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Perfusfind S.L.

Abstract Background Sex-based differences in outcomes after cardiac surgery are consistently reported, with women frequently experiencing higher postoperative morbidity and mortality. While emerging evidence suggests that patient-physician sex concordance may..

Perfusfind S.L.

Abstract Background While cardiac surgery and cardiopulmonary bypass (CPB) are on rise, postoperative infections have become an increasingly prominent problem. We designed this study to compare the four coagulation indicators..

Perfusfind S.L.

Abstract Hemolysis, the rupture of red blood cells, releases hemoglobin, haem, and redox-active iron into the bloodstream. When the body’s scavenging capacity is overwhelmed, these species can exert deleterious effects,..

Perfusfind S.L.

Abstract Objectives To evaluate postoperative residual and reappearing heparin activity after low-dose, titration-guided protamine reversal following cardiopulmonary bypass (CPB) in elective coronary artery bypass grafting (CABG). Design Prospective, controlled clinical..

Perfusfind S.L.

Abstract Background: The aim of this study was to assess the long-term outcomes of patients treated with intra-aortic balloon pump (IABP) alone and in combination with extracorporeal membrane oxygenation (ECMO),..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass (CPB) is essential in open-heart surgery but is associated with systemic inflammatory response syndrome and organ-specific complications, which can worsen patient outcomes. In low-resource settings, limited..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) remains one of the most frequent complications after cardiac surgery and is associated with nearly 40% mortality at 5 years (). These concerning outcomes have..

Perfusfind S.L.

Abstract Cardiac surgery-associated acute kidney injury (CSA-AKI) is a frequent and severe complication of open-heart surgery. Although oxidative/inflammatory mechanisms are known to contribute to its pathophysiology, the circulating factors involved..

Perfusfind S.L.

Abstract In a randomized controlled trial, Jain et al. () demonstrated that administration of a fixed 250 mg dose of protamine following cardiopulmonary bypass (CPB) resulted in lower total protamine dose compared..

Perfusfind S.L.

Abstract Background Neonatal cardiac surgery is associated with high morbidity and mortality. Perioperative metabolic stress may result in distinct metabolic phenotypes associated with adverse clinical outcomes. Objectives The purpose of..

Perfusfind S.L.

Abstract High-pressure excursions (HPE) during cardiopulmonary bypass (CPB) are rare but potentially life-threatening events linked to coagulation activation, inflammation. Known risk factors include male sex, large body surface area (BSA),..

Perfusfind S.L.

Abstract Objectives To compare myocardial protection afforded by three single-dose cardioplegic solutions — Custodiol (HTK), del Nido (DN) and modified del Nido (MDN) — in adult elective cardiac surgery. Design Double-blind randomised..

Perfusfind S.L.

Abstract Objective: To describe surgical outcomes, in-hospital mortality, and variables associated with mortality in pediatric patients with congenital heart disease (CHD) at a national referral center in México over 14..

Perfusfind S.L.

Abstract BACKGROUND: Vasoplegic shock is distributive shock that follows cardiopulmonary bypass, characterized by hypotension, low systemic vascular resistance, and catecholamine resistance despite preserved or elevated cardiac output. Reported incidence ranges..

Perfusfind S.L.

Abstract BACKGROUND: Fibrinogen/albumin ratio (F/A ratio) has been proposed as a prognostic factor for different outcomes in different clinical settings, including cardiovascular interventions. However, few studies address the F/A ratio..

Perfusfind S.L.

Abstract Background/Objectives: Postoperative complications following adult cardiac surgery are biologically interrelated, yet most machine learning models predict single outcomes. We developed an explainable multi-output model integrating routinely collected clinical variables..

Perfusfind S.L.

Abstract Importance  Cyanotic congenital heart diseases, which occur in approximately 0.2% of live births in the United States, have high mortality rates if untreated, but survival to adulthood is common with..

Perfusfind S.L.

Abstract Postoperative cognitive dysfunction (POCD) is a frequent complication of cardiac surgery. The present study aimed to quantify changes in Mini‑Mental State Examination (MMSE) scores following on‑pump cardiac surgery and..

Perfusfind S.L.

Abstract Background: Discussions continue on the ideal priming fluid in adult cardiac surgery. The purpose of this prospective study was to evaluate the effects of different types of priming fluids..

Perfusfind S.L.

Abstract Aortic manipulation and prolonged ischemia during cardiopulmonary bypass remain major drivers of perioperative complications. Optimizing clamping strategies is crucial to minimize iatrogenic blood loss and improve recovery profiles within..

Perfusfind S.L.

Abstract This “Pro” argument supports the routine incorporation of point-of-care viscoelastic testing (VET) into perioperative bleeding management algorithms for all cardiac surgery patients. This group of patients remains among the..

Perfusfind S.L.

Abstract Introduction Uncertainty remains regarding whether the time of day that cardiac surgery is performed affects postoperative outcomes or if the observed variation can be explained by patient or surgical..

Perfusfind S.L.

Abstract Traditional methods of heart transplantation utilizing allografts from donors after circulatory death (DCD) involve 2 periods of ischemia and 2 ischemia reperfusion injuries (IRI). Both ischemia and IRI are..

Perfusfind S.L.

Abstract Conventional cardiopulmonary bypass (cCPB) remains fundamental to modern cardiac surgery, yet its associated hemodilution, blood–air interaction, inflammatory activation, coagulation disturbance, and microembolic burden continue to affect perioperative organ protection..

Perfusfind S.L.

Abstract Background Female patients have a higher incidence and greater severity of neurocognitive decline (NCD) after cardiac surgery. We investigated whether sex hormones play a role in this difference. Methods..

Perfusfind S.L.

Abstract Objective Postoperative acute kidney injury (AKI) after cardiac surgery is a major complication that worsens patient outcomes and increases healthcare costs. This study aimed to investigate the association between..

Perfusfind S.L.

Abstract Neurological injury remains a major concern during neonatal aortic arch surgery. Near-infrared spectroscopy (NIRS) is commonly used to monitor cerebral oxygenation but does not provide direct quantitative information on..

Perfusfind S.L.

Abstract A critical aspect of cardiopulmonary bypass (CPB) is achieving full anticoagulation to prevent thrombosis and consumptive coagulation (CCA). Systemic anticoagulation with heparin during CPB should be completely neutralized by..

Perfusfind S.L.

Abstract Background Preoperative intravenous iron has become increasingly popular as a strategy to optimize hemoglobin before major surgery. However, its potential benefit in non-anaemic patients undergoing cardiac surgery remains unclear...

Perfusfind S.L.

Abstract Background Optimal oxygenation strategies during cardiopulmonary bypass (CPB) in children with cyanotic congenital heart disease remain controversial. Although hyperoxia has traditionally been used to compensate for chronic hypoxemia, concerns..