Perfusfind S.L.
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The American Society of ExtraCorporeal Technology Standards and Guidelines for Pediatric and Congenital Perfusion Practice: 2025 Update

Abstract Background In 2019, the American Society of Extracorporeal Technology (AmSECT) approved the inaugural Standards and Guidelines for Pediatric and Congenital Perfusion Practice. These standards and guidelines were created with the..

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Thrombocytopenia After Cardiac Surgery: A Single-Center Retrospective Study

Abstract Background: Postoperative thrombocytopenia is a frequent complication in cardiac surgery, associated with increased morbidity and mortality. Our study aimed to describe platelet count after cardiac surgery and identify predictors..

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Plasma Biomarkers of Brain Injury in Critically Ill Children Receiving Extracorporeal Membrane Oxygenation

Abstract Importance  Timely identification of acute brain injury (ABI) in children receiving extracorporeal membrane oxygenation (ECMO) support is critical for early neuroprotective interventions. Objectives  To determine if elevations in plasma glial fibrillary..

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Influence of Human Factors on Coagulation Management in Cardiac Surgery: A Retrospective Analysis

Abstract Objectives To determine if the administration of coagulation products in cardiac surgery depends on the anesthesiologist’s exposure/number of cases per year, being on-call the same night as the surgery,..

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Perioperative Management and Surgical Approaches in a Rare Case of Coronary Artery Bypass Grafting Surgery in a Patient with Takayasu’s…

Introduction Takayasu’s arteritis (TA) is an idiopathic vasculitis that mainly affects the aorta and its proximal branches. The female-to-male ratio is 8:1. The mean age at the time of diagnosis..

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Use of andexanet alfa: A British Society for Haematology position statement

Abstract Andexanet alfa (Ondexxya) currently holds UK marketing authorisation (MA) for adult patients treated with a direct factor Xa (FXa) inhibitor (apixaban or rivaroxaban) when reversal of anticoagulation is indicated..

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AI-induced never-skilling in medical education

Abstract The integration of artificial intelligence (AI) into medical training is accelerating faster than the educational frameworks designed to govern it. This Perspective identifies a risk that has received insufficient..

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Intestinal microbiota dynamics in postoperative delirium following cardiac surgery with cardiopulmonary bypass: an observational study

Abstract Background Postoperative delirium (POD) is a common complication of cardiac surgery with cardiopulmonary bypass (CPB), and it is associated with systemic inflammation and gut–brain axis dysregulation. This study investigated..

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Comprehensive Coagulation Management in Cardiac Surgery: Anticoagulants, Heparin Resistance, Monitoring, and Bleeding Risks

Abstract Effective coagulation management is pivotal to optimizing outcomes in cardiac surgery, influencing bleeding risk, transfusion requirements, and overall perioperative safety. This comprehensive review examines current strategies, limitations, and emerging..

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FXII decline during cardiopulmonary bypass and the limits of routine coagulation assays: a prospective observational analysis

Abstract Background The contact activation system is triggered when blood comes into contact with artificial surfaces. Cardiopulmonary bypass (CPB) induces such activation, however the extent of factor XII (FXII) reduction..

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A Systematic Review of How Cardiopulmonary Bypass Parameters Influence Electroencephalogram Signals

Abstract Background: Cardiopulmonary bypass (CPB) is an essential technique for cardiac surgery but significantly increases the risk of perioperative neurological complications. Electroencephalography (EEG) enables real-time monitoring of brain function and..

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Impact of an Autotransfusion Device on Platelet Count and Transfusion Requirements in Cardiac Surgery: An Observational Study

Abstract Objectives To compare postoperative platelet counts in patients in whom intraoperative cell salvage (ICS) was performed using either a centrifugation-based device (ICS-centrifugation) or a filtration-based device (ICS-filtration; Same) for..

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Next generation spray-dried on-demand plasma: A multicenter, randomized, dose-escalation, first-in-human safety study

Abstract Background Prehospital plasma transfusion for patients at risk of hemorrhagic shock reduces mortality, but cold-chain and logistical constraints limit product availability. This study reports the first-in-human clinical evaluation of..

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Hypobaric type oxygenators during cardiopulmonary bypass for cardiac surgery to reduce gaseous microemboli: A randomized controlled trial

Abstract Objectives Neurological complications after cardiac surgery have been associated with gaseous microemboli generated during cardiopulmonary bypass. We undertook a trial to assess whether a novel dual-chamber oxygenator, designed to..

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60 years of ARDS and the evolution of extracorporeal lung support – from ECMO to ECCO2R

Abstract Extracorporeal life support (ECLS), including venovenous extracorporeal membrane oxygenation (VV-ECMO) and  extracorporeal carbon dioxide removal (ECCO₂R), is an established treatment for selected patients with acute respiratory distress syndrome (ARDS)...

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Low-Dose Postoperative Amino Acid Infusion and Kidney Protection After Cardiac Surgery: A Before-and-After Observational Cohort Study

Abstract Objectives To evaluate the real-world impact of implementing routine postoperative amino acid infusion on cardiac surgery–associated acute kidney injury (AKI). Design Before-and-after study. Setting Intensive care unit (ICU). Participants..

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Evaluating Four HIT Prediction Scores After Cardiac Surgery With Cardiopulmonary Bypass: A Comparative Study

Abstract Objectives To compare the diagnostic performance of 4 clinical prediction scores for heparin-induced thrombocytopenia (HIT) in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Design Bicentric retrospective observational study...

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Master in Cardiovascular Technology, Aarhus University

The Master’s programme prepares students to acquire the knowledge, skills and competencies required to analyse and assess clinical issues within cardiovascular technology, to identify and perform clinically relevant research projects..

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Evaluation of nursing performance during coronary artery bypass grafting surgeries using machine learning analysis of surgical videos: a multicenter retrospective…

Abstract Background Coronary Artery Bypass Grafting (CABG) is a high-risk, complex cardiac procedure that relies heavily on effective nursing collaboration to ensure surgical safety and improve patient outcomes. The advancement..

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Postoperative Bleeding Definitions as the Foundation of Hemostasis in Pediatric Cardiac Surgery

Abstract Effective perioperative hemostasis in pediatric cardiac surgery depends not only on accurate diagnostics and targeted transfusion strategies but also on a clear and consistent definition of postoperative bleeding. Despite..

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Predictive value of cerebral oxygenation with near infrared spectroscopy for in-hospital mortality in pediatric congenital heart disease surgery: a retrospective…

Abstract Aim Congenital heart disease still has significant morbidity and mortality despite advances in surgery. Inadequate tissue perfusion is thought to be the primary cause. Monitoring children with cerebral oxygenation..

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Prehabilitation clinic in cardiac surgery: multidisciplinary protocol for the improvement of postoperative outcomes

Abstract Background Prehabilitation in cardiac surgery is a multidisciplinary approach aimed at optimizing the clinical and functional status of patients awaiting elective procedures. Interventions addressing nutrition, physical activity, psychological support..

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Microcirculation and Cerebrovascular Autoregulation in Patients With Mechanical Circulatory Support Devices

Abstract Acute brain injury (ABI) affects up to one-third of patients using mechanical circulatory support (MCS). In venoarterial extracorporeal membrane oxygenation (VA ECMO), ABI incidence (11%-40%) has not improved in..

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Neurological complications in veno-arterial extracorporeal membrane oxygenation and the potential role of targeted temperature management– A narrative review

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to provide circulatory support in acute cardiac failure. However, it is frequently complicated by neurological injury, which substantially worsens morbidity..

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Managing complex congenital anomalies during multi-organ donor procurement

    Managing complex congenital anomalies during multi-organ donor procurement requires precise surgical tailoring to preserve the structural integrity of the heart. When faced with a donor harboring both a..

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Microcirculation and Cerebrovascular Autoregulation in Patients With Mechanical Circulatory Support Devices

Abstract Acute brain injury (ABI) affects up to one-third of patients using mechanical circulatory support (MCS). In venoarterial extracorporeal membrane oxygenation (VA ECMO), ABI incidence (11%-40%) has not improved in..

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Determination of brain death in potential donors on ECMO support

Abstract Background A recent update of the German directive on determining brain death introduced changes regarding the diagnostics in potential donors on extracorporeal membrane oxygenation (ECMO). Physicians familiar with ECMO must..

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Teaching raters to see: A faculty development innovation for robust assessment in health professions education

Abstract Trustworthy simulation-based assessment depends on capable raters—but current approaches to rater training are often resource-intensive, inconsistently effective, and conceptually muddled. In practice, many programs focus on delivering training activities..

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Total trans septal approach and DCD rapid recovery

  Oxygenated Cardioplegia (OCP) using a blood-based vehicle represents a significant shift from traditional cold crystalloid preservation during multi-organ heart and lung procurements. By leveraging a mixture of oxygenated donor..

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Complex Heart-Lung Procurement and Back-Table Reconstruction

    Navigating the Anatomical Storm: Complex Heart-Lung Procurement and Back-Table Reconstruction   In the high-stakes arena of cardiothoracic transplantation, procurement surgery is often treated as a standardized exercise. Surgeons..

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