Tags Archives: Antiphospholipid Syndrome

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Anticoagulation Management of Patients with Antiphospholipid Syndrome Undergoing Cardiopulmonary Bypass in Cardiac Surgery: Challenges and Current Strategies

Abstract The antiphospholipid syndrome (APS) is a complex autoimmune disease that causes a state of hypercoagulability that can result in recurrent venous and arterial thromboses. APS may lead to cardiac..

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Simulation-based activated clotting time targeting for cardiopulmonary bypass in patients with antiphospholipid syndrome: two case reports

Abstract Background Antiphospholipid syndrome (APS) is an autoimmune prothrombotic disorder that is frequently associated with systemic lupus erythematosus (SLE). Cardiac surgery in patients with APS presents unique challenges because activated..

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The Pathophysiology of The Antiphospholipid Syndrome: A Perspective From The Blood Coagulation System

Abstract The antiphospholipid syndrome (APS), a systemic autoimmune disease characterized by a hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused by the presence of antiphospholipid antibodies such as..

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Antiphospholipid Syndrome and Cardiac Bypass: The Careful Balance between Clotting and Bleeding

Abstract Antiphospholipid syndrome (APS) is an acquired autoimmune condition characterized by the presence of antiphospholipid antibodies (lupus anticoagulant, anticardiolipin antibody, and anti-β2 glycoprotein-I antibody) which leads to clinical thrombosis via a..

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Severe antiphospholipid syndrome and cardiac surgery: Perioperative management

Abstract Antiphospholipid syndrome is an antiphospholipid antibody-mediated prothrombotic state leading to arterial and venous thrombosis. This condition alters routine in-vitro coagulation tests, making results unreliable. Antiphospholipid syndrome patients requiring cardiac..

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Pitfalls of Commonly Used Anticoagulation Monitoring Techniques in Antiphospholipid Syndrome During Cardiopulmonary Bypass

Abstract Antiphospholipid Syndrome (APS) is an immunologic disorder that causes a state of hypercoagulability that can result in recurrent venous and arterial thromboses. Patients who experience APS may develop cardiac..

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