Perfusfind S.L.
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Perfusion Strategy to Prevent Right Ventricular Decompression on Cardiopulmonary Bypass During Extracardiac Fontan for Right Ventricle–Dependent Coronary Circulation

Abstract Early and long-term outcomes in patients with pulmonary atresia-intact ventricular septum undergoing staged univentricular palliations have been known to be adversely affected by the presence of right ventricle–dependent coronary..

Lee mas
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The need for a structured pathway to facilitate perfusionist mobility across borders

Abstract This letter highlights the need for a structured pathway for Perfusionists to work across borders in order to address workforce shortages and provide comparable opportunities to other medical professions...

Lee mas
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Temperature analysis of aortic repair with hypothermic circulatory arrest to quantify the injury by cooling

Abstract OBJECTIVES We analyzed the temperature in proximal aortic repair with moderate hypothermic circulatory arrest (HCA) and evaluated the effect of the cooling status on postoperative outcomes. METHODS A total..

Lee mas
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Integral assessment of gas exchange during veno-arterial ECMO: accuracy and precision of a modified Fick principle in a porcine model

Abstract Assessment of native cardiac output during extracorporeal circulation is challenging. We assessed a modified Fick principle under conditions such as dead space and shunt in 13 anesthetized swine undergoing..

Lee mas
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The next generation of evidence-based medicine

Abstract Recently, advances in wearable technologies, data science and machine learning have begun to transform evidence-based medicine, offering a tantalizing glimpse into a future of next-generation ‘deep’ medicine. Despite stunning..

Lee mas
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Albumin Infusion Reduces Fluid Loading for Postresuscitation Syndrome in a Pig Model of Refractory Cardiac Arrest Resuscitated With Venoarterial Extra…

Abstract Hemodynamic instability in postresuscitation syndrome worsens survival and neurological outcomes. Venoarterial extracorporeal membrane oxygenation (VA ECMO) for refractory cardiac arrest might improve outcomes. Hemodynamical support under VA ECMO relies..

Lee mas
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Perioperative cerebral perfusion in aortic arch surgery: a potential link with neurological outcome

Abstract OBJECTIVES The aim of this study was to examine whether perioperative changes in cerebral blood flow (CBF) relate to postoperative neurological deficits in patients undergoing aortic arch surgery involving..

Lee mas
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Protamine dose to neutralize heparin at the completion of cardiopulmonary bypass can be reduced significantly without affecting post-operative bleeding

Abstract Background: Systemic anticoagulation with heparin during cardiopulmonary bypass (CPB) should be neutralized by protamine administration to restore normal hemostasis. Our previous study showed the protamine-to-heparin ratio (P-to-H) of 1:1..

Lee mas
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Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury

Abstract Background: Acute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass..

Lee mas
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Custodiol versus blood cardioplegia in pediatric cardiac surgery: a randomized controlled trial

Abstract Background Blood-based cardioplegia is the standard myocardial protection strategy in pediatric cardiac surgery. Custadiol (histidine-tryptophan-ketoglutarate), an alternative, may have some advantages but is potentially less effective at myocardial protection...

Lee mas
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Unveiling the Clinical Benefits of High-Volume Hemodiafiltration: Optimizing the Removal of Medium-Weight Uremic Toxins and Beyond

Abstract Dialysis treatment has improved the survival of patients with kidney failure. However, the hospitalization and mortality rates remain alarmingly high, primarily due to incomplete uremic toxin elimination. High-volume hemodiafiltration..

Lee mas
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Concomitant Use of VA-ECMO and Impella Support for Cardiogenic Shock

Abstract Background: VA-ECMO with concomitant Impella support (ECpella) is an emerging treatment modality for cardiogenic shock (CS). Survival outcomes by CS etiology with ECpella support have not been well-described. Methods: This study..

Lee mas
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The Effect of Visits by Operating Room Nurses Before Cardiac Surgery on Anxiety and Pain Management

Abstract Purpose Further studies are needed in line with the Enhanced Recovery for Cardiac Surgery (ERCS) protocols with a view to reducing anxiety and opioid use in cardiac surgery patients...

Lee mas
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Predictors of Survival Outcomes and Discharge Location following VA-ECMO

Abstract Background: Mortality and complication rates remain high with VA-ECMO. Understanding risk factors for mortality and post-ECMO functional status may aid conversations about prognosis. Methods: ELSO Registry data for adults supported with..

Lee mas
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An emerging complementary strategy to treat acute heart failure (AHF) and cardiogenic shock (CS): the first clinical trial in China…

Abstract Mechanical circulatory support (MCS) is an emerging therapy for acute heart failure (AHF) or cardiogenic shock (CS) patients unresponsive to medicinal treatment. In China, common treatments using short-term MCS..

Lee mas
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Early Left Ventricular Unloading or Conventional Approach After Venoarterial Extracorporeal Membrane Oxygenation: The EARLY-UNLOAD Randomized Clinical Trial

Abstract BACKGROUND: Although venoarterial extracorporeal membrane oxygenation (VA-ECMO) is beneficial for the treatment of profound cardiogenic shock, peripheral VA-ECMO cannulation can increase left ventricular afterload, thus compromising myocardial recovery. We..

Lee mas
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3D-Printed silicone anatomic patient simulator to enhance training on cardiopulmonary bypass

Abstract Background: Simulator training is important for teaching perfusion students fundamental skills associated with CBP before they start working in the clinic. Currently available high-fidelity simulators lack anatomic features that..

Lee mas
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The role of ECMO support in airway procedures

Abstract The role of ECMO support in airway procedures

Lee mas
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Plasma-Free Strategy for Cardiac Surgery with Cardiopulmonary Bypass in Infants < 10 kg: A Retrospective, Propensity-Matched Study

Abstract Background: Infants < 10 kg undergoing cardiac surgery with cardiopulmonary bypass (CPB) may receive either fresh frozen plasma (FFP) or other solutions in the CPB priming volume. The existing..

Lee mas
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Porcine Normothermic Isolated Liver Perfusion

Abstract Porcine models of liver ex situ normothermic machine perfusion (NMP) are increasingly being used in transplant research. Contrary to rodents, porcine livers are anatomically and physiologically close to humans, with similar..

Lee mas
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Advanced hemocompatible polyethersulfone composite artificial lung membrane with efficient CO2/O2 exchange channel constructed by modified carbon nanotubes network

Abstract Artificial lung membranes as the core module of the extracorporeal membrane oxygenation technology (ECMO) execute the function of extracorporeal blood-gas barrier accomplishing CO2/O2 exchange with blood. However, the unsatisfactory hemocompatibility..

Lee mas
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Efficacy and safety of inhaled nitric oxide administered during cardiopulmonary bypass for pediatric cardiac surgery: a systematic review and meta-analysis

Abstract Background and aims:  Cardiopulmonary bypass (CPB) utilized for cardiac surgeries has been associated with significant mortality and adverse outcomes. The benefits of incorporating nitric oxide (NO) into the CPB..

Lee mas
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The Prognostic Value of Johns Hopkins Hospital Nutrition Support Score in Older Patients Undergoing Cardiovascular Surgery

Abstract Objectives Clarify the prognostic value of the Johns Hopkins Hospital Nutrition Support (JHHNS) score on clinical outcomes in older patients undergoing  with  (CPB). Design A retrospective observational study. Setting A teaching..

Lee mas
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Evaluation of the endotracheal tube cuff pressure changes during cardiac operations under cardiopulmonary bypass

Abstract Introduction: Tracheal intubation is used for most operations under general anesthesia. Prolonged hyperinflation of the tube cuff can compromise tracheal mucosal perfusion, and low pressure of the cuff may cause..

Lee mas
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Expert consensus on training and accreditation for extracorporeal cardiopulmonary resuscitation an international, multidisciplinary modified Delphi Study

Abstract Background A multidisciplinary group of stakeholders were used to identify: (1) the core competencies of a training program required to perform in-hospital  initiation (2) additional competencies required to perform pre-hospital  initiation..

Lee mas
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Outcomes of Extracorporeal Life Support Utilization for Pediatric Patients With COVID-19 Infections

Abstract Outcomes of pediatric patients who received extracorporeal life support (ECLS) for COVID-19 remain poorly described. The aim of this multi-institutional retrospective observational study was to evaluate these outcomes and..

Lee mas
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Association Between Thrombin–Antithrombin Complex and Acute Kidney Injury After Pediatric Cardiopulmonary Bypass Surgery: A Single-Center Retrospective Observational Study

Abstract Vascular endothelial damage may activate hypercoagulation and contribute to the development of acute kidney injury (AKI). This study aimed to investigate whether early alteration in coagulation was associated with..

Lee mas
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‘Herding cats’: A mixed methods investigation into the educational value of debriefing in operating theatres

Abstract Aim: The aim of the study was to explore the value of debriefing to enhance learning within operating theatres. Methods: A sequential mixed method study was undertaken at a..

Lee mas
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Clinical efficacy of intraoperative Cell Saver autologous blood salvage in emergency surgery for massive hemothorax

Abstract The objective of this study was to investigate the efficacy of intraoperative Cell Saver blood salvage during emergency surgery for massive hemothorax on minimizing perioperative allogeneic red blood cell..

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