Perfusfind S.L.
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Minimally invasive cardiac surgery in congenital heart diseases: the new horizon

Abstract Introduction Sternotomy has been the most common approach for the correction of congenital cardiac defects, and questions arise surrounding the safety, feasibility, and cost-effectiveness of implementing minimally invasive techniques..

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Outcomes after lung transplantation performed using elective cardiopulmonary bypass: A single-center experience

Abstract Background There remains significant variability in the use of intraoperative mechanical circulatory support in lung transplantation. This report details our outcomes using elective cardiopulmonary bypass (CPB) in lung transplantation...

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Interplay between platelet and T lymphocyte after coronary artery bypass grafting (CABG): Evidence for platelet mediated post-CABG immunomodulation

Abstract Background On-pump coronary artery bypass grafting (CABG) triggers inflammatory responses as a result of surgical stress and extracorporeal circulation, which affect platelet and leukocyte activation while enhancing their intimate..

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Red blood cell transfusion management for people undergoing cardiac surgery for congenital heart disease

Abstract Background Congenital heart disease is the most common neonatal congenital condition. Surgery is often necessary. Patients with congenital heart disease are potentially exposed to red cell transfusion preoperatively, intraoperatively..

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Impact of Different Sweep Gas Flow Rates on Respiratory Alkalosis and Cerebral Oxygenation during Cardiopulmonary Bypass

Abstract There is no consensus on the ideal sweep gas flow volume for achieving targeted blood partial gas pressures during cardiopulmonary bypass (CPB). The sweep gas flow rate is one..

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Successful Management of a Penetrating Cardiac Injury by Date Palm Thorn: A Case Report

Abstract Penetrating cardiac injury in children is a life-threatening emergency. The initial reaction of the witness and medical team management plays a crucial role in survival. We are reporting a..

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Effect of Ascorbic Acid on the Incidence of Postoperative Delirium Among Elderly Patients Undergoing Cardiovascular Surgery: A Pilot Study

Abstract Background: Ascorbic acid is a strong antioxidant that prevents postoperative delirium by inhibiting reactive oxygen species production. This pilot study was designed to investigate the prevalence of postoperative delirium among..

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Persistent Renal Hypoxia and Histologic Changes at 4 Weeks after Cardiopulmonary Bypass in Sheep

Abstract Background:  The sustained renal effects of exposure to cardiopulmonary bypass are unknown. This study aimed to test whether cardiopulmonary bypass (CPB) is associated with sustained renal tissue hypoxia and..

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A Practical Guide to Biostatistics Used in the Journal of Intensive Care Medicine

Abstract Introduction Biostatistics is an increasing focus in both the United States Medical Licensing exams (USMLE) and medical school curricula. Nonetheless, literature has documented that it is poorly understood among..

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Intraoperative Hemolysis Monitoring by Real-time Point-of-care in Patients Undergoing Cardiopulmonary Bypass in Cardiac Surgery: A Single-centre Prospective Observational Study

Abstract Objective Hemolysis is a complication in surgical procedures requiring cardiopulmonary bypass (CPB). The primary aim of this study was to evaluate the effectiveness of the point-of-care device Hemcheck Helge..

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Goal-directed Perfusion to Reduce Acute Kidney Injury After Pediatric Cardiac Operation

Abstract Background Although goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) has been discussed extensively in adult studies, no pediatric indexed oxygen delivery (Do2i) thresholds are universally accepted, and no pediatric..

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Real-time blood gas management: evaluating quantum perfusion system’s accuracy against a standard blood gas analysis in CPB

Abstract Background Continuous blood gas monitoring (CBGM) during cardiopulmonary bypass (CPB) is essential for maintaining optimal patient outcomes, enabling rapid responses to critical fluctuations in blood gas parameters. This non-inferiority..

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Outcomes of Neonatal Cardiac Surgery: A European Congenital Heart Surgeons Association Study

Abstract Background We evaluated outcomes of neonatal cardiac surgery at hospitals affiliated with the European Congenital Heart Surgeons Association (ECHSA). Methods All patients ≤30 days of life undergoing a cardiac..

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Understanding what leaders can do to facilitate healthcare workers’ feeling valued: improving our knowledge of the strongest burnout mitigator

Abstract Aim Feeling valued is a striking mitigator of burnout yet how to facilitate healthcare workers (HCWs) feeling valued has not been adequately studied. This study discovered factors relating to HCWs..

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Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery

Abstract Importance  Excessive bleeding is a common and prognostically important complication of cardiac surgery. For bleeding related to coagulation factor deficiency, frozen plasma is the most used therapy. Preliminary trials indicate..

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Exploring the Role of Immersive Virtual Reality Simulation in Health Professions Education: Thematic Analysis

Abstract Background: Although technology is rapidly advancing in immersive virtual reality (VR) simulation, there is a paucity of literature to guide its implementation into health professions education, and there are..

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Diagnosing Nosocomial Infections During Pediatric Extracorporeal Membrane Oxygenation

Abstract Nosocomial infections are one of the most frequent complications of extracorporeal membrane oxygenation (ECMO) and are associated with increased mortality (). Bloodstream infections present a particular problem because of..

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Enhancing the quality of surgical care through improved patient handover processes

Abstract Surgical handover remains a high-risk process with no gold standard for practice despite 20 years of available guidance. Variability in practice is common, and poorly performed handover poses significant,..

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Cardiac myxoma: a comprehensive review

Abstract Heart tumours are a diverse group of tumours that may present with symptoms or be discovered incidentally when a patient is being evaluated for a physical or seemingly unrelated..

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Adjunctive Fresh Frozen Plasma Versus Adjunctive Cryoprecipitate in Cardiac Surgery Patients Receiving Platelets for Perioperative Bleeding

Abstract Objective(s) This study was designed to assess the relative association between adjunctive fresh frozen plasma (FFP) or adjunctive cryoprecipitate and morbidity and mortality in cardiac surgery patients receiving platelets..

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Substrate Enhancement in Cardioplegia: Current Concepts and Future Directions

Introduction Myocardial protection during cardiac surgery is a critical determinant of patient outcomes. Traditional cardioplegia techniques primarily aim to arrest the heart, reduce metabolic demand, and preserve myocardial viability (Buckberg,..

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The Air-Blood Interface During Cardiopulmonary Bypass: Mechanisms and Clinical Implications

Introduction: Cardiopulmonary bypass, a cornerstone of modern cardiac surgery, temporarily diverts blood away from the heart and lungs, allowing for surgical intervention in a controlled environment. During CPB, blood is..

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Basic Goals of Myocardial Protection During Cardiopulmonary Bypass (CPB)

Introduction Cardiopulmonary bypass (CPB) is essential for modern cardiac surgery, allowing complex repairs and reconstructions by diverting blood away from the heart and lungs. However, during this process, the heart's..

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Inflammatory Responses During Cardiopulmonary Bypass: Mechanisms, Mediators, and Management Strategies

Abstract: Cardiopulmonary bypass (CPB) induces a multifactorial systemic inflammatory response that significantly contributes to postoperative complications such as acute lung injury, renal dysfunction, and increased morbidity. This response is initiated..

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Perfusion Physiology: The Interplay of Flow, Pressure, Hematocrit, and Oxygen Delivery.

Introduction Cardiopulmonary bypass (CPB) has revolutionized cardiac surgery by temporarily taking over the function of the heart and lungs during complex procedures. Central to this technique is the management of..

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Optimizing Filtration in Cardiopulmonary Bypass: A Comprehensive Overview

Introduction Cardiopulmonary bypass (CPB) plays a pivotal role in modern cardiac surgery by temporarily assuming the functions of the heart and lungs during complex procedures. However, despite its life-saving capabilities,..

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Aseptic Techniques in the Setup of Cardiopulmonary Bypass: Ensuring Safety in Cardiac Surgery

Introduction: Cardiac surgery is among the most delicate and high-risk procedures in modern medicine, and the use of cardiopulmonary bypass (CPB) is central to its success. In this complex setting,..

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Priming Techniques in Cardiopulmonary Bypass: An Overview.

Introduction Cardiopulmonary bypass (CPB) is a cornerstone of modern cardiac surgery, facilitating complex intracardiac procedures by temporarily assuming the function of the heart and lungs. One of the most critical..

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Cerebral Hemodynamic Monitoring via Transcranial Doppler Ultrasound and Near-Infrared Spectroscopy for Risk-Stratified Pediatric Cardiac Surgery Patients

Abstract Background The objective of this study was to evaluate mean cerebral blood flow velocity, gaseous microemboli (GME) counts, regional cerebral oxygen saturation (rSO2), and clinical outcomes using multimodality neuromonitoring..

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Sepsis-Extracorporeal Membrane Oxygenation Score in Patients Receiving Extracorporeal Membrane Oxygenation Support for Sepsis

Abstract Predictive scoring systems for adult patients receiving extracorporeal membrane oxygenation (ECMO) support for sepsis have not been yet reported. Based on the Chinese Society of ExtraCorporeal Life Support (CSECLS)..

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