Monthly Archives: enero 2026

Perfusfind S.L.

Abstract Objective This study assessed the impact of intraoperative goal-directed fluid therapy integrated within an Enhanced Recovery After Surgery program on early coagulation parameters, transfusion requirements, hemoglobin levels, chest tube..

Perfusfind S.L.

Abstract Delaying the measurement of a complete blood count (CBC) for 6 to 24 hours after red blood cell transfusion remains a common practice in hospitals worldwide, despite the absence..

Perfusfind S.L.

Abstract Hereditary spherocytosis (HS) is a rare inherited haemolytic anaemia. This case report outlines a neonatal patient with presumed HS requiring cardiopulmonary bypass (CPB) and the whole blood exchange transfusion..

Perfusfind S.L.

Abstract Endothelin-1 is a potent regulator of vasomotor tone and promotes endothelium-dependent vasoconstriction of vascular smooth muscle. Dysregulated vasomotor tone is a hallmark of microvascular pathology following cardiac surgery involving..

Perfusfind S.L.

Abstract BACKGROUND: The aim of this study was to present our institutional experience with periprocedural management of emergency cesarean section (CS) operations and maternal and fetal cardiac complications in pregnant..

Perfusfind S.L.

Abstract Background and objective Cardiopulmonary bypass (CPB), though indispensable in cardiac surgery, carries significant risks of systemic embolization and organ injury. While cerebral and cardiac complications have been thoroughly investigated,..

Perfusfind S.L.

Abstract Introduction Post-CPB bleeding remains a critical challenge in neonatal cardiac surgery, and early detection of coagulopathy to guide transfusion decisions may offer significant benefits. We hypothesized that routine use..

Perfusfind S.L.

Abstract Introduction Monitoring indexed oxygen delivery (DO2i) is recommended during cardiopulmonary bypass (CPB) and a predictor of acute kidney injury (AKI). The use of lean body mass-adjusted blood flow rates..

Perfusfind S.L.

Abstract Excessive right heart load imposes an acute or chronic injury on the right ventricle (RV), predisposing critically ill neonates and cardiac surgical patients to RV failure, low cardiac output..

Perfusfind S.L.

Abstract Background: Postoperative delirium is a common and serious complication in surgical patients, often leading to prolonged hospitalisation and increased morbidity. Intranasal insulin has shown promising results in preventing postoperative..

Perfusfind S.L.

Abstract Introduction Temporary mechanical circulatory support (tMCS) has become essential in managing severe cardiac dysfunction, particularly refractory cardiogenic shock (CS). Despite widespread adoption, the optimal use of tMCS is often..

Perfusfind S.L.

Abstract Neuron-specific enolase (NSE) is a marker used to assess neurological impairment. Notwithstanding, the release of NSE into the circulation can also originate from erythrocytes and thrombocytes, signifying that even..

Perfusfind S.L.

Abstract Background The predominant method for preventing cerebral infarction secondary to air embolism in cardiac surgery is the use of root vents to remove air. However, in the case of..

Perfusfind S.L.

Abstract Objectives:  To test the feasibility and safety of a randomized controlled trial (RCT) delivering nitric oxide into the sweep gas of extracorporeal membrane oxygenation (ECMO) circuits (sNO) in critically..

Perfusfind S.L.

Abstract Background Postoperative complications in patients with acute type A aortic dissection (ATAAD) significantly affect their prognosis. This study investigates the association between cardiopulmonary bypass(CPB) weaning time and postoperative adverse..

Perfusfind S.L.

Abstract Introduction Significant blood loss (≥ 500 mL) during spinal surgery is common and linked to greater transfusion requirements and worse outcomes. Preoperative tools for risk stratification and individualized blood-management strategies..

Perfusfind S.L.

Abstract Background The purpose of this descriptive study was to characterize the utilization and outcomes of CPB after trauma. Methods This is an AAST-sponsored retrospective (2011-2021) multicenter (32 centers) study..

Perfusfind S.L.

Abstract Accurate, continuous assessment of regional tissue perfusion remains a significant clinical challenge, as most existing modalities are invasive, indirect, or impractical for routine monitoring. Near-infrared spectroscopy (NIRS) has been..

Perfusfind S.L.

Abstract Porcine livers have the potential to support liver function via extracorporeal liver cross-circulation (ELC) until recovery or transplantation. To assess the functional integrity of both native human and porcine..

Perfusfind S.L.

Abstract Background: The prognostic value of preoperative hemoglobin A1c (HbA1c) in patients undergoing cardiac surgery remains uncertain. This study investigated the association between preoperative HbA1c levels and the risk of..

Perfusfind S.L.

Abstract Objectives To evaluate the feasibility, safety, and early outcomes of a standardized operating room extubation (ORE) protocol implemented for elective cardiac surgery patients requiring cardiopulmonary bypass. Design A prospective..

Perfusfind S.L.

Abstract Background/Objectives: Cardiopulmonary bypass (CPB) facilitates complex cardiac surgery but can damage erythrocyte membranes, impairing microcirculation and oxygen transport. Standard rheological tests assess overall blood properties but fail to define..

Perfusfind S.L.

Abstract Objectives To monitor temporal changes in total and unbound remimazolam concentrations during cardiac surgery requiring cardiopulmonary bypass (CPB). Design Single-center, prospective, observational study. Setting Operating rooms of a university..

Perfusfind S.L.

Abstract Hemostasis depends on the coordinated interaction between platelets, coagulation factors, endothelium, and shear forces. Current point-of-care (POC) assays evaluate isolated components of haemostasis or operate under nearly static conditions,..

Perfusfind S.L.

Abstract ‘Liquid-like’ solid surfaces that overcome the limitations of lubricant-infused slippery surfaces, have garnered attention as passive antibiofouling coatings for biomedical applications. However, lack of intrinsic bioactivity limits its ability to..

Perfusfind S.L.

Abstract Due to the similar size ratios, adult porcine models are suitable for cardiovascular and circulatory physiology studies on extracorporeal circulation. As standard, the connection to the cardiopulmonary bypass (CBP)..

Perfusfind S.L.

Abstract In patients with or at risk of acute circulatory failure, capillary refill time (CRT) has emerged as a prognostic indicator, with data linking prolonged CRT to mortality and adverse..

Perfusfind S.L.

Abstract Antithrombin (AT), a glycoprotein, plays a key role in anticoagulation by inhibiting coagulation proteases. It is also the primary mediator of heparin's anticoagulant effect, with heparin binding amplifying AT..

Perfusfind S.L.

Abstract Background This study aimed to investigate the predictive value of the red cell distribution width-to-platelet ratio (RPR) for cardiac surgery-associated acute kidney injury (CSA-AKI). Methods A retrospective analysis of..

Perfusfind S.L.

Abstract Background: The Prognostic Nutritional Index (PNI) is a tool that combines serum albumin levels and lymphocyte count to assess a patient's nutritional and immune status. Malnutrition, often undetected in coronary..