Perfusfind S.L.

Abstract INTRODUCTION: Venovenous extracorporeal membrane oxygenation (VV ECMO) is a life‑saving intervention commonly used for severe and refractory respiratory failure. However, patient management and outcomes in this setting remain challenging..

Perfusfind S.L.

Abstract Adequate suppression of nociception remains a fundamental objective of modern cardiac anaesthesia. Interpretation of nociception monitoring during cardiac surgery involving cardiopulmonary bypass (CPB), however, is complicated by profound physiological..

Perfusfind S.L.

Abstract Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) occurs in 20-30% of patients after heart surgery with cardiopulmonary bypass (CPB). AKI rates are even higher in VA ECMO treated patients...

Perfusfind S.L.

Abstract Introduction Acute kidney injury is common after cardiac surgery requiring cardiopulmonary bypass, yet preventive strategies are limited. Progress has been hindered by a lack of clinically relevant experimental models..

Perfusfind S.L.

Abstract Objective The aim of this study was to investigate the maximum capacity of the Cytosorb adsorber for clearance of cell-free hemoglobin (cfHb) in a porcine cfHb solution in vitro...

Perfusfind S.L.

Abstract Introduction Deep hypothermic circulatory arrest (DHCA) is essential for pulmonary thromboendarterectomy (PTE). The optimal safe duration of DHCA remains controversial. This study evaluates the association between total DHCA duration..

Perfusfind S.L.

Abstract Background: This study aims to investigate the correlation between NIRS and S100B, and the effects of NIRS, S100B, and PerfSCORE parameters on morbidity and mortality in patients undergoing open-heart..

Perfusfind S.L.

Abstract Purpose of review Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival in selected patients with refractory cardiac arrest, but the benefit is steeply time-dependent. We examine the converging rationale for delivering..

Perfusfind S.L.

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving therapy for refractory shock; however, gastrointestinal (GI) complications have been reported in up to 50% of these patients and contribute substantially..

Perfusfind S.L.

Abstract Left ventricular assist device (LVAD) explant heart transplantation represents a metabolically vulnerable population with an increased risk for renal failure and mortality. Oxygen extraction ratio (O2ER), which integrates oxygen..

Perfusfind S.L.

Abstract Despite decades of clinical experience, the physiological rationale for extracorporeal life support (ECLS) in acute respiratory distress syndrome (ARDS) remains incompletely defined. Existing trials have primarily evaluated ECLS as..

Perfusfind S.L.

Abstract Antithrombin (AT) depletion is common in critical illness, and during venovenous extracorporeal membrane oxygenation (VV ECMO), blood–surface interactions further amplify coagulation and inflammation cascades. The prognostic value of baseline..

Perfusfind S.L.

Abstract Objective Premature infants with congenital heart disease (CHD) face high perioperative mortality and neurological risk. We evaluated whether cardiopulmonary bypass timing independently influences mortality or neurologic injury in premature..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) represents one of the most ethically challenging and clinically complex therapies used in pediatric critical care. Despite limited guidance and substantial practice variability, center-level..

Perfusfind S.L.

Abstract Background/Objectives: Preoperative anemia and iron deficiency increase transfusion risk in cardiac surgery. We evaluated outcomes associated with a Patient Blood Management (PBM) pathway and assessed the robustness of these..

Perfusfind S.L.

Abstract Background Systemic inflammatory response syndrome (SIRS) is a significant postoperative complication in older patients leading to higher morbidity and mortality rates. This study investigates the predictive value of preoperative..

Perfusfind S.L.

Abstract Background Intraoperative cell salvage is widely used in pediatric scoliosis surgery to reduce allogeneic transfusion requirements. However, its clinical effectiveness and economic impact remain uncertain. The objective of this..

Perfusfind S.L.

Abstract Purpose Out-of-bed (OOB) mobility is often expected of patients bridged to lung transplantation (LTx) on venovenous (VV) extracorporeal membrane oxygenation (ECMO), but the course of listed patients who never..

Perfusfind S.L.

Abstract Background Non-technical skills (NTS) such as teamwork, communication and leadership are essential for surgical safety, but their impact on patient outcomes is uncertain. This systematic review evaluated whether NTS..

Perfusfind S.L.

Abstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..

Perfusfind S.L.

Abstract Background & Aims Postoperative renal failure remains a major determinant of morbidity and mortality after cardiac surgery, with limited preventive pharmacological options. Enoximone, a phosphodiesterase III inhibitor with inotropic..

Perfusfind S.L.

Abstract Background Post-decannulation management of residual extracorporeal membrane oxygenation (ECMO) circuit blood is an under-standardized issue in critical care and perioperative patient blood management. Whether residual circuit blood should be..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) is associated with a high risk of neurologic injury in pediatric patients, and early detection of injury is often challenging because the clinical examination is..

Perfusfind S.L.

Abstract Introduction Myocardial injury is a significant contributor to 30-day mortality after cardiac surgery with cardiopulmonary bypass. We aimed to investigate the association between mean arterial pressure, norepinephrine use during..

Perfusfind S.L.

Abstract Objectives Long-term outcomes of emergent extracorporeal membrane oxygenation (ECMO) initiated outside the operating room remain poorly defined. We evaluated long-term outcomes after emergent ECMO support outside the operating room..

Perfusfind S.L.

Abstract I read with interest the systematic review and meta-analysis by Samaniego-Laguna et al., which addresses whether intraoperative hemoadsorption during cardiopulmonary bypass (CPB) reduces postoperative complications. The reported reduction in..

Perfusfind S.L.

Abstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..

Perfusfind S.L.

Abstract Background/Objectives: Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), increasing morbidity and prolonging hospitalization. This study aimed to develop and validate an..

Perfusfind S.L.

Abstract Thoracoabdominal normothermic regional perfusion (TA-NRP) is increasingly adopted for cardiac allograft procurement in controlled donation after circulatory death (cDCD). In settings where ante-mortem femoral guidewire placement is permitted, peripheral..

Perfusfind S.L.

Abstract In a recent edition of Anesthesiology, Wijk et al. examine the differential effect on the kidney of cardiopulmonary bypass (CPB) with flow rates of 2.4 L/min/m2 and 2.9 L/min/m2...