVAD Therapy Followed by Heart Transplantation

Abstract Heart transplantation (HT) and durable left ventricular assist device (LVAD) support are established surgical treatment options for patients with end-stage systolic heart failure (HF) and/or nonrecoverable cardiogenic shock. HT..

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Association of VA-ECMO support and long-term quality of life after post-cardiotomy cardiogenic shock: experience from a prospective cohort

Abstract Post-cardiotomy cardiogenic shock (PC-CS) affects 2–6% of cardiac surgery patients. While survival rates keep improving, 40% of intensive care (ICU) survivors experience a “post-intensive care syndrome”, encompassing physical, cognitive,..

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Evidence-based guidelines for the use of extracorporeal membrane oxygenation in Australia and New Zealand using GRADE methodology series part 1:…

Abstract We aim to provide evidence-based clinical practice guidelines for the use of VV ECMO in adult patients across Australia and New Zealand. Developed by a multidisciplinary panel of clinicians..

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