Abstract Background Traumatic major limb amputations require urgent intervention to prevent irreversible tissue necrosis and life-threatening systemic complications due to warm ischemia. We aim to demonstrate the efficacy of extracorporeal..
Read MoreAbstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly used in refractory cardiogenic shock (CS) but may exacerbate left ventricular (LV) loading conditions and impair cardiac energetics. Adjunctive LV..
Read MoreAbstract Background Extracorporeal circulation (ECC) is an essential operation in many cardiac surgeries, but contact between blood and connecting tubes can activate inflammatory factors and adversely affect complement. Previous studies..
Read MoreAbstract In extracorporeal therapies such as cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO), the transport of blood through artificial circulation frequently results in the rupture of erythrocytes, releasing hemoglobin..
Read MoreAbstract Objectives To determine whether preoperative platelet (PLT) count independently predicts in-hospital mortality in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). Design Secondary analysis of a prospectively maintained institutional registry...
Read MoreAbstract Objective This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its..
Read MoreAbstract Background Acute kidney injury (AKI) is frequent in patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO), largely due to the severity of cardiogenic shock and multiorgan failure. Renal replacement..
Read MoreAbstract Background Nearly 500,000 open-heart operations are performed annually in the United States, with complications such as postcardiotomy cardiogenic shock (PCCS) occurring in 2–9% of cases. Extracorporeal membrane oxygenation (ECMO)..
Read MoreAbstract Background Patients supported with extracorporeal membrane oxygenation (ECMO) are susceptible to healthcare-associated infections (HAIs), which may worsen outcomes. However, epidemiological data from Latin American centres remain scarce. Methods We..
Read MoreAbstract Objective To characterize relationships between social determinants of health (SDoH) and mortality among infants receiving extracorporeal membrane oxygenation (ECMO). Study design Retrospectively, we identified infants born >34weeks gestation and..
Read MoreAbstract We present the first characterization of multiple organ dysfunction (OD) patterns and their associations with in-hospital mortality for children on extracorporeal membrane oxygenation (ECMO). We retrospectively assessed OD for..
Read MoreAbstract Acute kidney injury (AKI) and fluid accumulation (FA) are common during extracorporeal membrane oxygenation (ECMO) support and are associated with increased morbidity and mortality. Despite their clinical importance, contemporary..
Read MoreAbstract Introduction Bleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes..
Read MoreAbstract Decompensated differential carbon dioxide (CO2) removal can occur during spontaneous breathing on peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) when a low right radial arterial partial pressure of carbon..
Read MoreAbstract Introduction Early detection of acute brain injury (ABI) in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO) is challenging. We aimed to investigate if heart rate variability (HRV) in..
Read MoreAbstract Despite the advances in technology, new patient populations, new medications, and multiple monitoring algorithms for anticoagulation, bleeding, and thrombosis complications remain high among those receiving extracorporeal life support (ECLS)..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has increasingly been used in patients with refractory severe cardiorespiratory failure in recent years. The use of ECMO necessitates anticoagulation as blood passes through an..
Read MoreAbstract Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannulation (PC)..
Read MoreAbstract Objective To evaluate whether neighborhood-level opportunity, measured by the Child Opportunity Index (COI), is associated with short- and long-term outcomes following pediatric extracorporeal membrane oxygenation (ECMO). Design Retrospective observational..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) is a type of mechanical circulatory support that is increasingly utilised for severe cardiorespiratory failure in the intensive care unit (ICU) setting. ECMO is..
Read MoreAbstract Open thoracoabdominal aortic aneurysm repair (TAAAR) is associated with mortality rates of between 8% and 25%. One of the characteristics of TAAAR is massive bleeding that requires multiple units..
Read MoreAbstract Background Pediatric patients with combined irreversible pulmonary disease and right ventricular (RV) failure on conventional ECMO face significant challenges with rehabilitation and transplant candidacy. We describe our institutional experience..
Read MoreAbstract Extracorporeal life support, such as hemodialysis, often face the risk of blood coagulation, where systemic anticoagulation with heparin is routinely administered. However, this strategy is contraindicated in patients at..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) can trigger a systemic inflammatory response syndrome (SIRS) with activation of inflammatory, endothelial, and coagulation system pathways. We assessed in a randomized trial whether a)..
Read MoreAbstract Background: The clinical differences between intra-aortic balloon pumping (IABP) and a microaxial flow pump (Impella) for left ventricular (LV) unloading in patients with fulminant myocarditis (FM) supported with venoarterial extracorporeal..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) has been used in the care of critically ill neonates since the 1970s. Some neonatal ECMO indications include inadequate tissue oxygen delivery, severe hypoxic..
Read MoreAbstract Background: Lactic alkalosis, defined as an increase in circulating lactate in the setting of elevated extracellular pH, has been described in both in vivo and in vitro settings, often..
Read MoreAbstract Risk of limb ischemia in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) is minimized with the use of distal perfusion catheters (DPCs). However, conventional sheaths utilize a flow-limiting side..
Read MoreAbstract Objectives Hemorrhagic complications remain a major concern in patients with cardiogenic shock and extracorporeal cardiopulmonary resuscitation. The purpose of this study was to assess the effect of withholding a..
Read MoreAbstract Capnometry is a cost-efficient method of monitoring carbon dioxide (CO2) in healthcare settings, especially during mechanical ventilation and cardiopulmonary bypass. However, the utility of capnometers for studying CO2 elimination in..
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