Abstract Background The use of extracorporeal membrane oxygenation (ECMO) has expanded for severe respiratory and circulatory failure. Acute kidney injury (AKI) is one of the most frequent complications. Up to..
Read MoreAbstract Background This systematic review and meta-analysis evaluated the clinical efficacy and safety of hemoperfusion in adults receiving extracorporeal membrane oxygenation (ECMO). Methods We systematically searched PubMed, Embase, the Cochrane..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is an established life-saving therapy for severe acute respiratory distress syndrome and cardiogenic shock, yet it profoundly alters cardiopulmonary physiology and challenges conventional hemodynamic monitoring...
Read MoreAbstract Adult venoarterial extracorporeal membrane oxygenation (VA ECMO) is a costly life support therapy, where patient selection remains a significant hinge-point in determining patient outcomes. Despite this, few sites have..
Read MoreAbstract Acute limb ischemia (ALI) remains one of the most common complications of peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO). Across heterogeneous cohorts, reported ALI rates vary widely (≈8–30% and..
Read MoreAbstract Peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) and minimally invasive cardiac surgery often require femoral arterial cannulation, wherein lower limb ischemia remains a major complication. Although introducer sheaths with side..
Read MoreAbstract Clot-fibrinolysis waveform analysis (CFWA) enables the simultaneous assessment of coagulation and fibrinolytic functions within a short timeframe. We evaluated the effects of commonly used anticoagulants on coagulation–fibrinolysis balance using..
Read MoreAbstract Objectives: To evaluate the cost-effectiveness of implementing an extracorporeal cardiopulmonary resuscitation (ECPR) strategy for refractory out-of-hospital cardiac arrest (OHCA) compared with current practice in Singapore, where it is not..
Read MoreAbstract For pregnant patients with severe coronavirus disease 2019 (COVID-19) requiring veno-venous (V-V) extracorporeal membrane oxygenation (ECMO), the ideal timing of delivery is uncertain, particularly when complicated by cardiogenic shock...
Read MoreAbstract Clinical Criteria and Assessment (Hypotension, Hypoperfusion, Rising Lactate, and Escalating Vasopressors) Profound hypotension, ongoing CS despite optimal medical treatment, escalating vasopressor requirements, rapidly deteriorating cardiac function, worsening lactic acidosis,..
Read MoreAbstract Introduction Critically ill ECMO patients face high bleeding risks from anticoagulation and other factors. Although viscoelastic tests, like ROTEM, are widely used to assess hemostasis, evidence for their superiority..
Read MoreAbstract Neonatal fluid management in extracorporeal life support (ECLS) is complex, with the goal of improving outcomes while preventing complications. This study evaluates the impact of early continuous renal replacement..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has become an essential supportive therapy for patients with severe respiratory and/or cardiac failure. While conventional configurations such as veno-venous and veno-arterial ECMO have well-established..
Read MoreAbstract Background The relationship between lactate-to-albumin ratio (LAR) and mortality in patients with cardiogenic etiology undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) remains unclear. Against this backdrop, the present study is..
Read MoreAbstract Background Postcardiotomy cardiogenic shock (PCS) is a life-threatening complication after adult cardiac surgery that frequently necessitates venoarterial extracorporeal membrane oxygenation (VA-ECMO). Central and peripheral VA-ECMO cannulation strategies generate distinct..
Read MoreAbstract While veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become central in the management of patients in advanced stages of cardiogenic shock due to its relative ease of deployment, there..
Read MoreAbstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive disease that occurs due to fibrotic remodeling of the pulmonary vessels. This leads to increased pressure overload onto the right ventricle,..
Read MoreAbstract Introduction Standard anticoagulation protocols for patients with trauma-related acute respiratory distress syndrome (TR-ARDS) undergoing venovenous extracorporeal membrane oxygenation (VV-ECMO) are often inapplicable due to high bleeding risks. This study..
Read MoreAbstract The role of extracorporeal membrane oxygenation (ECMO) in neonates with congenital anomalies of the kidney and urinary tract (CAKUT) remains one of the more contested frontiers at the intersection..
Read MoreAbstract Background/Objectives: Adult patients supported with extracorporeal membrane oxygenation (ECMO) frequently require invasive diagnostic, therapeutic, surgical, or bedside procedures during ongoing extracorporeal support. These procedures are clinically challenging because ECMO-related anticoagulation,..
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) has become a vital life-support tool in critical care, particularly during the COVID-19 pandemic. The rapid growth of ECMO research necessitates bibliometric analysis to..
Read MoreAbstract Background: The aim of this study was to assess the long-term outcomes of patients treated with intra-aortic balloon pump (IABP) alone and in combination with extracorporeal membrane oxygenation (ECMO),..
Read MoreAbstract Background In patients receiving extracorporeal membrane oxygenation (ECMO), standard practice is full-dose intravenous unfractionated heparin (UFH) targeting an activated partial thromboplastin time of 2·0–2·5 times baseline to reduce thrombotic..
Read MoreAbstract Purpose Obesity is increasingly encountered among patients requiring extracorporeal membrane oxygenation (ECMO) for severe respiratory or cardiac failure. It alters respiratory and cardiovascular physiology and drug pharmacokinetics and introduces..
Read MoreAbstract Hospital-acquired infection (HAI) is a major complication in pediatric patients on extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). Infection detection is challenging, as traditional inflammatory markers..
Read MoreAbstract Background Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is used for refractory cardiogenic shock, yet optimal weaning strategies and the role of left ventricular (LV) venting remain unclear. The TWEET-1..
Read MoreAbstract Background Patients receiving extracorporeal membrane oxygenation (ECMO) are considered nutritionally vulnerable, with previous studies focussed on Intensive Care Unit (ICU) admission alone. We aimed to address this gap by..
Read MoreAbstract Objective To evaluate the feasibility and diagnostic yield of universal genome sequencing (GS) in infants receiving extracorporeal membrane oxygenation (ECMO). Study design Prospective multicenter study across eight Children’s Hospital..
Read MoreAbstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis..
Read MoreAbstract Background: Invasive ventilation saves lives but carries major risks, including ventilation-associated lung damage and long-term functional impairment. Data from recent studies compel reassessment of the evidence for every step of..
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