Cannulation

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Principles and Functions of Cardiopulmonary Bypass (CPB).

Cardiopulmonary Bypass (CPB) is one of the most critical advancements in cardiac surgery. It allows the surgical team to operate on a non-beating heart by temporarily taking over the functions..

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Pioneering MiECC in Pakistan: First Experience at Punjab Institute of…

Introduction Cardiopulmonary bypass (CPB) has long been a cornerstone of cardiac surgery. However, conventional CPB circuits are associated with a range of physiological disturbances including hemodilution, inflammatory response, and coagulopathy...

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The Interplay Between and Among Various Participants Within the Cardiac…

Introduction Cardiac surgery is a highly specialized and complex field that requires the seamless coordination of multiple professionals, each bringing their expertise to ensure a successful outcome. The success of..

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Theoretical Foundations of Cardiopulmonary Bypass: Bridging Science, Engineering, and Clinical…

Introduction: A Heart That Pauses, A Circuit That Lives When the heart is arrested during cardiac surgery, life continues—thanks to cardiopulmonary bypass (CPB). The theoretical underpinnings of CPB stem from..

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The Ethical, Professional, and Legal Implications of Perfusion Practice: A…

Abstract Perfusionists are central to life-sustaining interventions such as cardiopulmonary bypass (CPB), extracorporeal membrane oxygenation (ECMO), and mechanical circulatory support. While the technical dimensions of their work are well recognized,..

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Guidelines for the Use of 100% Oxygen on Ventilator and…

Introduction Oxygen is vital to life and a central element of cardiopulmonary support. During cardiac surgery—whether on mechanical ventilation or cardiopulmonary bypass (CPB)—100% oxygen is often used out of tradition..

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Case Report: Oxygenator Burst During Minimally Invasive Coronary Artery Bypass…

Abstract This case report discusses a rare and critical perfusion accident during a minimally invasive coronary artery bypass grafting (CAGB) procedure, where a Eurosets Skipper oxygenator burst 3 minutes after..

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The Clinical Relevance of Carbon Dioxide Management During Cardiopulmonary Bypass…

Abstract Background: Management of arterial carbon dioxide tension (PaCO₂) during extracorporeal circulation is critical to maintaining physiological stability. Both cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) significantly alter natural..

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Management of Patients with Renal Failure on Cardiopulmonary Bypass

Abstract Renal failure presents a significant challenge in patients undergoing cardiopulmonary bypass (CPB), as they are at high risk for acute kidney injury (AKI), electrolyte imbalances, and fluid overload. The..

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Inflammatory Response and Inflammatory Mediators in Cardiopulmonary Bypass: Management Strategies

Introduction Cardiopulmonary bypass (CPB) is a life-saving technology used in cardiac surgery; however, it triggers a systemic inflammatory response (SIRS) due to blood contact with non-endothelial surfaces, ischemia-reperfusion injury, and..

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