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Cerebral Oximetry-Monitored Nitroglycerin Infusion and Tissue Perfusion during Rewarming of Cardiopulmonary Bypass in Cardiac Surgery: A Prospective Randomized Trial

Abstract Background: Nitroglycerin facilitates microcirculation and oxygen delivery through vasodilation. The purpose of this study was to clarify the effects of nitroglycerin-induced vasodilation and potential hypotension on tissue perfusion under..

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Case Report of a Successful Pediatric Central Venovenous Extracorporeal life Support via Right Atrium-Pulmonary Artery Cannulation for Severe Chest Trauma…

Abstract Hypoxemic arrests due to severe traumatic pulmonary injury may not respond to usual medical support. Extracorporeal life support (ECLS) can be life-saving; adequate flows are needed in this setting..

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Measuring the Resting Energy Expenditure in Children on Extracorporeal Membrane Oxygenation: A Prospective Pilot Study

Abstract Both overfeeding and underfeeding critically ill children are problematic. This prospective pilot study evaluated the resting energy expenditure in infants and children requiring extracorporeal membrane oxygenation (ECMO) support. An..

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Pump-controlled retrograde trial off for weaning from adult veno-arterial extracorporeal membrane oxygenation – a retrospective observation cohort

Abstract Background The optimal strategy of weaning veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) remains poorly described. Pump-controlled retrograde trial off (PCRTO) involves serial decremental pump revolutions until a retrograde flow..

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How to avoid rapid carbon dioxide changes at the start of veno-venous extracorporeal membrane oxygenation: Role of end-tidal CO2 monitoring

Abstract Background: Venovenous ECMO is a lifesaving technique for patients with severe respiratory failure. Management of carbon dioxide (CO2) levels at ECMO start is crucial, as recent studies found an association..

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Initial results from an enhanced recovery program for pediatric cardiac surgical patients

Abstract Background Over recent years, a number of enhanced recovery programs have appeared in first, adult colorectal surgery, and subsequently many other adult surgical specialties. Increasing interest in this approach..

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Validation of the Masimo O3™ regional oximetry device in pediatric patients undergoing cardiac surgery

Abstract We assessed the accuracy of Masimo O3™ regional cerebral oxygen saturation (rSO2) readings by comparing them with reference values and evaluated the relationship between rSO2 and somatic tissue oxygen saturation..

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Hemodynamic oxygenator exchange-related effects during veno-venous extracorporeal membrane oxygenation for the treatment of acute SARS-CoV-2 respiratory distress syndrome

Abstract Few patients with coronavirus disease 2019–associated severe acute respiratory distress syndrome (ARDS) require veno-venous extracorporeal membrane oxygenation (VV-ECMO). Prolonged VV-ECMO support necessitates repeated oxygenator replacement, increasing the risk for..

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Platelet Dysfunction in Cardiac Surgery: When is the Best Time to Assess It? An Observational Single Center Study

Abstract Purpose. Cardiac surgery is characterized by a high risk of complications related to perioperative bleeding. Guidelines suggest the use of local algorithms based on perioperative point-of-care tests to assess and..

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The Association Between Angiotensin II and Renin Kinetics in Patients After Cardiac Surgery

Abstract BACKGROUND:  Hyperreninemia after cardiac surgery is associated with cardiovascular instability. Angiotensin II (AT-II) could potentially attenuate hyperreninemia while maintaining target blood pressure. This study assesses the association between AT-II..

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Does the Volume and Constitution of Cardiopulmonary Bypass Priming Fluids Affect Blood Loss After Cardiac Surgery in Children?

Abstract Pediatric patients, especially neonates and infants, undergoing cardiac surgery, are at particularly high risk for developing surgical bleeding. After separation from cardiopulmonary bypass (CPB), excessive bleeding in children frequently..

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When Veno-Venous ECMO Recirculation Counts

Over the last two years, Extracorporeal Membrane Oxygenation (ECMO) has emerged as a therapy for COVID-related Acute Respiratory Distress Syndrome (ARDS) and continues to be a successful therapy for ARDS..

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Prospective study of preoperative autologous blood donation for patients with high risk of allogeneic blood transfusion in lumbar fusion surgery:…

Abstract Introduction Preoperative autologous blood donation (PABD) can be used to reduce the exposure of allogeneic blood transfusion in patients undergoing elective surgery. Better blood management to avoid anaemia and reduce..

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38th Annual Children’s National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure.

Abstract Introduction: Pediatric extracorporeal membrane oxygenation (ECMO) is a high risk, low-volume technology. Infrequency of this technology and associated complications may translate to unfamiliarity of identification and management of potentially..

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Association of Ventilator Settings with Mortality in Pediatric Patients Treated with Extracorporeal Life Support for Respiratory Failure

Abstract Extracorporeal life support (ECLS) is a treatment for acute respiratory failure that can provide extracorporeal gas exchange, allowing lung rest. However, while most patients remain mechanically ventilated during ECLS,..

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Viscoelastic Hemostatic Assays: A Primer on Legacy and New Generation Devices

Abstract Viscoelastic hemostatic assay (VHAs) are whole blood point-of-care tests that have become an essential method for assaying hemostatic competence in liver transplantation, cardiac surgery, and most recently, trauma surgery..

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Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress

Abstract Heart disease requires a surgical approach sometimes. Cardiac-surgery patients develop heart failure associated with ischemia induced during extracorporeal circulation. This complication could be decreased with anesthetic drugs. The cardioprotective..

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Admission blood glucose level and outcome in patients requiring venoarterial extracorporeal membrane oxygenation

Abstract Background Patients with cardiogenic shock or cardiac arrest undergoing venoarterial extracorporeal membrane oxygenation (V-A ECMO) frequently present with blood glucose levels out of normal range. The clinical relevance of..

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Extracorporeal membrane oxygenation in coronavirus disease 2019

Abstract BACKGROUND  In the context of the coronavirus disease 2019 (COVID-19) pandemic, many retrospective single-centre or specialised centre reports have shown promising mortality rates with the use of extracorporeal membrane..

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The Myocardial Protective Effects of a Moderate-Potassium Blood Cardioplegia in Pediatric Cardiac Surgery: A Randomized Controlled Trial

Abstract Background We investigated the myocardial protective effect of a moderate-potassium cold blood cardioplegic solution (K+, 10 mmol/L) in pediatric cardiac surgery. Methods Sixty-eight pediatric patients with congenital heart disease..

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Stone heart syndrome after prolonged cardioplegia induced cardiac arrest in open-heart surgery – a pilot study on pigs

Abstract OBJECTIVES : To investigate Stone Heart Syndrome (SHS) as consequence of prolonged ischemic arrest in an experimental study on pigs in regards to onset of SHS and pathological changes...

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A six-year study of complications related to peripherally inserted central catheters: A multi-center retrospective cohort study in China

Abstract Objective Peripherally inserted central catheters (PICCs), the most frequent central venous catheter, are used to provide medical treatments, although long-term PICC-related adverse outcomes are unknown in China. This study..

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Oxygenator impact on peramivir in extra-corporeal membrane oxygenation circuits

Abstract Introduction This study aims to determine the oxygenator impact on alterations of peramivir (PRV) in a contemporary neonatal/pediatric (1/4-inch) and adolescent/adult (3/8-inch) extra-corporeal membrane oxygenation (ECMO) circuit including the..

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Blood Products, Crystalloids, and Rapid Infusion: An Experimental Study With Magnesium

Abstract Objectives Calcium and magnesium are concentration-dependent pro- and anticoagulant cofactors, and magnesium behaves similarly to calcium in the presence of citrate. The authors hypothesized that magnesium can cause clot..

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Beneficial effect of ECMO on survival in patients affected by ARDS due to COVID-19.

Abstract Where is the imperceptible difference? With great interest, we read the recent article by Whebell and colleagues [1] and were appealed by the beneficial effect of extracorporeal membrane oxygenation..

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Monitoring of Cerebral Oxygen Saturation in Interhospital Transport of Patients Receiving Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) in acute respiratory distress syndrome (ARDS) is used to achieve oxygenation and protect lung ventilation. Near infrared spectroscopy (NIRS) measures cerebral regional tissue oxygenation (rSO2)..

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The effect of a structured ECPR protocol aided by specific simulation training in a quaternary ECMO centre: A retrospective pre-post…

Abstract Background There is limited literature exploring the relationship between simulation training and  cardiopulmonary resuscitation (ECPR) outcomes. We examined whether there was an association between the implementation of an  training program and..

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Assessment of cardiac recovery in patients supported with venoarterial extracorporeal membrane oxygenation

Abstract Aims Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly being used to support patients in cardiogenic shock (CS). Early determination of disposition is paramount, as longer durations of support have..

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Outcomes by cannulation methods for venovenous extracorporeal membrane oxygenation during COVID-19: A multicenter retrospective study

Abstract Purpose To determine if a cannulation method for venovenous extracorporeal membrane oxygenation (V-V ECMO) is related to patient outcome. Methods A retrospective, multicenter study of adult patients (≥18 years old)..

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Incidence of Venous Thromboembolism in Adults Receiving Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) has become an increasingly used tool for cardiorespiratory support. Thrombosis is a well-recognized complication of ECMO, yet the burden of disease remains unclear. We undertook..

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