Perfusfind S.L.
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Reliable Flow, Cost-Effective, Comfortable: Tunneled Veno-Pulmonary Artery Extracorporeal Membrane Oxygenation Cannulation Technique

Abstract Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) has many limitations, including patient comfort and, oftentimes, mobility issues. Veno-pulmonary (VP) ECMO offers respiratory support without recirculation and right heart support. For..

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Coronary slow flow: role of systemic inflammation and biomarkers in its pathophysiology

Abstract Background Coronary slow flow (CSF) is characterized by reduced coronary blood flow velocity in the absence of significant obstruction, and it has been associated with systemic inflammation and endothelial..

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Cardiopulmonary bypass time, intraoperative hematocrit and transfusion predict neurocognitive decline in patients undergoing cardiac surgery

Abstract Background Neurocognitive decline (NCD) after cardiopulmonary bypass is a well-established phenomenon. While numerous preoperative risk factors have been identified, the influence of intraoperative factors on NCD still needs further..

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Venovenous Extracorporeal Membrane Support in the Setting of Type A Aortic Dissection Repair—Too Little Too Late?

Abstract Background Use of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) in the setting of type A aortic dissection (TAAD) has been described in the literature as salvage therapy, with morbid..

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The effects of mechanical ventilation during v-a ecmo support: a systematic review

Abstract Background Mechanical ventilation is routinely used during veno-arterial extracorporeal membrane oxygenation (V-A ECMO), but its role in influencing hemodynamics and supporting cardiac recovery remains poorly understood. This systematic review..

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Evaluation of a Novel Intelligent Interruption Management System in High-Fidelity Simulated Cardiac OR to Improve Surgical Safety

Abstract Surgical flow disruptions during complex cardiac surgery procedures may cause preventable errors and patient harm. Prior work has shown that timing interruptions during moments of lower cognitive workload (CogL)..

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Novel Extracorporeal Life Support System to Mitigate Ischemia-Reperfusion Injury During Prolonged Aortic and Inferior Vena Caval Occlusion

Abstract Extracorporeal membrane oxygenation (ECMO) and endovascular balloon occlusion of the aorta (REBOA) have been reported to manage hemodynamics and reduce blood loss and transfusion requirements during high-risk abdominal surgeries...

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The effect of intravenous calcium administration on haemodynamics in perioperative cardiothoracic surgery and intensive care: A narrative review

Abstract Calcium plays an essential role in myocardial contractility, excitation-contraction coupling, and vascular tone. In cardiothoracic surgery, calcium supplementation is frequently administered during weaning from cardiopulmonary bypass (CPB) and in..

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Outcomes after extracorporeal membrane oxygenation following the norwood procedure: a systematic review and meta-analysis

Abstract Background Survival following the Norwood procedure has improved substantially, but outcomes for the high-risk subgroup requiring postoperative extracorporeal membrane oxygenation (ECMO) remain unclear. We explored short- and intermediate-term outcomes..

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Blood Lactate Clearance as a Predictor of Mortality in Children Undergoing Cardiac Surgery with Cardiopulmonary Bypass

Abstract Background: Pediatric cardiac surgery is still a high-risk procedure, with mortality being a significant concern. Lactate clearance has been demonstrated to enhance outcomes in critically ill adult populations; however, data..

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Characteristics and outcomes of younger adults with out-of-hospital cardiac arrest resuscitated with extracorporeal membrane oxygenation: a nationwide study

Abstract Background Extracorporeal cardiopulmonary resuscitation has shown promise in out-of-hospital cardiac arrest, but evidence in younger adults remains limited. Younger adults represent a unique subgroup with distinct etiologies and potentially..

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Diagnostic Imaging Challenges During Extracorporeal Membrane Oxygenation

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical life support therapy for severe cardiac and respiratory failure, but it is associated with thromboembolic, hemorrhagic, and neurological complications. Diagnostic imaging..

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The Effect of ABO Blood Groups and Rhesus Factor on Cardiac Surgery Performed with Cardiopulmonary Bypass

Abstract In cardiac surgery operations with cardiopulmonary bypass (CPB), patients are connected to a heart-lung machine and the patient's blood comes into contact with nonphysiological extracorporeal circulation equipment. Aims: In..

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Renal pulsatility index assessment by intraoperative doppler ultrasound is associated with acute kidney injury after cardiac surgery: a prospective observational…

Abstract Background Acute kidney injury (AKI) is a common complication among patients undergoing cardiac surgery. Perioperative ultrasound assessment of renal hemodynamic parameters has emerged as a potential tool for predicting..

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Anticoagulation Strategies in Adults Undergoing Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for patients with severe cardiac or respiratory failure, but it is associated with a high risk of thrombotic and bleeding..

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A 27-Year Comparative Analysis of Off-Pump and On-Pump Coronary Artery Bypass Grafting in Octogenarians

Abstract Background Octogenarians are deemed a high-risk patient population with increased postoperative morbidity and mortality after conventional coronary artery bypass grafting with cardiopulmonary bypass. In such patients, reducing the invasiveness..

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Costs and complications of extracorporeal membrane oxygenation therapy in Australia and New Zealand

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving form of cardiopulmonary support for patients with severe refractory cardiopulmonary disease. It is a resource-intensive intervention requiring specialised equipment and personnel,..

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Evolution of Femoral Cannulation Techniques in Minimally Invasive Mitral Valve Surgery: A 10-Year Experience

Abstract Background: Femoral cannulation is essential for minimally invasive mitral valve surgery (MIMVS). Our center transitioned from open femoral cut-down to ultrasound-guided percutaneous cannulation supported by smart venous cannulas, ThruPort arterial..

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Procuring organs from a complex donor presenting with a double Azygos system

      Procuring organs from a complex donor presenting with a double Azygos system, anatomically corrected malposition of the great arteries (ACMGA), a hypoplastic left hemithorax, and severe kyphoscoliosis..

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A Cohort, Semi-Randomized, open label quality improvement patient blood management (PBM) comparison of point of care viscoelastic coagulation monitors in…

Abstract Viscoelastic testing (VET), recommended for heart surgery, lacks adoption due to data reporting times (central laboratory coagulation assay-CLCA and laboratory VET tests) and interpretation (predicate VET devices). Three point..

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Impaired Cerebral Autoregulation in Pediatric Patients with ECMO: A Retrospective Analysis of ECMO Time Periods and Association with Neurologic Injury

Abstract Objective Neurologic injury is common in pediatric patients with extracorporeal membrane oxygenation (ECMO). Impaired cerebral autoregulation (CAR) may increase the risk of neurologic injury. We aimed to measure CAR..

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Comparison of Left Ventricular Pressure-Volume Loops With Veno-Arterial Extracorporeal Membrane Oxygenator Support: In Vitro Investigation

Abstract Background The hemodynamic consequence of increasing veno-arterial extracorporeal membrane oxygenator (V-A ECMO) flow on left ventricular (LV) loading is controversial, with in vivo studies reporting conflicting results on left ventricular..

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Program of quality improvement for extracorporeal blood purification therapies in the intensive care unit

Abstract Critically ill patients often require complex extracorporeal treatments, such as extracorporeal blood purification (EBP). At the bedside, there can be reluctance or uncertainty about when to initiate EBP, and..

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Clinical Outcomes of Different Heparin Anticoagulation Monitoring Targets in Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis

Abstract Objectives This systematic review and meta-analysis aimed to evaluate clinical outcomes associated with different systemic heparin protocols (conservative v standard intensity) during extracorporeal membrane oxygenation (ECMO) support. Included studies comprised both..

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Feasibility of “Awake” Extracorporeal Membrane Oxygenation Cannulation Before Intubation in Children

Abstract When the risk of cardiopulmonary arrest during intubation is high, “awake” extracorporeal membrane oxygenation (ECMO) cannulation with sedation and a natural airway may provide hemodynamic stability and gas exchange..

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Safety and efficacy of OASSIST ECMO system: A first-in-human, multi-center, clinical trial

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) provides respiratory and circulatory support in patients with severe cardiorespiratory failure. As ECMO technology advances, portability has become an important design consideration for transport..

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Peripheral perfusion noninvasive monitoring technologies - a literature and patent review

Abstract Shock is a life-threatening condition marked by inadequate tissue perfusion and oxygen supply, leading to organ failure if not rapidly addressed. Clinical management of shock involves detecting and correcting..

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Feasibility of estimating cardiac indices using cardiac surgery anesthesia records in a multicenter cohort

Abstract Cardiac index (CI) is a key physiologic indicator correlated with end-organ perfusion in cardiac surgical patients, yet it is not routinely measured in all cases. This study evaluated the..

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Hypothermia exacerbates kidney injury during extracorporeal cardiopulmonary resuscitation

Abstract Objective Kidney injury is one of the most common complications of extracorporeal cardiopulmonary resuscitation (ECPR), yet the renoprotective effects of temperature management during ECPR remain inconclusive. This study aimed..

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Methemoglobin Formation Reflects Systemic Nitric Oxide Uptake: The Critical Role of Delivery Method—Results from Secondary Analysis of a Randomized Controlled…

Abstract Objectives Methemoglobin (metHb) is routinely monitored as a safety marker during inhaled nitric oxide (NO) therapy but may also reflect systemic NO uptake. This study aims to investigate how..

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