Abstract Anticoagulants are widely used to prevent and treat thrombotic disorders, and continuous advances have refined their efficacy and safety. Beyond their established anticoagulant function, growing evidence indicates that some..
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Abstract Coating strategies play a pivotal role in anticoagulation management during extracorporeal circulation. While heparin-based coatings remain the most widely used, their limited anticoagulant efficacy may lead to adverse events..
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Abstract The anticoagulant proteins antithrombin, protein C, protein S, and tissue factor pathway inhibitor are physiological regulators of the blood coagulation pathway and have complex roles in causing or modifying..
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Covalent Organic Framework-Based Porous Anticoagulant Materials for Extracorporeal Blood Circulation
Abstract Preventing coagulation during extracorporeal blood circulation is critical for clinical treatments. Developing anticoagulant materials for key components can reduce reliance on systemic anticoagulants and improve safety. However, such materials..
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Abstract Extracorporeal membrane oxygenation (ECMO) is the most important support for patients with severe cardiopulmonary failure. As the key component, the oxygenation membrane has suffered the risk of blood coagulation..
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Abstract Artificial lung membrane as extracorporeal blood-gas barriers could execute similar functions as human alveoli, whereby accomplish blood gas exchange process, providing imperative life support for patients with cardiopulmonary failure...
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Abstract Purpose: To evaluate unfractionated heparin (UFH) dosing guided by antifactor Xa levels during targeted temperature management (TTM) post-cardiac arrest. Methods: Single-center, retrospective, observational study between January 1, 2014 and..
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Abstract Introduction Unfractionated heparin is widely used as an anticoagulant for extracorporeal life support (ECLS) and usually monitored with activated partial thromboplastin time (aPTT). Due to its limitations in pediatric..
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Abstract For cardiopulmonary bypass, the polyvinyl chloride (PVC) circuit which can initiate the activation of platelets and the coagulation cascade after blood cell contacting is the possible detrimental effect. Surface..
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Abstract This present study explains chronic thromboemboli pulmonary hypertension in a patient with eisenmenger syndrome and large patent ductus arteries. Chronic thromboemboli pulmonary hypertension (CTEPH) is group 4 of pulmonary hypertension, related to..
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