Abstract Atrial fibrillation (AF) is a highly prevalent arrhythmia and a major cause of morbidity and mortality. Although AF is not a primarily immunologic disorder, increasing clinical, translational, and experimental..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) cannulation during refractory cardiac arrest has become a key therapeutic option in contemporary critical care medicine. When initiated in a timely manner, extracorporeal cardiopulmonary resuscitation..
Read MoreAbstract Post–myocardial infarction (PMI) ventricular septal defect (VSD) repair is associated with high mortality., The pathophysiology varies based on the size of the infarction and the VSD, which results in..
Read MoreAbstract To optimize and evaluate the hydrodynamic performance and gas exchange efficiency of a newly developed centrifugal blood pump and membrane oxygenator for extracorporeal membrane oxygenation (ECMO) support, blood pump..
Read MoreAbstract Objective(s): Mean arterial pressure (MAP) after cardiac surgery may contribute to acute kidney injury (AKI). We sought to identify threshold MAP values during the first 24 hours (h) postoperatively..
Read MoreLearn ECMO, ECPR, and Bleeding Edge Resuscitation A sim lab, a procedure lab, and one-on-one teaching so you can initiate ECMO and perform the most advanced hemodynamic resuscitation on your..
Read MoreThis course is designed for learners who have completed the ELSO Virtual ECMO Training Course, ELSO Foundations: Adult ECMO Training Course, or for practitioners with a strong foundational knowledge of..
Read MoreAbstract Objectives Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly employed for patients with refractory cardiac arrest, yet optimal criteria for patient selection remain poorly understood. Pre-cannulation lactate and pH values are..
Read MoreAbstract Platelets play a fundamental role in hemostasis; however, their phenotype, reactivity, and function vary across the pediatric age spectrum. While developmental differences in plasma coagulation proteins have been well-characterized..
Read MoreAbstract The International Society on Thrombosis and Haemostasis (ISTH) recently published a survey on the management of unfractionated heparin (UFH), which revealed substantial heterogeneity in practice and highlighted the need..
Read MoreDr.Sam Zeraatian Nejad Davani, Cardiovascular and Thoracic Surgeon, Transplant and Thoracic Organs Recovery Surgeon. Director of Georgia Atlanta Procure on Demand Thoracic Organs Transplant and Procurement Surgery. ..
Read MoreIn Thoracoabdominal Normothermic Regional Perfusion (TA-NRP) for Donation after Circulatory Death (DCD), initiating central cannulation with a venous-first approach serves as a critical step to decompress an acutely..
Read MoreAbstract Aim Early downward temperature drift is a common event of pre-hospital extracorporeal cardiopulmonary resuscitation (e-CPR), since prehospital extracorporeal membrane oxygenation (VA-ECMO) circuits often lack heat-exchangers. However, whether this core..
Read MoreAbstract Background Despite advances in patient blood management, the optimal hemoglobin threshold for Red Blood Cell (RBC) transfusion remains controversial. This observational study evaluated the association between the relative decline..
Read MoreAbstract Aims Acute kidney injury (AKI) is common in patients treated with microaxial flow pumps (mAFP). Plasma-free haemoglobin (PFHb) due to haemolysis is known to increase kidney injury in a..
Read MoreAbstract Background: Cardiac‑surgery‑associated acute kidney injury (CSA‑AKI) is a frequent postoperative complication worldwide and is associated with increased mortality, prolonged intensive care unit stay, and substantial resource utilization. While reported..
Read MoreAbstract Background Hemolysis is a recognized complication of mechanical circulatory support and may contribute to acute kidney injury in patients with cardiogenic shock. Early hemolysis during Impella support, particularly compared..
Read MoreAbstract In managing ECMO, preventing thrombus formation and hemolysis is crucial. While centrifugal pumps are increasingly used in pediatric ECMO, pumps designed for low flow range are not approved in..
Read MoreAbstract Objectives Low haematocrit during cardiopulmonary bypass is a known risk factor for acute kidney injury, but it is unclear whether high haematocrit also increases acute kidney injury risk. We..
Read MoreAbstract Optimal oxygen target levels for critically ill patients have been discussed for decades and very low but also high PaO2-levels were both associated with higher mortality [, ]. In..
Read MoreAbstract Heparin-induced thrombocytopenia (HIT) represents a high-risk perioperative challenge in patients undergoing cardiac surgery. Although unfractionated heparin remains the standard anticoagulant for cardiopulmonary bypass (CPB), its use in patients with..
Read MoreLiquid Lung Rest During Extracorporeal Life Support in a Neonatal Porcine Model of Acute Lung Injury
Abstract In patients with severe lung injury, extracorporeal life support (ECLS) enables lung rest, but the optimal strategy is unknown. This study compared liquid lung rest (LLR) versus standard gas rest ventilation..
Read MoreAbstract Background: Among infants undergoing cardiac surgery, AKI may affect as many as 40% of this population and carries an unfavorable prognosis. A range of contributors has been implicated, including early..
Read MoreAbstract Fluid administration and fluid balance are both important clinical considerations in the management of patients receiving extracorporeal membrane oxygenation (ECMO). Insufficient intravascular volume may limit the output of preload-dependent..
Read MoreAbstract Background and Objectives: Endoscopic beating-heart tricuspid valve (TV) surgery is increasingly adopted in cardiac surgery due to its association with improved postoperative recovery. Conventional approaches require jugular vein cannulation..
Read MoreAbstract Introduction In patients with prior valve replacement requiring venoarterial extracorporeal membrane oxygenation (VA ECMO), there is a risk of prosthetic valve thrombosis (PVT) due to intracardiac stasis. We describe..
Read MoreAbstract Patients supported with peripheral femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently face the challenge of determining the optimal timing for weaning trials, as no universally standardized bedside method is..
Read MoreAbstract Early rehabilitation during venovenous extracorporeal membrane oxygenation used as a bridge to recovery (VV ECMO–BTR) may help preserve functional capacity. We retrospectively analyzed 153 adults supported with VV ECMO–BTR..
Read MoreAbstract Importance Two percent to 50% of patients undergoing elective cardiac surgery experience acute kidney injury (AKI) postoperatively. Medications to prevent AKI after elective cardiac surgery have not been identified. Objective In..
Read MoreAbstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) is an advanced therapy for patients with respiratory failure refractory to conventional management. Volume overload and elevated lactate levels have been associated..
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