Abstract While extracorporeal membrane oxygenation (ECMO) case volume continues to increase [, ], management of patients receiving ECMO remains technically challenging [, ]. Iatrogenic injury is a potential contributor to complications and..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (ECPR) offers a life-saving option for select patients with refractory cardiac arrest, yet a substantial proportion suffer devastating neurological injury and die despite extracorporeal support. In..
Read MoreAbstract Purpose Pediatric patients undergoing cardiac surgery are at risk of developing postoperative acute kidney injury (AKI). We hypothesized that a reduction in intraoperative renal (SrO2) or cerebral (ScO2) tissue..
Read MoreAbstract Background Extracorporeal Life Support (ECLS) services are characterised by variability in resource availability, specific expertise, device management and team organisation, especially regarding the role of perfusionists. This international survey..
Read MoreAbstract Background We implemented a preoperative screening brain magnetic resonance imaging (MRI) protocol for neonates undergoing cardiac surgery. The intent was to identify unrecognized central nervous system (CNS) injury that..
Read MoreEarly colonoscopy for detection of colon ischemia after extracorporeal cardiopulmonary resuscitation
Abstract Dear Editor, Extracorporeal cardiopulmonary resuscitation (ECPR) refers to the initiation of venoarterial extracorporeal membrane oxygenation (VA ECMO) during cardiac arrest to restore systemic perfusion with oxygenated blood []. Prolonged..
Read MoreAbstract Cerebrovascular autoregulation maintains stable cerebral blood flow by counteracting slow changes in cerebral perfusion pressure (termed “slow waves”). Conventional assessment involves invasive techniques using intracranial pressure (ICP) or technically..
Read MoreAbstract Background We have demonstrated cardioprotection by the adenosine triphosphate–sensitive potassium (KATP) channel opener diazoxide in multiple animal models in an effort to reduce myocardial stunning following cardiac surgery. These..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized for life-threatening cardiac and/or respiratory failure refractory to conventional treatment. Acute kidney injury (AKI) and fluid balance disorders commonly occur both..
Read MoreAbstract Background: Sanguineous preparation of the cardiopulmonary bypass (CPB) circuit with allogeneic blood products is known to contain substantial complement mediator burden. This study aims to assess the longitudinal immunologic impacts..
Read MoreAbstract Background Despite advances in cardiopulmonary resuscitation (CPR), survival after out-of-hospital cardiac arrest (OHCA) remains low. Use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) as extracorporeal CPR (ECPR) may improve..
Read MoreAbstract The role of intra-aortic balloon pump (IABP) use in optimizing patients for durable left ventricular assist device (LVAD) implantation is being reevaluated in the era of modern centrifugal, magnetically..
Read MoreAbstract Objectives Postcardiopulmonary bypass bleeding is frequent and distinctive because of its associated coagulopathy. Despite diagnostic and therapeutic progress, substantial variability persists in hemostatic transfusion practices. Because transfusion of hemostatic..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) provides lifesaving support for patients with cardiopulmonary failure but poses complex ethical challenges that may generate moral distress for clinicians, patients, and families. We convened..
Read MoreAbstract Importance Acute respiratory distress syndrome (ARDS) represents a frequent and serious complication after cardiovascular surgery. Although sivelestat, a specific neutrophil elastase inhibitor, has demonstrated therapeutic potential in preliminary studies, the..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is widely used in patients with severe cardiac or respiratory failure. ECMO is resource and cost intensive and carries the potential for significant complications; therefore,..
Read MoreAbstract Introduction Survival after out-of-hospital cardiac arrest (OHCA) remains poor, particularly for refractory ventricular fibrillation/ventricular tachycardia (VF/VT). Extracorporeal cardiopulmonary resuscitation (ECPR) improves outcomes when delivered within 60 minutes of low-flow..
Read MoreAbstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a complex and invasive intervention used increasingly in the management of severe respiratory failure. Once established, the management of prolonged V-V ECMO..
Read MoreAbstract Importance Underweight and obesity represent opposite ends of the nutritional risk spectrum that negatively affect children’s health worldwide. Both conditions have been associated with increased mortality in pediatric patients receiving..
Read MoreAbstract Ventricular septal rupture (VSR) is a rare but often fatal complication of acute myocardial infarction (AMI), with a high mortality largely driven by resultant cardiogenic shock. Venoarterial extracorporeal membrane..
Read MoreAbstract Normothermic regional perfusion (NRP) is increasingly implemented to optimize the outcome of transplantation from donors undergoing circulatory determination of death. NRP shortens the duration of warm ischemia, allowing splanchnic..
Read MoreAbstract Disseminated intravascular coagulation (DIC) has long been described as a catastrophic systemic activation of coagulation with suppressed anticoagulant and fibrinolytic pathways, culminating in macro- and microvascular thrombosis, hypoperfusion, and..
Read MoreAbstract Background This study evaluates the outcomes and management considerations associated with using extracorporeal membrane oxygenation (ECMO) in patients with traumatic brain injury (TBI), including those requiring neurosurgical intervention. It..
Read MoreAbstract A clear and systematic terminological framework is essential for exactly describing a patient’s hemodynamic state. After assessing absolute values of hemodynamic variables and considering the specific clinical context, the..
Read MoreAbstract Background Protected cardiac surgery is a proactive strategy that applies temporary mechanical circulatory support to prevent perioperative low cardiac output syndrome in high-risk cardiac surgery. Rather than escalating vasoactive..
Read MoreAbstract Background Bleeding and thrombosis are major complications of micro-axial flow pump (mAFP) support in cardiogenic shock (CS), yet contemporary data on their incidence, temporal trends, and prognostic impact remain..
Read MoreAbstract Anticoagulants are widely used to prevent and treat thrombotic disorders, and continuous advances have refined their efficacy and safety. Beyond their established anticoagulant function, growing evidence indicates that some..
Read MoreAbstract Intractable bleeding during cardiac surgery is a rare but life-threatening complication. We describe a novel management approach in which the patient was supported with venoarterial extracorporeal membrane oxygenation until..
Read MoreAbstract Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion..
Read MoreAbstract Differential oxygenation may complicate extracorporeal cardiopulmonary resuscitation (ECPR) either due to the initial pathology or subsequent lung injury. The dual circulation phenomenon inherent to peripheral venoarterial extracorporeal membrane oxygenation..
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