Tags Archives: ecmo

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Use of extracorporeal circulation in multidisciplinary approach and replantation strategies for traumatic limb amputations: A case report

Abstract Background Traumatic major limb amputations require urgent intervention to prevent irreversible tissue necrosis and life-threatening systemic complications due to warm ischemia. We aim to demonstrate the efficacy of extracorporeal..

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Changes in hemodynamics, cardiac energetics, and cell signaling pathways induced by veno-arterial extracorporeal membrane oxygenation with or without left ventricular…

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly used in refractory cardiogenic shock (CS) but may exacerbate left ventricular (LV) loading conditions and impair cardiac energetics. Adjunctive LV..

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Impact of eosinophil levels on postoperative clinical outcomes in patients undergoing extracorporeal circulation: a retrospective cohort study

Abstract Background Extracorporeal circulation (ECC) is an essential operation in many cardiac surgeries, but contact between blood and connecting tubes can activate inflammatory factors and adversely affect complement. Previous studies..

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Development of a Plasma Free Hemoglobin-Adsorbing Device for Extracorporeal Therapies

Abstract In extracorporeal therapies such as cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO), the transport of blood through artificial circulation frequently results in the rupture of erythrocytes, releasing hemoglobin..

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Preoperative Platelet Count Predicts In-Hospital Mortality in Patients Supported With Venoarterial Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Cohort Study

Abstract Objectives To determine whether preoperative platelet (PLT) count independently predicts in-hospital mortality in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). Design Secondary analysis of a prospectively maintained institutional registry...

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Impact of combined ECMO - CRRT support on patient outcomes and risk factors: a multicenter retrospective study

Abstract Objective This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its..

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Integrated or Parallel Configurations for Renal Replacement Therapy in Patients on VenoArterial Extracorporeal Membrane Oxygenation, a Single Center Retrospective Study

Abstract Background Acute kidney injury (AKI) is frequent in patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO), largely due to the severity of cardiogenic shock and multiorgan failure. Renal replacement..

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Extracorporeal membrane oxygenation as a rescue measure for postcardiotomy cardiogenic shock: A retrospective observational analysis

Abstract Background Nearly 500,000 open-heart operations are performed annually in the United States, with complications such as postcardiotomy cardiogenic shock (PCCS) occurring in 2–9% of cases. Extracorporeal membrane oxygenation (ECMO)..

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Epidemiology and outcomes of nosocomial infections in patients undergoing extracorporeal membrane oxygenation support: an eight-year retrospective cohort study

Abstract Background Patients supported with extracorporeal membrane oxygenation (ECMO) are susceptible to healthcare-associated infections (HAIs), which may worsen outcomes. However, epidemiological data from Latin American centres remain scarce. Methods We..

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Neonatal extracorporeal membrane oxygenation outcomes according to social determinants of health

Abstract Objective To characterize relationships between social determinants of health (SDoH) and mortality among infants receiving extracorporeal membrane oxygenation (ECMO). Study design Retrospectively, we identified infants born >34weeks gestation and..

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Patterns of Multiple Organ Dysfunction in Children on Extracorporeal Membrane Oxygenation Support

Abstract We present the first characterization of multiple organ dysfunction (OD) patterns and their associations with in-hospital mortality for children on extracorporeal membrane oxygenation (ECMO). We retrospectively assessed OD for..

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The Design of Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease Extracorporeal Membrane Oxygenation Study

Abstract Acute kidney injury (AKI) and fluid accumulation (FA) are common during extracorporeal membrane oxygenation (ECMO) support and are associated with increased morbidity and mortality. Despite their clinical importance, contemporary..

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Association between platelet indices and next-day bleeding and clotting in children and adults on extracorporeal membrane oxygenation: A retrospective study

Abstract Introduction Bleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes..

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Decompensated Differential Carbon Dioxide Removal During Venoarterial Extracorporeal Membrane Oxygenation: A Physiologic Framework

Abstract Decompensated differential carbon dioxide (CO2) removal can occur during spontaneous breathing on peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) when a low right radial arterial partial pressure of carbon..

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Enhancing early detection of acute brain injury using heart rate variability in patients on venoarterial extracorporeal membrane oxygenation

Abstract Introduction Early detection of acute brain injury (ABI) in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO) is challenging. We aimed to investigate if heart rate variability (HRV) in..

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Improving bleeding and thrombosis in patients with extracorporeal life support: could hematology help?

Abstract Despite the advances in technology, new patient populations, new medications, and multiple monitoring algorithms for anticoagulation, bleeding, and thrombosis complications remain high among those receiving extracorporeal life support (ECLS)..

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Monitoring Hemostatic Function During Extracorporeal Membrane Oxygenation with Point-of-Care Viscoelastic Assays: A Narrative Review

Abstract Extracorporeal membrane oxygenation (ECMO) has increasingly been used in patients with refractory severe cardiorespiratory failure in recent years. The use of ECMO necessitates anticoagulation as blood passes through an..

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Percutaneous Versus Surgical Cannulation for Veno-Arterial Extracorporeal Life Support: A Systematic Review and Meta-Analysis

Abstract Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannulation (PC)..

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Neighborhood Opportunity and Long-Term Outcomes Following Pediatric Extracorporeal Membrane Oxygenation

Abstract Objective To evaluate whether neighborhood-level opportunity, measured by the Child Opportunity Index (COI), is associated with short- and long-term outcomes following pediatric extracorporeal membrane oxygenation (ECMO). Design Retrospective observational..

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The roles and responsibilities of an advanced practice nursing team for coordinating extracorporeal life support in intensive care: A qualitative…

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a type of mechanical circulatory support that is increasingly utilised for severe cardiorespiratory failure in the intensive care unit (ICU) setting. ECMO is..

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Use of extracorporeal membrane oxygenation with a cardiotomy reservoir for patient blood management in thoracoabdominal open surgery: A single centre…

Abstract Open thoracoabdominal aortic aneurysm repair (TAAAR) is associated with mortality rates of between 8% and 25%. One of the characteristics of TAAAR is massive bleeding that requires multiple units..

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Rethinking paracorporeal lung assist device support in the modern era: Why so different than ECMO?

Abstract Background Pediatric patients with combined irreversible pulmonary disease and right ventricular (RV) failure on conventional ECMO face significant challenges with rehabilitation and transplant candidacy. We describe our institutional experience..

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Biomechanical anticoagulation by spherical platelets in extracorporeal systems

Abstract Extracorporeal life support, such as hemodialysis, often face the risk of blood coagulation, where systemic anticoagulation with heparin is routinely administered. However, this strategy is contraindicated in patients at..

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Sweep Flow Nitric Oxide Effects on Coagulation, Inflammation, and Endothelial System Activation During Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) can trigger a systemic inflammatory response syndrome (SIRS) with activation of inflammatory, endothelial, and coagulation system pathways. We assessed in a randomized trial whether a)..

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Short-Term Outcomes of Intra-Aortic Balloon Pump vs. Microaxial Flow Pump for Fulminant Myocarditis Supported by Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: The clinical differences between intra-aortic balloon pumping (IABP) and a microaxial flow pump (Impella) for left ventricular (LV) unloading in patients with fulminant myocarditis (FM) supported with venoarterial extracorporeal..

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Trends in Neonatal Extracorporeal Membrane Oxygenation (ECMO) in New York State: 2018-2024

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) has been used in the care of critically ill neonates since the 1970s. Some neonatal ECMO indications include inadequate tissue oxygen delivery, severe hypoxic..

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Lactic alkalosis in a patient on veno-venous extracorporeal membrane oxygenation: A case report

Abstract Background: Lactic alkalosis, defined as an increase in circulating lactate in the setting of elevated extracellular pH, has been described in both in vivo and in vitro settings, often..

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Novel Use of a Distal Perfusion Catheter With a Removable Side Port in Patients on VA-ECMO

Abstract Risk of limb ischemia in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) is minimized with the use of distal perfusion catheters (DPCs). However, conventional sheaths utilize a flow-limiting side..

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Heparin Exposure Adjustment to Reduce Thrombo-hemorrhagic Complications After Venoarterial Extracorporeal Membrane Oxygenator Cannulation: The HEART-ECMO Observational Cohort Study

Abstract Objectives Hemorrhagic complications remain a major concern in patients with cardiogenic shock and extracorporeal cardiopulmonary resuscitation. The purpose of this study was to assess the effect of withholding a..

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Clinical characterization of membrane oxygenator exhaust capnometry during venovenous extracorporeal membrane oxygenation

Abstract Capnometry is a cost-efficient method of monitoring carbon dioxide (CO2) in healthcare settings, especially during mechanical ventilation and cardiopulmonary bypass. However, the utility of capnometers for studying CO2 elimination in..

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