Yearly Archives: 2026

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A Plan-Do-Study-Act Cycle to Enhance Operational Efficiency in a Newly Established Paediatric Cardiac Operating Room

Abstract Objectives This quality improvement project aimed to enhance operating room efficiency in a newly established paediatric cardiac operating room by focusing on key performance indicators (KPI), including (1) first..

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Perioperative Transfusion Requirements in Pediatric Patients Receiving Apixaban Prior to Cardiac Surgery With Cardiopulmonary Bypass

Abstract Design Apixaban is a direct oral anticoagulant that inhibits factor Xa. Our objective was to examine the effect of apixaban on perioperative transfusion requirements in pediatric patients undergoing cardiac..

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Hemodynamic monitoring strategies in cardiac surgery: an update systematic review

Abstract Hemodynamic monitoring is a cornerstone of perioperative care in cardiac surgery, where patients are at high risk of cardiovascular instability and organ hypoperfusion. In recent years, goal-directed therapy (GDT)..

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Is Cooler Safer and More Advantageous? A Feasibility Study in Rabbits

Abstract Objectives This study hypothesizes that induced hypothermia (IH) can safely extend aortic cross-clamp (ACC) time, significantly reducing metabolic burden and end-organ injury, thereby enabling more comprehensive aortic arch reconstructions..

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Increased Incidence of Thrombosis in Patients at Risk of Heparin-Induced Thrombocytopenia Receiving Epoprostenol for Cardiac Surgery

Abstract Objective Heparin-induced thrombocytopenia (HIT) is a serious concern in cardiac surgery, as heparin use in the at-risk patient can lead to devastating thrombosis. Management strategies for patients with confirmed..

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Safety and Efficacy of Stored Wet-Preprimed Extracorporeal Membrane Oxygenation Circuits: A Scoping Review

Abstract Extracorporeal membrane oxygenation (ECMO) may be a life-saving intervention for patients with respiratory or cardiac failure or cardiac arrest. Storing wet-preprimed ECMO circuits can reduce the time to initiate..

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The history of cardiopulmonary bypass and the evolution of pneuma in cardiopulmonary medicine

Abstract Cardiopulmonary bypass (CPB) is one of the most groundbreaking medical innovations in history, enabling safe and effective heart surgery by temporarily replacing the function of the heart and lungs...

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Polymeric micro and nanoparticle release from cardiopulmonary bypass and extracorporeal membrane oxygenation circuits

Abstract Objectives Cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) or life support (ECLS) circuits are built from polymers and might release polymeric micro- and nanoparticles (MNP) into the circulation...

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Tissue perfusion pressure: A novel hemodynamic measure to assess risk of acute kidney injury after cardiac surgery

Abstract Background Optimal hemodynamic targets for preventing acute kidney injury (AKI) have remained elusive. We hypothesized that lower tissue perfusion pressure (TPP), a novel perfusion index representing the difference between..

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Detection of Thrombi in Extracorporeal Membrane Oxygenation Circuits Using Low-Frequency Acoustic Measurements

Abstract Extracorporeal membrane oxygenation (ECMO) provides temporary support for patients with severe acute cardiac or respiratory failure. Although thrombotic complications are common during ECMO, the real-time detection and management of..

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Getinge Webinar: Basics of neonatal and pediatric ventilation

Overview Title: Getinge Webinar: Basics of neonatal and pediatric ventilation Learning objectives: Understand the ventilation principles of neonatal and pediatric ventilation. Identify various modes of ventilation used in neonatal and pediatric..

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The case against infusing ABO incompatible antibody and antigen from all blood components

Abstract The transfusion of ABO compatible but not ABO identical red blood cells and plasma and the transfusion of platelets and cryoprecipitate without concern for ABO in any manner, are..

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Labeled surgical caps improve perioperative patient safety and interprofessional communication in the operating room: a scoping review

Abstract Background Effective communication is critical for patient safety and surgical outcomes inside the operating room (OR). Labeled surgical caps have been proposed as a strategy to improve intraoperative communication..

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Extracorporeal membrane oxygenation escape room simulation teamwork dynamics and effectiveness

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a high-risk, low-frequency intervention requiring specialized training and effective teamwork, for which simulation-based training is a valuable tool. Across medical disciplines escape room-style..

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Acute pulmonary hypertension induced by heparin–protamine complex during thoracoabdominal aortic grafting

Abstract Background Protamine has a more difficult side-effect profile. Circulatory collapse has been reported as a result of acute pulmonary artery spasm caused by complement cascade activation by large heparin–protamine..

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Can a low prime volume arterial filter be used as an alternative for a venous bubble trap in minimal extracorporeal…

Abstract Background During cardiac surgery the use of a minimal extracorporeal circulation (MiECC) system may reduce the adverse effects for the patient. This is probably caused by reduced inflammation and..

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Glycocalyx Degradation in Pediatric Patients with Cyanotic and Acyanotic Congenital Heart Disease Undergoing Cardiac Repair Surgery

Abstract Background/Objectives: In the present study, we hypothesized that cardiac surgery in pediatric patients with congenital heart disease (CHD) leads to profound endothelial glycocalyx degradation, measured as the increase in..

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Carbon Dioxide Elimination With Flow-Controlled Ventilation in Lung Transplantation: A Case Report

Abstract Background Lung transplantation represents the most definitive treatment option for patients with advanced-stage lung diseases. In recent years, improvements in anesthetic techniques, medical technologies, and coordinated perioperative care have..

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Advanced bilateral EEG monitoring for neuroprotection in high-risk cardiac surgery: a successful case report of emergency ascending aortic replacement

Abstract Background Aortic surgery involving circulatory arrest and unilateral cerebral perfusion may be associated with hemispheric differences in scalp-recorded electroencephalographic (EEG) activity that are not detected by standard intraoperative monitoring...

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Biomarkers for acute kidney injury: a pragmatic approach

Abstract Traditionally, the diagnosis of kidney disease has relied primarily on serum creatinine (SCr). For acute kidney injury (AKI), changes in urine output (UO) have also been recognized as a..

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Sex differences in venoarterial extracorporeal membrane oxygenation utilisation and clinical outcomes in Australia

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly utilised in critically ill patients with severe cardiac failure and cardiac arrest, yet sex-specific differences in presentation, utilisation, and clinical outcomes..

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Applied physiology at the bedside: using invasive blood pressure as a true monitoring tool

Abstract Invasive arterial blood pressure (BP) monitoring is a cornerstone of hemodynamic assessment in critically ill patients. This review explores how the individual components of BP—systolic arterial (SAP), diastolic arterial..

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Child Opportunity, Race, and Language in Congenital Cardiac Surgery Outcomes

Abstract Racial and ethnic disparities and language barriers coexist with inequities in a child’s educational, environmental, and economic opportunity. We evaluated the association between surgical outcomes and a composite child..

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Acute normovolaemic haemodilution after cardiac surgery: a meta-analysis of randomised controlled trials

Abstract Background Acute normovolaemic haemodilution (ANH) is a widely adopted packed red blood cells (pRBC) transfusion sparing strategy after cardiac surgery. While the intraoperative effect is plausible and likely enhanced..

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Beyond Concentration: Importance of Functional and Temporal Assessment of Fibrinogen After Cardiopulmonary Bypass

Abstract Terada et al. presented an important study on the dynamic relationship between plasma fibrinogen concentration and functional clot strength after cardiopulmonary bypass (CPB). Their findings underscore the multifactorial nature of..

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Comparison of 6% hydroxyethyl starch 130/0.4 vs 5% albumin in cardiopulmonary bypass for cardiac surgery

Abstract BACKGROUND The choice of priming and volume replacement fluids during cardiopulmonary bypass (CPB) in cardiac surgery impacts hemodynamic stability, coagulation, renal function, and patient outcomes. Hydroxyethyl starch (HES) 130/0.4..

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Advances in Extracorporeal Life Support: A Pediatric Perspective

Abstract The last 10 years have seen an exponential rise in the use of extracorporeal life support (ECLS), also frequently referred to as ECMO (extracorporeal membrane oxygenation) when a membrane..

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Highlights of the Nineteenth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion

Abstract The 19th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion took place on May 16 and 17, 2025, at the InRad Events Center of the..

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Anticoagulation Management of Patients with Antiphospholipid Syndrome Undergoing Cardiopulmonary Bypass in Cardiac Surgery: Challenges and Current Strategies

Abstract The antiphospholipid syndrome (APS) is a complex autoimmune disease that causes a state of hypercoagulability that can result in recurrent venous and arterial thromboses. APS may lead to cardiac..

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Association between autologous blood transfusion and serum creatinine in patients with acute Stanford-A aortic dissection based on a retrospective study

Abstract Background Autologous blood transfusion (ABT), as a blood conservation strategy, is widely used in surgeries for acute Stanford-A aortic dissection(ATAAD). However, investigations into the correlation between ABT and postoperative..

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