Tags Archives: Septic shock

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Cytokine adsorption in severe, refractory septic shock

Dear Editor, Septic shock and the underlying dysregulated inflammatory host-response remain major contributors to mortality in critically ill patients. In contrast to classic hemofiltration strategies, cytokine adsorption through bulk removal..

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Use of Cytosorb in a patient with septic shock and acute liver failure

This case reports on a 66-year-old female patient who presented to hospital for elective surgical treatment of a large right-sided renal pelvic stone. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/07/CoW_30_2021_E_web_compressed.pdf"]  

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Use of extracorporeal hemoadsorption in septic shock due to liver abscesses in the context of PSC recurrence post liver transplantation

This case reports on a 54-year-old male patient who was treated in the medical intensive care unit at Aachen University Hospital following a generalized tonic-clonic seizure with subsequent postictal vigilance..

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Hemoadsorption with CytoSorb® and the early course of linezolid plasma concentration during septic shock

This case reports on a 61-year-old woman with Ulrich Turner syndrome, who developed septic shock following right hemicolectomy. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/06/CoW_25_2021_E_web_compressed.pdf"]  

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Neurological Outcome According to the Site of Cannulation in Septic Children Supported by Venoarterial Extracorporeal Membrane Oxygenation

Abstract The impact of cervical cannulation on neurologic outcome has not been yet studied among children receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) in the context of severe sepsis or septic..

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Extracorporeal Cytokine Adsorption Therapy As a Preventive Measure in Cardiac Surgery and As a Therapeutic Add-On Treatment in Sepsis

Abstract Objectives:  Evaluating whether there is a clinical benefit of using extracorporeal cytokine adsorption therapy in two indications. Design:  Systematic review. Setting:  Search on four databases, Medline, Embase, The Cochrane..

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Dual veno-arterial extra-corporeal membrane oxygenation support in a patient with refractory hyperdynamic septic shock: a case report

Abstract The hypodynamic septic shock appears to be a promising indication to veno-arterial membrane oxygenation (VA-ECMO) support of a patient with insufficient cardiac output. With cardiac recovery most of those..

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All that glitters is not gold: an unusual presentation of S. aureus sepsis during ECMO

Abstract A 53-year-old male was submitted to veno-venous extracorporeal membrane oxygenation (ECMO) due to coronavirus disease 2019 (COVID-19) pneumonia for 84 days, without relevant complications related to the circuit itself until..

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Hemoadsorption with CytoSorb in Septic Shock Reduces Catecholamine Requirements and In-Hospital Mortality: A Single-Center Retrospective ‘Genetic’ Matched Analysis

Abstract Septic shock is a major burden to healthcare with mortality rates remaining high. Blood purification techniques aim to reduce cytokine levels and resultant organ failure. Regarding septic shock, hemoadsorption..

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Veno–veno–arterial extracorporeal membrane oxygenation treatment in patients with severe acute respiratory distress syndrome and septic shock

Abstract In acute respiratory distress syndrome (ARDS) with refractory septic shock, isolated veno–venous (VV) or veno–arterial (VA) extracorporeal membrane oxygenation (ECMO) may lead to differential hypoxia or inadequate tissue perfusion..

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Sepsis-induced myocardial dysfunction: pathophysiology and management

Abstract Sepsis is aggravated by an inappropriate immune response to invading microorganisms, which occasionally leads to multiple organ failure. Several lines of evidence suggest that the ventricular myocardium is depressed..

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Microvascular reactivity and clinical outcomes in cardiac surgery

Abstract Introduction Microvascular reactivity is decreased in patients with septic shock; this is associated with worse clinical outcomes. The objectives of the present study were to investigate microvascular reactivity in..

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Use of CytoSorb in a patient with septic shock in the context of mastitis and gangrenous cholecystitis

This report describes the case of a 63-year-old female patient, who was admitted to the Intensive Care Unit with the diagnosis of septic shock. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/03/caso-semana-cyto_compressed.pdf" title="caso semana cyto_compressed"]

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Developing a New Definition and Assessing New Clinical Criteria for Septic Shock

Abstract Importance  Septic shock currently refers to a state of acute circulatory failure associated with infection. Emerging biological insights and reported variation in epidemiology challenge the validity of this definition.Objective  To develop..

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Extracorporeal Membrane Oxygenation for Adults With Refractory Septic Shock

Abstract Because of a severe dysregulation of the host response to infection, septic shock may induce a profound imbalance between oxygen consumption and delivery, which in some cases may be..

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Use of CytoSorb in an infant with trisomy 21 and a complex heart defect, with septic shock and severe ARDS

This case reports on a 7-month-old male pediatric patient (known pre-existing conditions: trisomy 21 (also known as Downs syndrome), aortic isthmus stenosis, atrioventricular septal defect (AVSD) Rastelli type C), who..

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Use of CytoSorb in a pediatric patient with septic shock in the setting of a non-controlled infectious focus

The case study reports on a 16-year-old girl, who presented to the hospital with syncope and fever (39°C), tachycardia, complaints of chest pain and coughing after fainting at home.  ..

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Use of CytoSorb in a patient with severe ARDS and septic shock after mitral valve and tricuspid valve reconstruction

This case reports on a 79-year-old female patient who presented to the hospital for elective surgery due to severe mitral valve and tricuspid valve insufficiency.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-patient-with-severe-ARDS-and-septic-shock-after-mitral-valve-and-tricuspid-valve-reconstruction_compressed.pdf" title="Use of..

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Use of CytoSorb in a patient with septic shock after anastomosis insufficiency with abscess following pancreatic resection

This case reports on a 76-year-old male patient, who was admitted to the emergency department two weeks after an elective and initially complication-free pancreas resection with acute abdomen, signs of..

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Use of CytoSorb in a patient with mitral valve dysfunction, atypical pneumonia and mixed cardiogenic and septic shock

This case study reports on a 59-year-old patient who presented with dyspnea and weight gain of 12 kg at a peripheral hospital.    [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-patient-with-mitral-valve-dysfunction-atypical-pneumonia-and-mixed-cardiogenic-and-septic-shock_compressed.pdf" title="Use of CytoSorb in a..

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Intra- and postoperative use of CytoSorb in a patient with infective endocarditis, septic shock and myocardial infarction

This case reports on a 49-year-old previously healthy female patient, who presented to the Accident and Emergency Department of a peripheral hospital with complaints of breathlessness and fever for one..

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CytoSorb in the management of severe septic shock after coronary artery bypass graft surgery

This case reports on a 58-year-old male was hospitalized with a 2-day history of chest pain and dyspnea on exertion (New York Heart Association Class III).   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-in-the-management-of-severe-septic-shock-after-coronary-artery-bypass-graft-surgery_compressed.pdf" title="CytoSorb..

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Continuous cytokine haemoadsorption incorporated into a venoarterial ECMO circuit for the management of postcardiotomy cardiogenic and septic shock – a…

Abstract Introduction: The acute surgical treatment of infective endocarditis (IE) carries a high risk of postoperative mortality. Most complications are linked to uncontrolled sepsis and inflammatory processes. Cytokine haemoadsorption is..

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Serum lactate poorly predicts central venous oxygen saturation in critically ill patients: a retrospective cohort study

Abstract Background Serum lactate and central venous oxygen saturation (ScvO2) are commonly used and commonly recommended as markers of tissue oxygenation in shock states. Medical literature has both explicitly stated..

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Mechanisms of vascular hyporesponsiveness in septic shock

Abstract Purpose: To define some of the most common characteristics of vascular hyporesponsiveness to catecholamines during septic shock and outline current therapeutic approaches and future perspectives. Methods: Source data were obtained from..

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Vasopressin: Mechanisms of action on the vasculature in health and in septic shock

Abstract Background:  Vasopressin is essential for cardiovascular homeostasis, acting via the kidney to regulate water resorption, on the vasculature to regulate smooth muscle tone, and as a central neurotransmitter, modulating..

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Vasoplegia treatments: the past, the present, and the future

Abstract Vasoplegia is a ubiquitous phenomenon in all advanced shock states, including septic, cardiogenic, hemorrhagic, and anaphylactic shock. Its pathophysiology is complex, involving various mechanisms in vascular smooth muscle cells..

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