Tags Archives: Acute kidney injury (AKI)

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Risk Factors for Acute Kidney Injury Following Cardiac Surgery and Performance of Leicester Score in a Spanish Cohort

Abstract The incidence of acute kidney injury following cardiac surgery (CSA-AKI) is up to 30%, and it places patients at an increased risk of death. The Leicester score (LS) is..

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Use of CytoSorb in a case of Salmonella typhi–induced gastroenteritis with sepsis associated acute kidney injury

This case reports on a 54-year-old female patient with a known medical history of diabetes mellitus, hypertension and acute gastroenteritis, who was admitted to the hospital with tachycardia (145/min), tachypnea..

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Effect of intrarenal renin-angiotensin-aldosterone system on renal function in patients after cardiac surgery

Abstract The aim of the study was to investigate the influence of intrarenal RAS on the decrease of renal function in patients undergoing cardiac surgery with cardiopulmonary bypass. This observational..

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Blood pressure variability during pediatric cardiac surgery is associated with acute kidney injury

Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..

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Goal-directed perfusion for reducing acute kidney injury in cardiac surgery: A systematic review and meta-analysis

Abstract Background Acute kidney injury (AKI) is a common complication following cardiopulmonary bypass (CPB) which can affect morbidity and mortality. Goal-directed perfusion (GDP) intended to avoid the nadir oxygen delivery..

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Case Report: Prevention of Rhabdomyolysis-Associated Acute Kidney Injury by Extracorporeal Blood Purification with CytoSorb®

This case reports on a 12-year-old boy, who was hit by a motorcycle while riding his bicycle. The motorcycle ran over the boy’s legs causing an open wound in the..

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Extracorporeal Life Support Organization Guidelines for Fluid Overload, Acute Kidney Injury, and Electrolyte Management

Abstract This guideline for extracorporeal membrane oxygenation (ECMO) fluid and electrolyte management for all patient populations is intended for educational use to build the knowledge of physicians and other health..

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Magnetic levitation pumps for cell-free hemoglobin prevention during VV ECMO

Abstract Increased plasma concentrations of circulating cell-free hemoglobin (CFH) are supposed to contribute to the multifactorial etiology of acute kidney injury (AKI). In their recent article: “The role of cell-free..

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Prediction of the severity of acute kidney injury after on-pump cardiac surgery

Abstract Study objective On-pump cardiac surgery is associated with a high risk of acute kidney injury (AKI), which can substantially affect risk of mortality and morbidity depending on its severity...

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Association of urine output during cardiopulmonary bypass and postoperative acute kidney injury in patients undergoing coronary artery bypass graft

Abstract Introduction Acute kidney injury (AKI) is a common complication in patients undergoing coronary artery bypass graft (CABG) surgery and is associated with significant morbidity and mortality. We investigated the..

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Modeling acid-base balance for in-series extracorporeal carbon dioxide removal and continuous venovenous hemofiltration devices

Abstract Patients with acute respiratory distress syndrome and acute kidney injury (AKI) treated by kidney replacement therapy may also require treatment with extracorporeal carbon dioxide removal (ECCO2R) devices to permit..

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To RAP or Not to RAP: A Retrospective Comparison of the Effects of Retrograde Autologous Priming

Abstract Retrograde autologous priming (RAP) is a process used to reduce hemodilution associated with the initiation of cardiopulmonary bypass (CPB). Previous studies have reported potential benefits to RAP; however, many..

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‘Goal-directed extracorporeal circulation: transferring the knowledge and experience from daily cardiac surgery to extracorporeal membrane oxygenation’

Abstract Metabolism management plays an essential role in extracorporeal technologies. There are different metabolic management devices integrated to extracorporeal devices; the most commonly used and accepted metabolic target in adult..

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Impact of partial pressure of oxygen trajectories on the incidence of acute kidney injury in patients undergoing cardiopulmonary bypass

Abstract Background To investigate the impact of the dynamic oxygenation status on the incidence of acute kidney injury (AKI) in patients undergoing cardiopulmonary bypass. Methods This retrospective study was performed..

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Gelatin and the risk of acute kidney injury after cardiac surgery

Abstract Background Gelatin has been used as a plasma volume expander because of its ability to preserve intravascular volume more effectively than crystalloids. However, gelatin may have detrimental effects on..

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Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury

Abstract Background Erythrocyte transfusions are independently associated with acute kidney injury. Kidney injury may be consequent to the progressive hematologic changes that develop during storage. This study therefore tested the..

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The Role of Race on Acute Kidney Injury Following Cardiac Surgery

Abstract Background Acute kidney injury (AKI) frequently complicates cardiac surgery and is more common among Black patients. We evaluated determinants of race-based differences in AKI rates. Methods Serum creatinine-based criteria..

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Plasma from patients undergoing coronary artery bypass graft surgery does not activate endothelial cells under shear stress in vitro

Abstract Background: Cardiac surgery with cardiopulmonary bypass (CPB) is commonly associated with acute kidney injury, and microvascular endothelial inflammation is a potential underlying mechanism. We hypothesized that pro-inflammatory components of..

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Ultrafiltration and cardiopulmonary bypass associated acute kidney injury: A systematic review and meta-analysis

Abstract Background Cardiopulmonary bypass is known to raise the risk of acute kidney injury (AKI). Previous studies have identified numerous risk factors of cardiopulmonary bypass including the possible impact of..

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Impact of partial pressure of oxygen trajectories on the incidence of acute kidney injury in patients undergoing cardiopulmonary bypass

Abstract Background To investigate the impact of the dynamic oxygenation status on the incidence of acute kidney injury (AKI) in patients undergoing cardiopulmonary bypass. Methods This retrospective study was performed..

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Prediction of acute kidney injury after cardiac surgery from preoperative N-terminal pro-B-type natriuretic peptide

Abstract Background  (AKI) is common after cardiac surgery and is difficult to predict. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is highly predictive for perioperative cardiovascular complications and may also predict renal..

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Under-recognition of Acute Kidney Injury after Cardiac Surgery in the ICU Impedes Early Detection and Prevention

Abstract Background: Acute kidney injury (AKI) is associated with high morbidity and mortality; therefore, prevention is important. The aim of this study was to systematically assess AKI incidence after cardiac surgery..

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Extracorporeal Membrane Oxygenation and Continuous Kidney Replacement Therapy: Technology and Outcomes – A Narrative Review

Abstract The number of patients using critical care is increasing as our populations live longer thanks to advances in medical therapies. This is reflected by an increase in both usage..

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Factors for Acute Kidney Injury Following Total Arch Replacement and Association with Temperature Management During Cardiopulmonary Bypass: A Single-center Retrospective…

Abstract Many patients develop acute kidney injury (AKI) after vascular surgery. In this retrospective observational study, we investigated the risk factors for AKI defined using the Kidney Disease Improving Global..

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Prediction Scores for Any-Stage and Stage-3 Acute Kidney Injury After Adult Cardiac Surgery in a Chinese Population

Abstract Objectives This study was performed to internally derive and then validate risk score systems using preoperative and intraoperative variables to predict the occurrence of any-stage (stage 1, 2, 3)..

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Renal function and inflammatory response in neonates undergoing cardiac surgery with or without antegrade cerebral perfusion—a post hoc analysis

Abstract Background: Cardiopulmonary bypass (CPB) may lead to tissue hypoxia, inflammatory response, and risk for acute kidney injury (AKI). We evaluated the prevalence of AKI and inflammatory response in neonates undergoing..

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Low Mean Arterial Pressure During Cardiopulmonary Bypass and the Risk of Acute Kidney Injury: A Propensity Score Matched Observational Study

Abstract Introduction Low mean arterial pressure (MAP) periods occur frequently during cardiopulmonary bypass (CPB), and their management remains controversial. Our aim was to correlate MAP during CPB with the occurrence..

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Association Between Exogenous Nitric Oxide Given During Cardiopulmonary Bypass and the Incidence of Postoperative Kidney Injury in Children.

Abstract Objective To compare the incidence and severity of acute kidney injury following open heart surgery with cardiopulmonary bypass in children after administration of exogenous nitric oxide. Design Retrospective cohort..

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Strategies to Prevent Acute Kidney Injury after Pediatric Cardiac Surgery

Abstract Background and objectives AKI is a common complication after pediatric cardiac surgery and has been associated with higher morbidity and mortality. We aimed to compare the efficacy of available pharmacologic..

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Brain and Muscle Oxygen Saturation Combined with Kidney Injury Biomarkers Predict Cardiac Surgery Related Acute Kidney Injury

Abstract Background: Early identification of patients at risk for cardiac surgery-associated acute kidney injury (CS-AKI) based on novel biomarkers and tissue oxygen saturation might enable intervention to reduce kidney injury...

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