Tags Archives: assist device

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Marginal Band Collapsing: Structural Insights Into Shear-Induced Platelet Activation Relevant to Circulatory Assist Devices

Abstract Shear-induced platelet activation and receptor shedding in mechanical circulatory support (MCS) paradoxically increase risks of thrombosis and bleeding. Although flow cytometry commonly assesses platelet activation and receptor expression, correlations..

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A Novel Low-Profile Full-Flow Percutaneous Ventricular Assist Device

Abstract Percutaneous ventricular assist devices (pVAD) decrease mortality in cardiogenic shock (CS) patients, but at a high adverse event rate. Novel pVADs need to improve cardiac power output (CPO) to..

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A Canadian Experience With a Percutaneous Microaxial Ventricular Assist Device in Children With Cardiogenic Shock

Abstract Background The experience of a percutaneous microaxial (Impella)  in children with  is limited. The primary objective of this study was to review our institutional clinical outcomes of Impella use in children..

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Blood perfusion through ventricular assist devices induces erythrocytes to interact with leukocytes

Abstract Implantations of  (VADs) have significantly improved  and life expectancy of end-stage heart failure patients. However, despite the advancements in the VAD designs and patient management protocols, the VAD recipients remain at..

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Cardiac ECMO: changing role in times of Impella and ventricular assist devices?

Abstract Mortality in infarct-related as well as heart failure-associated cardiogenic shock remains high, reaching 40–50% depending on the etiology and severity of cardiogenic shock. Percutaneous active mechanical circulatory support devices..

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Left ventricular assist device implants in patients on extracorporeal membrane oxygenation: do we need cardiopulmonary bypass?

Abstract     OBJECTIVES Implanting a durable left ventricular assist device (LVAD) in a patient on extracorporeal life support (ECLS) is challenging. The goal of this study was to compare..

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