Perfusfind S.L.

Abstract Artificial intelligence (AI), predictive analytics, and digital health technologies are progressively reshaping extracorporeal circulation and perioperative cardiovascular care. In this evolving landscape, cardiopulmonary bypass management is transitioning from a..

Perfusfind S.L.

Abstract Recirculation reduces the efficiency of venovenous extracorporeal membrane oxygenation (V-V ECMO), but patient-specific determinants of recirculation and the feasibility of recirculation-guided flow adjustment are not well defined. In this..

Perfusfind S.L.

Abstract Unfractionated heparin (UFH) has long been an anticoagulant of choice. Despite the increasing use of low molecular weight heparin derivatives and more recently direct oral anticoagulants, UFH is still..

Perfusfind S.L.

Abstract In children, validated tools to monitor anaesthetic depth are lacking. In routine practice, dosing of volatile agents relies on surrogate markers such as minimum alveolar concentration and autonomic responses. In..

Perfusfind S.L.

Abstract Background Frozen plasma (FP) is the standard haemostatic therapy after cardiopulmonary bypass, but recent trials indicate that FP is inferior to four-factor prothrombin complex concentrate (PCC). Citrate content may..

Perfusfind S.L.

Abstract Multimodal neurologic prognostication (MM-NP) after cardiac arrest has been shown to enhance prognostic accuracy, however, it is vastly underutilized in real-world settings. Guideline-discordant practices and healthcare disparities in post-cardiac..

Perfusfind S.L.

Abstract Objectives Coronary artery bypass grafting shows impaired outcomes in women compared to men. Investigation of sex-related outcome differences mostly comprises different operative strategies, potentially hampering interpretation of data. We..

Perfusfind S.L.

Abstract Background Neonates with enterovirus myocarditis may require extracorporeal membrane oxygenation (ECMO). The contemporary prognosis and risk factors for mortality of neonates with enterovirus myocarditis supported on ECMO is unknown...

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) induces inflammation partly via leukocyte activation. We conducted a first-in-human pilot study assessing the feasibility and perioperative safety of a novel activated leukocyte adsorption device during..

Perfusfind S.L.

Abstract Background Primary graft dysfunction (PGD) remains the leading cause of early morbidity and mortality after heart transplantation. Despite consensus definitions, clinicians still rely on subjective, indirect assessments of graft..

Perfusfind S.L.

Abstract Background Pediatric patients undergoing cardiac surgery are at risk for developing positive cumulative fluid balance (CFB). Our goal was to study postoperative CFB in this population, its explanatory variables,..

Perfusfind S.L.

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for providing adequate organ support in cardiogenic shock. While the intervention provides circulatory and respiratory support in the critical stage, it..

Perfusfind S.L.

Abstract Objective Severe anaphylaxis is a rare but life-threatening condition that may require extracorporeal life support (ECLS). A systematic review was conducted to evaluate the outcomes of patients receiving ECLS..

Perfusfind S.L.

Abstract Objectives Core temperature is routinely used to guide hypothermic circulatory arrest (HCA) for acute type A aortic dissection (ATAAD). However, it remains unclear whether impaired carotid artery flow alters..

Perfusfind S.L.

Abstract BACKGROUND: Acute normovolemic hemodilution (ANH) is endorsed by contemporary patient blood management guidelines as a cost-effective strategy for reducing allogeneic transfusion in cardiac surgery. However, evidence remains inconsistent due..

Perfusfind S.L.

Abstract Background This study aimed to evaluate in-hospital mortality and to identify predictors of mortality in coronary artery bypass grafting (CABG) patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. Methods..

Perfusfind S.L.

Abstract Background Use of extracorporeal membrane oxygenation (ECMO) for cardiorespiratory failure has increased substantially. While long-term outcomes for psychological health are increasingly assessed and addressed in critical care survivorship research,..

Perfusfind S.L.

Abstract Background: The clinical benefits of pulsatile perfusion during cardiopulmonary bypass (CPB) remain a subject of debate. This study aimed to compare clinical outcomes between pulsatile and non-pulsatile perfusion during..

Perfusfind S.L.

Abstract Objectives To determine whether individualized heparin dosing guided by a heparin dose-response (HDR) curve is noninferior to conventional weight-based dosing in achieving target activated clotting time (ACT) of ≥480..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical life-support intervention for patients with severe respiratory and circulatory failure. Nevertheless, identifying the optimal timing of ECMO initiation and its correlation..

Perfusfind S.L.

Abstract The expanding use of extracorporeal cardiopulmonary resuscitation (ECPR) has introduced new clinical scenarios at the intersection of extracorporeal life support and organ donation. Current donor classification systems do not..

Perfusfind S.L.

Abstract Background: Simulation-based education (SBE) is increasingly used in training students in allied healthcare, yet data on its role in United States (U.S.) perfusion programs are limited. This study surveyed perfusion..

Perfusfind S.L.

Abstract Background Human factors (HF) are integral to patient safety. Simulation-based education (SBE) is widely used to teach HF, yet facilitators conceptualise HF in varied ways. This study explored facilitators’..

Perfusfind S.L.

Abstract Simulation is an excellent educational methodology for healthcare learners to practice skills for medical scenarios that are low in frequency but high in emotional intensity. However, these educational experiences..

Perfusfind S.L.

Abstract Background: Hemodilution during cardiopulmonary bypass (CPB) is a standard perfusion strategy used to reduce blood viscosity and enhance microcirculatory flow. The hemodilution rate, expressed as hemoglobin (Hb) concentration, is..

Perfusfind S.L.

Abstract This study describes the development and preliminary validation of an integrated clinical decision support application (Cardiac Critical Care Advisor Pro, CCA Pro v6.0) that combines viscoelastic coagulation analysis, arterial..

Perfusfind S.L.

Abstract Background Extracorporeal Cardiopulmonary Resuscitation (ECPR) is increasingly considered for prehospital cardiac arrest management; however, its impact on resuscitation performance remains unclear. This study aimed to determine whether integrating an..

Perfusfind S.L.

Abstract Background Children undergoing high-risk cardiac surgery face significant postoperative morbidity and mortality risk, and early recognition of impaired systemic perfusion is critical. Current monitoring modalities, such as lactate, central..

Perfusfind S.L.

Abstract Platelets play a pivotal role in hemostasis, where their activation is tightly regulated by biochemical agonists such as thrombin, collagen, and adenosine diphosphate, all of which signal through calcium-mediated..

Perfusfind S.L.

Abstract Background The clinical impact of early spontaneous breathing during veno-venous extracorporeal membrane oxygenation (VV ECMO) for acute respiratory distress syndrome (ARDS) is unclear, balancing potential benefits (reducing sedation and..