Tags Archives: Acute kidney injury (AKI)

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Prediction of acute kidney injury risk after cardiac surgery: using a hybrid machine learning algorithm

Abstract Background Acute kidney injury (AKI) is a serious complication after cardiac surgery. We derived and internally validated a Machine Learning preoperative model to predict cardiac surgery-associated AKI of any severity and..

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Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury

Abstract Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI, renal replacement therapy (RRT) is deployed to address metabolic dysfunction and volume excess until..

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The successful application of hemoadsorption for extracorporeal liver support in a child with acute liver failure

This case reports on a 6-year-old boy, who was admitted to the hospital due to prolonged dyskinetic movements resulting in rhabdomyolysis and acute kidney injury [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/08/CoW_33_2022_E-web_compressed.pdf"]

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Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury

Abstract Acute kidney injury (AKI) is a common cause of morbidity after congenital heart disease surgery. Progress on diagnosis and therapy remains limited, however, in part due to poor mechanistic..

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Utility of plasma NGAL for the diagnosis of AKI following cardiac surgery requiring cardiopulmonary bypass: a systematic review and meta-analysis

Abstract The objective of this study was to assess the diagnostic value of plasma neutrophil gelatinase-associated lipocalin (pNGAL) for the early diagnosis of acute kidney injury (AKI) in adult patients..

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Comparison of different metrics of cerebral autoregulation in association with major morbidity and mortality after cardiac surgery

Abstract Background Cardiac surgery studies have established the clinical relevance of personalised arterial blood pressure management based on cerebral autoregulation. However, variabilities exist in autoregulation evaluation. We compared the association..

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Society of Cardiovascular Anesthesiologists Clinical Practice Update for Management of Acute Kidney Injury Associated With Cardiac Surgery

Abstract Cardiac surgery-associated acute kidney injury (CS-AKI) is common and is associated with increased risk for postoperative morbidity and mortality. Our recent survey of the Society of Cardiovascular Anesthesiologists (SCA)..

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Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI

Abstract Acute kidney injury (AKI) is common after cardiac surgery. To date, there are no specific pharmacological therapies. In this review, we summarise the existing evidence for prevention and management..

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Oxygen Delivery in Pediatric Cardiac Surgery and its Association with Acute Kidney Injury using Machine Learning

Abstract Objective Acute kidney injury (AKI) following pediatric cardiac surgery with cardiopulmonary bypass is a frequently reported complication. This study aims to determine the critical oxygen delivery (DO2i) threshold associated..

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Gelatin and the risk of acute kidney injury after cardiac surgery

Abstract Background Gelatin has been used as a plasma volume expander because of its ability to preserve intravascular volume more effectively than crystalloids. However, gelatin may have detrimental effects on..

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Continuous renal replacement therapy in patients treated with extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy utilized for patients with severe life-threatening cardiorespiratory failure. Patients treated with ECMO are among the most severely ill encountered in critical..

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Association Between Preoperative Statin Exposure and Acute Kidney Injury in Adult Patients Undergoing Cardiac Surgery

Abstract Objectives The existing literature has shown conflicting results regarding the association between preoperative statin exposure and the risk of postoperative cardiac surgery–associated  (CSA-AKI). Design A single-center retrospective observational study. Setting..

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Intraoperative Hypotension and Acute Kidney Injury, Stroke, and Mortality during and outside Cardiopulmonary Bypass: A Retrospective Observational Cohort Study

Abstract Background In cardiac surgery, the association between hypotension during specific intraoperative phases or vasopressor-inotropes with adverse outcomes remains unclear. This study’s hypothesis was that intraoperative hypotension duration throughout the..

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Risk Factors for Acute Kidney Injury Following Cardiac Surgery and Performance of Leicester Score in a Spanish Cohort

Abstract The incidence of acute kidney injury following cardiac surgery (CSA-AKI) is up to 30%, and it places patients at an increased risk of death. The Leicester score (LS) is..

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Use of CytoSorb in a case of Salmonella typhi–induced gastroenteritis with sepsis associated acute kidney injury

This case reports on a 54-year-old female patient with a known medical history of diabetes mellitus, hypertension and acute gastroenteritis, who was admitted to the hospital with tachycardia (145/min), tachypnea..

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Effect of intrarenal renin-angiotensin-aldosterone system on renal function in patients after cardiac surgery

Abstract The aim of the study was to investigate the influence of intrarenal RAS on the decrease of renal function in patients undergoing cardiac surgery with cardiopulmonary bypass. This observational..

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Blood pressure variability during pediatric cardiac surgery is associated with acute kidney injury

Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..

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Goal-directed perfusion for reducing acute kidney injury in cardiac surgery: A systematic review and meta-analysis

Abstract Background Acute kidney injury (AKI) is a common complication following cardiopulmonary bypass (CPB) which can affect morbidity and mortality. Goal-directed perfusion (GDP) intended to avoid the nadir oxygen delivery..

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Case Report: Prevention of Rhabdomyolysis-Associated Acute Kidney Injury by Extracorporeal Blood Purification with CytoSorb®

This case reports on a 12-year-old boy, who was hit by a motorcycle while riding his bicycle. The motorcycle ran over the boy’s legs causing an open wound in the..

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Extracorporeal Life Support Organization Guidelines for Fluid Overload, Acute Kidney Injury, and Electrolyte Management

Abstract This guideline for extracorporeal membrane oxygenation (ECMO) fluid and electrolyte management for all patient populations is intended for educational use to build the knowledge of physicians and other health..

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Magnetic levitation pumps for cell-free hemoglobin prevention during VV ECMO

Abstract Increased plasma concentrations of circulating cell-free hemoglobin (CFH) are supposed to contribute to the multifactorial etiology of acute kidney injury (AKI). In their recent article: “The role of cell-free..

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Prediction of the severity of acute kidney injury after on-pump cardiac surgery

Abstract Study objective On-pump cardiac surgery is associated with a high risk of acute kidney injury (AKI), which can substantially affect risk of mortality and morbidity depending on its severity...

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Association of urine output during cardiopulmonary bypass and postoperative acute kidney injury in patients undergoing coronary artery bypass graft

Abstract Introduction Acute kidney injury (AKI) is a common complication in patients undergoing coronary artery bypass graft (CABG) surgery and is associated with significant morbidity and mortality. We investigated the..

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Modeling acid-base balance for in-series extracorporeal carbon dioxide removal and continuous venovenous hemofiltration devices

Abstract Patients with acute respiratory distress syndrome and acute kidney injury (AKI) treated by kidney replacement therapy may also require treatment with extracorporeal carbon dioxide removal (ECCO2R) devices to permit..

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To RAP or Not to RAP: A Retrospective Comparison of the Effects of Retrograde Autologous Priming

Abstract Retrograde autologous priming (RAP) is a process used to reduce hemodilution associated with the initiation of cardiopulmonary bypass (CPB). Previous studies have reported potential benefits to RAP; however, many..

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‘Goal-directed extracorporeal circulation: transferring the knowledge and experience from daily cardiac surgery to extracorporeal membrane oxygenation’

Abstract Metabolism management plays an essential role in extracorporeal technologies. There are different metabolic management devices integrated to extracorporeal devices; the most commonly used and accepted metabolic target in adult..

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Impact of partial pressure of oxygen trajectories on the incidence of acute kidney injury in patients undergoing cardiopulmonary bypass

Abstract Background To investigate the impact of the dynamic oxygenation status on the incidence of acute kidney injury (AKI) in patients undergoing cardiopulmonary bypass. Methods This retrospective study was performed..

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Gelatin and the risk of acute kidney injury after cardiac surgery

Abstract Background Gelatin has been used as a plasma volume expander because of its ability to preserve intravascular volume more effectively than crystalloids. However, gelatin may have detrimental effects on..

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Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury

Abstract Background Erythrocyte transfusions are independently associated with acute kidney injury. Kidney injury may be consequent to the progressive hematologic changes that develop during storage. This study therefore tested the..

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The Role of Race on Acute Kidney Injury Following Cardiac Surgery

Abstract Background Acute kidney injury (AKI) frequently complicates cardiac surgery and is more common among Black patients. We evaluated determinants of race-based differences in AKI rates. Methods Serum creatinine-based criteria..

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