Archives

Perfusfind S.L.

Abstract Historically, extracorporeal membrane oxygenation (ECMO) in critical illness and respiratory failure has been used cautiously in patients with morbid obesity. However, recent data show favorable mortality outcomes for higher..

Perfusfind S.L.

Abstract Background Venous thromboembolism (VTE) is a common complication following lung transplantation, and perioperative extracorporeal membrane oxygenation (ECMO) use has increased substantially over time. The relationship between ECMO exposure and..

Perfusfind S.L.

Abstract BACKGROUND: Individuals who survive acute respiratory distress syndrome (ARDS) often face prolonged cognitive impairments. Comparable consequences have been observed in chronic hypoxic conditions, like COPD and obstructive sleep apnea..

Perfusfind S.L.

Abstract Background Cardiac surgery associated acute kidney injury (CSA-AKI) is a common and serious complication following cardiac surgery with cardiopulmonary bypass (CPB), associated with prolonged hospitalization, increased costs, and higher..

Perfusfind S.L.

Abstract Patients supported with extracorporeal membrane oxygenation (ECMO) represent a uniquely challenging population. These patients require specific interventions, such as repeated circuit and lower extremity perfusion assessments, anticoagulation management, frequent..

Perfusfind S.L.

Abstract Objectives Recent randomized controlled trials comparing extracorporeal cardiopulmonary resuscitation (ECPR) with conventional cardiopulmonary resuscitation (CCPR) reveal mixed outcomes; however, current data support an association between ECPR and neurologically intact..

Perfusfind S.L.

Abstract Lactate clearance is a key marker of oxygen delivery after neonatal cardiac surgery. While higher hematocrit (HCT) is often targeted to optimize oxygen delivery, its relationship with postoperative lactate..

Perfusfind S.L.

Abstract Awake extracorporeal membrane oxygenation (aECMO) has emerged as a strategy to minimise physical and neurocognitive complications of a prolonged intensive care admission. However, the safety and implementation in critically..

Perfusfind S.L.

Abstract The International Society on Thrombosis and Haemostasis (ISTH) recently published a survey on the management of unfractionated heparin (UFH), which revealed substantial heterogeneity in practice and highlighted the need..

Perfusfind S.L.

Abstract Existing risk stratification methods in cardiothoracic surgery do not use pre-operative bicarbonate levels. We investigate if these levels carry predictive value when compared with demographic, hematologic, and other renal..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) is increasingly used in adults with severe respiratory and/or cardiac failure. Because ECMO may alter drug pharmacokinetics (PK), optimizing antimicrobial dosing in this population..

Perfusfind S.L.

Abstract Objectives Comparing clinical outcomes after cardiopulmonary bypass with hemodsorption (HA) versus cardiopulmonary bypass without HA in patients undergoing cardiac surgery in terms of mortality and major complications. Methods PubMed,..

Perfusfind S.L.

Abstract Objectives To explore the superiority of fibrinogen concentrate (FC) versus cryoprecipitate for bleeding after cardiac surgery. Design Secondary analysis of the FIBRES randomized trial. Setting Eleven Canadian hospitals, February..

Perfusfind S.L.

Abstract Background Acute myocardial infarction complicated by cardiogenic shock (AMI-CS) carries a high risk of in-hospital death. Randomized evidence does not support routine VA-ECMO use in unselected AMI-CS populations. Objective..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving modality, yet it carries inherent risks of device-related adverse events. This manuscript is a focused review of ECMO circuit mechanics, monitoring, and..

Perfusfind S.L.

Abstract Cardiac surgery-associated acute kidney injury (CSA-AKI) is a prevalent complication subsequent to cardiopulmonary bypass (CPB) surgery. Timely diagnosis is essential for enhancing patient outcomes. Traditional diagnostic approaches that depend..

Perfusfind S.L.

Abstract Background In mitral valve surgery, cardioplegia is commonly dosed by body weight or body surface area (BSA), which may not reflect true cardiac mass. We evaluated whether indexing the..

Perfusfind S.L.

Abstract Background Severe hyperoxia during venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been associated with adverse clinical outcomes in observational studies. However, causal evidence and optimal oxygen targets remain uncertain. Hyperoxia..

Perfusfind S.L.

Abstract Background: Cardiopulmonary bypass (CPB) during cardiac surgery poses physiological challenges such as altered drug pharmacokinetics. Sevoflurane, a commonly used volatile agent, provides favorable myocardial protection; however, precise dosing during..

Perfusfind S.L.

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA ECMO) provides temporary mechanical circulatory support, primarily for patients with compromised cardiac function. In individuals supported on femoral VA ECMO with concurrent pulmonary..

Perfusfind S.L.

Abstract Background The efficiency of venovenous extracorporeal membrane oxygenation (VV ECMO) may be influenced by cannula configuration, potentially affecting oxygenation and the ability to apply ultra-protective ventilation in severe ARDS...

Perfusfind S.L.

Abstract Failure to wean from cardiopulmonary bypass (CPB) is a rare but critical intraoperative challenge. Common causes include residual structural defects (causing intracardiac shunting, prosthetic valve leaks), left ventricle outflow..

Perfusfind S.L.

Abstract Background Optimal timing of venoarterial extracorporeal membrane oxygenation (VA-ECMO) decannulation in pediatric patients with congenital or acquired heart disease remains challenging, particularly when myocardial recovery is uncertain. Some centers..

Perfusfind S.L.

Abstract Background Cardiac arrest impacts more than 500,000 people in the United States annually. Overall, cardiac arrest, particularly when it occurs outside of a hospital, is associated with low rates..

Perfusfind S.L.

Abstract Factor XIII (FXIII) is the final enzyme in the coagulation cascade that cross-links the fibrin monomers, thereby enhancing the clot strength. Congenital FXIII deficiency is rare and is inherited..

Perfusfind S.L.

Abstract Objective Acute kidney injury (AKI) complicates pediatric cardiac surgery, particularly in single-ventricle palliation. While retrograde lower body perfusion (LBP) has been associated with a renal-protective signal during aortic arch..

Perfusfind S.L.

Abstract In recent years, artificial placenta systems have been developed for the clinical treatment of infant respiratory distress syndrome (RDS). Their use requires systemic anticoagulation to prevent clotting during treatment...

Perfusfind S.L.

Abstract Background: Hemolytic complications remain a major limitation of membrane oxygenators in clinical support. Compared with human lungs, most commercial oxygenators generate substantial pressure drops and high shear stress, increasing..

Perfusfind S.L.

Abstract Background Patients receiving clopidogrel who undergo urgent CABG before the recommended 5-day washout period are at increased risk of perioperative bleeding. This study evaluated whether intraoperative hemoadsorption can reduce..

Perfusfind S.L.

Abstract Objective: Cardiac surgery carries a significant risk of complications and mortality. Artificial intelligence (AI), particularly machine learning (ML), is increasingly being explored to enhance perioperative risk prediction and support..