Tags Archives: Inflammatory Response

Perfusfind S.L.

Abstract Background Systemic Inflammatory Response Syndrome (SIRS) is a frequent and critical complication following cardiac surgery, particularly in patients undergoing cardiopulmonary bypass (CPB). Although SIRS is associated with increased morbidity..

Perfusfind S.L.

Abstract BACKGROUNDS  In patients with cardiac surgery under cardiopulmonary bypass (CPB), postoperative inflammation is a driver of adverse outcomes. Endotoxaemia is one of the factors thought to trigger this inflammatory..

Perfusfind S.L.

Abstract Objectives To compare the effects of total intravenous anesthesia (TIVA) versus volatile anesthesia on systemic inflammation and early postoperative cognitive recovery in pediatric patients undergoing cardiac surgery with cardiopulmonary..

Perfusfind S.L.

Abstract Objectives Minimal invasive Extracorporeal Circulation (MiECC) and Hybrid System (HS) have been introduced to potentially reduce the inflammatory response compared to conventional Cardiopulmonary Bypass (cCPB). The HS combines elements..

Perfusfind S.L.

Abstract Objectives Minimal invasive Extracorporeal Circulation (MiECC) and Hybrid System (HS) have been introduced to potentially reduce the inflammatory response compared to conventional Cardiopulmonary Bypass (cCPB). The HS combines elements..

Perfusfind S.L.

Abstract Background Antithrombin signalling may exert an anti-inflammatory effect; therefore we hypothesised that individuals with inherited antithrombin deficiency (ATD) may have an altered inflammatory state. Aims To assess the inflammatory..

Perfusfind S.L.

Abstract: Cardiopulmonary bypass (CPB) induces a multifactorial systemic inflammatory response that significantly contributes to postoperative complications such as acute lung injury, renal dysfunction, and increased morbidity. This response is initiated..

Perfusfind S.L.

Introduction Cardiopulmonary bypass (CPB) is a life-saving technology used in cardiac surgery; however, it triggers a systemic inflammatory response (SIRS) due to blood contact with non-endothelial surfaces, ischemia-reperfusion injury, and..

Perfusfind S.L.

Abstract The systemic inflammatory response after cardiopulmonary bypass has been widely studied. However, there is a paucity of studies that focus on the local inflammatory changes that occur in the..

Perfusfind S.L.

Abstract Background Extracorporeal circulation causes a systemic inflammatory response, that may cause postoperative haemodynamic instability and end-organ dysfunction. This study aimed to investigate the impact of minimal invasive extracorporeal circulation..

Perfusfind S.L.

Abstract Objectives Cardiac surgery using cardiopulmonary bypass contributes to a robust systemic inflammatory process. Local intrapericardial postsurgical inflammation is believed to trigger important clinical implications, such as postoperative atrial fibrillation..

Perfusfind S.L.

Abstract Patients undergoing coronary revascularization with extracorporeal circulation or cardiopulmonary bypass (CPB) may develop several biochemical changes in the microcirculation that lead to a systemic inflammatory response. Surgical incision, post-CPB..

Perfusfind S.L.

Abstract Objectives: Cardiopulmonary bypass (CPB) induces inflammatory homeostasis dysregulation, closely related to many postoperative adverse effects. Minimizing the systemic inflammatory response to CPB is imperative to improving cardiac surgery safety...

Perfusfind S.L.

Abstract The inflammatory response in cardiac surgery using extracorporeal circulation (ECC) has been widely discussed in the literature with analysis on cytokines released in humans. To mitigate this response mainly..

Perfusfind S.L.

Abstract Veno-venous Extracorporeal Membrane Oxygenation (ECMO) is used in the most severe cases of respiratory failure and further exacerbates the patients’ inflammatory status. Antithrombin is supplemented during ECMO for its..

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB), though indispensable in many cardiac surgery procedures, has several undesirable consequences. The aim of this study was to identify potential genes that may reduce the inflammatory..

Perfusfind S.L.

Abstract The relationship between the gut microbiome and various organ systems has gained interest throughout the scientific community in recent times. The understanding of these complex relationships has greatly improved..

Perfusfind S.L.

Abstract Introduction: Cardiopulmonary bypass causes a series of inflammatory events that have adverse effects on the outcome. The release of cytokines, including interleukins, plays a key role in the pathophysiology of..

Perfusfind S.L.

Abstract BACKGROUND:  Cardiac surgery with cardiopulmonary bypass induces a profound inflammatory response that, when severe, can lead to multiorgan system dysfunction. Preliminary data suggest that administration of hydroxyethyl starch (HES)..

Perfusfind S.L.

Abstract Aim: This study aimed to evaluate the efficacy of the resin hemoperfusion device (HA380 hemoperfusion cartridge) on inflammatory responses during adult cardiopulmonary bypass (CPB).  Methods: Sixty patients undergoing surgical valve replacement..

Perfusfind S.L.

Abstract Systemic inflammatory responses in patients undergoing extracorporeal membrane oxygenation (ECMO) contribute significantly to ECMO-associated morbidity and mortality. In recent years, the number of type 2 diabetes mellitus patients has..

Perfusfind S.L.

Abstract Low cardiac output syndrome and the systemic inflammatory response are consequences of the cardiac surgical perioperative course. The mechanisms responsible are multifactorial, but recent studies have shown that nitric..

Perfusfind S.L.

Abstract Introduction Patients subject to major surgery, suffering sepsis, major trauma, or following cardiopulmonary bypass exhibit a systemic inflammatory response. This inflammatory response involves a complex array of inflammatory polypeptide..

Perfusfind S.L.

Abstract We present a case series of seven patients with suspected cold agglutinin antibodies, discovered after initiation of bypass. Laboratory analysis of blood samples intraoperatively determined the cause of the..

Perfusfind S.L.

Abstract This review wants to give an overview to most of the controversial fields in the clinical therapeutic assistance in neonatal and pediatric general and cardiothoracic surgery in anaesthesia and..

Perfusfind S.L.

Abstract According to a survey by the University of Ottawa in 2009, we have surpassed the 50 million mark over the total number of scientific articles published since 1665, and..