Tags Archives: Red Blood Cell Transfusion

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Intraoperative cell-salvaged versus allogeneic red blood cell transfusions in high-bleeding-risk cardiovascular surgery: Protocol for a single-center, randomized, parallel-group, noninferiority trial

Abstract Introduction Patients who undergo cardiac surgery have a high risk of significant blood loss and anemia. While allogeneic red blood cell (RBC) transfusions are effective, they are associated with..

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Reducing perioperative red blood cell transfusion in adult aortic surgery: innovative application and process optimization of autologous plateletpheresis

Abstract Purpose Coagulopathy is a common perioperative complication in aortic surgery, increasing the risk of bleeding and transfusion requirements. This study aimed to evaluate the impact of autologous plateletpheresis on..

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Risk–stratified outcomes of red blood cell transfusion in on–pump cardiac surgery

Abstract To the Editor: Red blood cell (RBC) transfusion is commonly performed during on-pump cardiac surgery; however, excessive use may lead to adverse clinical outcomes and medical resources wastage.[] The call..

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Storage duration of packed red blood cells transfused during veno-venous extracorporealmembrane oxygenation is associatedwith elevated pulmonary artery pressureand lung injury…

Abstract Background Veno‑venous extracorporeal membrane oxygenation (VV‑ECMO) is associated with a high transfusion burden. While trials have concluded that red blood cell (RBC) storage does not impact patient morbidity and..

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Red blood cell transfusion practices in extracorporeal membrane oxygenation: A single-center study

Abstract Objectives Evaluating blood transfusion practices and their impact on morbidity and mortality across extracorporeal membrane oxygenation (ECMO) configurations. Background As ECMO becomes increasingly utilised in critical care, the ideal..

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Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure…

Abstract Background Veno‑venous extracorporeal membrane oxygenation (VV‑ECMO) is associated with a high transfusion burden. While trials have concluded that red blood cell (RBC) storage does not impact patient morbidity and..

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Red blood cell transfusion management for people undergoing cardiac surgery for congenital heart disease

Abstract Background Congenital heart disease is the most common neonatal congenital condition. Surgery is often necessary. Patients with congenital heart disease are potentially exposed to red cell transfusion preoperatively, intraoperatively..

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Impact of implementing a nurse-led intraoperative cell saver service in reducing allogeneic red blood cell transfusions in Singapore General Hospital

Abstract Introduction Major perioperative blood loss often necessitates allogeneic blood transfusions, leading to adverse outcomes and straining healthcare resources. Intraoperative cell salvage (ICS) offers benefits like reduced adverse reactions, optimised blood..

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Development and validation of a nomogram for predicting perioperative transfusion in children undergoing cardiac surgery with CPB

Abstract Background Timely recognition of perioperative red blood cell transfusion (PRT) risk is crucial for developing personalized blood management strategies in pediatric patients. In this study, we sought to construct..

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Acute normovolemic haemodilution to reduce allogeneic red blood cell transfusion in patients undergoing coronary artery bypass grafting. An observational study

Abstract Background and Objective Patients undergoing cardiac surgery consume more than 50% of blood transfusions, and such transfusions have been associated with increased morbidity and mortality. Evidence in blood-saving techniques..

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Huaxi integrated blood management reduces the red blood cell transfusion for on-pump cardiac surgery: A quasi-experimental study

Abstract Objective As many as half of patients undergoing on-pump cardiac surgery require red blood cell transfusion, emphasizing the need for effective strategies that can reduce this need. We conducted..

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Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

Abstract Background Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of..

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Impact of a bundle of care (intravenous iron, erythropoietin and transfusion metabolic adjustment) on post-operative transfusion incidence in cardiac surgery:…

Abstract Background Red blood cell (RBC) transfusions are frequent in patients after cardiac surgery. This study assessed whether a bundle of care including pre-operative and post-operative administration of  (EPO) with intravenous..

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Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis

Abstract Background Intraoperative packed red blood cell (PRBC) transfusion during cardiac surgery is associated with increased postoperative morbidity and mortality; however, data on the association between PRBC transfusion and postoperative..

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Increased platelet to red blood cell transfusion ratio associated with acute kidney injury in children with life-threatening bleeding

Abstract Introduction Transfusion may increase the risk of organ failure through immunomodulatory effects. The primary objective of this study was to assess for patient or transfusion-related factors that are independently..

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Development and validation of a machine learning prediction model for perioperative red blood cell transfusions in cardiac surgery

Abstract Objective Several machine learning (ML) models have been used in perioperative red blood cell (RBC) transfusion risk for cardiac surgery with limited  and no external validation. Hence, we sought to..

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Preoperative Anemia and Postoperative Outcomes in Cardiac Surgery: A Mediation Analysis Evaluating Intraoperative Transfusion Exposures

Abstract BACKGROUND:  Preoperative anemia is associated with adverse outcomes in cardiac surgery, yet it remains unclear what proportion of this association is mediated through red blood cell (RBC) transfusions. METHODS: ..

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Effects of albumin and crystalloid priming strategies on red blood cell transfusions in on-pump cardiac surgery: a network meta-analysis

Abstract Background In on-pump cardiac surgery, the albumin priming strategy could maintain colloid osmotic pressure better than crystalloid solutions and reduce excessive perioperative fluid balance. However, a high-quality meta-analysis is..

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Transfusion of non–red blood cell blood products does not reduce survival following cardiac surgery

Abstract Objectives The literature supports the assertion that patients undergoing cardiac surgery who receive perioperative packed red blood cell (pRBC) transfusions have increased associated mortality. The aim of the current..

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How low can you go: Restrictive transfusion strategies in major surgery and physiological triggers

Abstract Anemia and red blood cell transfusion are associated with adverse outcomes. Large randomized trials have demonstrated that restrictive transfusion strategies can safely reduce patient exposure to transfusion, forming a..

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Effect of Red Blood Cell Transfusion on Regional Tissue Oxygenation in Pediatric Cardiac Surgery Patients

Abstract BACKGROUND:  Red blood cell (RBC) transfusions are used frequently in pediatric patients admitted to the intensive care unit (ICU) after cardiac surgery. To improve data-driven transfusion decision-making in the..

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Cerebral and intestinal oxygen saturation of different volumes of red blood cell transfusion in preterm infants

Abstract Objectives The purpose of this study was to investigate and compare the effects of 20 ml/kg and 15 ml/kg  (RBCT) on cerebral and intestinal tissue oxygenation, the number of administered transfusions, and..

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Dose-dependent influence of red blood cell transfusion volume on adverse outcomes in cardiac surgery

Abstract Introduction Red blood cell (RBC) transfusion is associated with adverse outcomes, but there are few studies on the RBC volume. This study aimed to evaluate the relationship between intraoperative..

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Determining sex-specific preoperative haemoglobin levels associated with intraoperative red blood cell transfusion in cardiac surgery: a retrospective cohort study

Abstract Background Anaemic cardiac surgery patients are at greater risk of intraoperative red blood cell transfusion. This study questions the application of the World Health Organization population-based anaemia thresholds (haemoglobin..

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Institutional Variability in Red Blood Cell Transfusion With Coronary Bypass in a Statewide Database

Abstract Background The decision to perform transfusion is common but varies among centers and surgeons. This study looked at variables associated with red blood cell (RBC) transfusion in a statewide..

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Red Blood Cell Transfusion Requirements Before and After Implementation of a Perioperative Patient Blood Management Program in Adult Patients Undergoing…

Abstract Objectives Anemia and transfusion are common in cardiac surgery patients, and are associated with significant morbidity and mortality. Multiple perioperative interventions have been described to reduce blood transfusion, but..

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Red Blood Cell Transfusion Guided by Hemoglobin Only or Integrating Perfusion Markers in Patients Undergoing Cardiac Surgery: A Systematic Review…

Abstract Objective Strategies for red blood cell (RBC) transfusion in patients undergoing cardiac surgery have been traditionally anchored to hemoglobin (Hb) targets. A more physiologic approach would consider markers of..

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Low-Volume Acute Normovolemic Hemodilution Does Not Reduce Allogeneic Red Blood Cell Transfusion in Cardiac Surgery in the Modern Era of…

Abstract Objectives Patients undergoing cardiac surgery often require , which are associated with increased morbidity and mortality. Patient blood management (PBM) strategies, including acute normovolemic  (ANH), have been implemented to minimize allogeneic..

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A transfusion risk stratification score to facilitate quality management in cardiopulmonary bypass

Abstract Background Our previous showed that a blood management program in the cardiopulmonary bypass (CPB) department, reduced red blood cell (RBC) transfusion and complications, but assessing transfusion practice solely based..

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Development of the Extracorporeal Life Support Organization International Adult Extracorporeal Membrane Oxygenation Curriculum: Creation of Initial Learning Objectives via a…

Abstract OBJECTIVES Previous studies indicated higher long-term mortality after the transfusion of allogeneic red blood cells (RBC); newer recommendations emphasize lower transfusion rates. The consequences of the transfusion of RBCs..

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