Pediatric

Perfusfind S.L.

Abstract Objective: Mesenchymal stromal cells have important immunomodulatory and neuroprotective properties. The aim of this study was to evaluate the feasibility of mesenchymal stromal cell administration into a cardiopulmonary bypass (CPB) circuit, including a pediatric oxygenator, and to assess the immunomodulatory response of the circulating blood prime. Methods: A bypass..

Perfusfind S.L.

Abstract Background Cardiomyopathies in advanced stages and highly complex congenital heart disease may not be amenable to therapy or surgical correction thus being indicated pediatric heart transplant. In this study, we sought to report and evaluate the immediate and long-term outcomes of our 20 years experience in pediatric heart transplant...

Perfusfind S.L.

Abstract Objective To examine the altitude differences in the optimal perfusate oxygenation (PpO2) in patients who underwent cardiac surgery. Methods We included children (aged 1 month to 18 years) with  surgically repaired between 2012 and 2018. We included only patients who underwent cardiac surgery with arrested heart . Primary outcome was severe  (SIRS).  was used to..

Perfusfind S.L.

This case reports on a 10-year-old female (37 kg), who was admitted to the inpatient pediatric department with syncope with subsequent persistent somnolence and suspected intoxication. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/05/CoW_19_2021_E_web_compressed.pdf"]  

Perfusfind S.L.

Abstract Efforts to reduce the trauma and discomfort associated with thoracic and cardiac procedures in children have a long and complex history. While much of the early focus has been on smaller incisions, efforts to reduce the adverse effects of cardiopulmonary bypass, reduce pain associated with the incisions, and more..

Perfusfind S.L.

Abstract Donor shortage is a major limitation in organ transplantation. Several studies have reported that extracorporeal membrane oxygenation (ECMO)-assisted organ donation can be successfully completed without inducing warm ischemia in patients with brain death. The present report described clinical experience of three patients (23-yr old man, 32-yr old man, and..

Perfusfind S.L.

Abstract Background Little is known regarding the effect of cardiopulmonary bypass (CPB) reoxygenation on cardiac function following tetralogy of Fallot repair. We hypothesized that hyperoxic reoxygenation would be more strongly associated with myocardial dysfunction in children with tetralogy of Fallot. Methods We investigated the association of perfusate oxygenation (PpO2) associated..

Perfusfind S.L.

Abstract The coronavirus disease 2019 (COVID-19) pandemic has impacted people of all ages. Although children have been largely spared from the direct impact of the pandemic and only a minority of children affected with SARS-CoV-2 infection or the associated hyper-inflammatory syndrome require admission to a paediatric intensive care unit (PICU)..

Perfusfind S.L.

Abstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external artificial circuit carries venous blood from the patient to a gas exchange device (oxygenator) within which blood becomes enriched with..

Perfusfind S.L.

Abstract Low cardiac output syndrome and the systemic inflammatory response are consequences of the cardiac surgical perioperative course. The mechanisms responsible are multifactorial, but recent studies have shown that nitric oxide (NO) may be a key component in mitigating some of these processes. Following on from literature reports detailing the..