Pediatric

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Causes of red blood cell loss during extracorporeal membrane oxygenation

Abstract Background Pediatric patients on extracorporeal membrane oxygenation (ECMO) often receive repeated red blood cell (RBC) transfusions. This study aims to quantify and characterize causes of RBC loss on ECMO. Methods This retrospective, single-center, observational study includes 91 ECMO patients (age 1 day–20 years). An RBC loss index (RLI), equal to ml..

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Executive Summary of the Second International Guidelines for the Diagnosis…

Abstract OBJECTIVES:  We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS), considering new evidence and topic areas that were not previously addressed. DESIGN:  International consensus conference series involving 52..

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Extracorporeal Membrane Oxygenation in Pediatric Acute Respiratory Distress Syndrome: From…

Abstract OBJECTIVES:  To systematically review and assimilate literature on children receiving extracorporeal membrane oxygenation (ECMO) support in pediatric acute respiratory distress syndrome (PARDS) with the goal of developing an update to the Pediatric Acute Lung Injury Consensus Conference recommendations and statements about clinical practice and research. DATA SOURCES:  Electronic searches of MEDLINE..

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Variation in electroencephalography and neuroimaging for children receiving extracorporeal membrane…

Abstract Background Seizures, strokes, and intracranial hemorrhage are common and feared complications in children receiving extracorporeal membrane oxygenation (ECMO) support. Researchers and clinicians have proposed and deployed methods for monitoring and detecting neurologic injury, but best practices are unknown. We sought to characterize clinicians’ approach to electroencephalography (EEG) and brain..

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The characteristics of blood transfusion and analysis of preoperative factors…

Abstract Purpose Blood transfusion is a common and life-saving procedure in congenital heart surgery (CHS), and it is critical for patients to identify risk factors prior to surgery. Our objective is to conduct an analysis of the preoperative factors that influence blood use during CHS and to offer guidance on..

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After the storm: Extracorporeal membrane oxygenation after hemicraniectomy in a…

Abstract Ventricular arrhythmias following neurological injury have been attributed to sympathetic surge in subarachnoid hemorrhage and traumatic brain injury. Despite associated risks of bleeding and thrombosis, veno-arterial extracorporeal membrane oxygenation (ECMO) in critically ill, clinically unstable postoperative neurosurgical patients can be lifesaving. In the context of neurological injury and the..

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Predictors of Mediastinal Exploration While on Extracorporeal Membrane Oxygenation After…

Abstract Cardiac surgical patients requiring extracorporeal membrane oxygenation (ECMO) are at increased risk for hemorrhage due to necessary anticoagulation, in-situ cannulas, and disturbed hemostasis. We performed a retrospective, cross-sectional study of patients 0–18 years old in our cardiac intensive care unit (CICU) cannulated to ECMO within 48 h of cardiopulmonary bypass...

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Fluid Accumulation After Neonatal Congenital Cardiac Operation: Clinical Implications and…

Abstract Background This study was conducted to determine the association between fluid balance metrics and mortality and other postoperative outcomes after neonatal cardiac operation in a contemporary multicenter cohort. Methods This was an observational cohort study across 22 hospitals in neonates (≤30 days) undergoing cardiac operation. We explored overall percentage..

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Hemostatic Complications During Neonatal Extracorporeal Membrane Oxygenation: Roller Pump and…

Abstract Recently three different neonatal extracorporeal membrane oxygenation (ECMO) circuits have been employed in our clinic. These circuits were compared for clotting and bleeding complications. Initially, we used an ECMO circuit containing a roller pump and venous bladder without severe complications. Manufacturing of circuit components was discontinued, necessitating the replacement..

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Extracorporeal Membrane Oxygenation Cannulation Timing in the Pediatric Myocarditis Population:…

Abstract OBJECTIVES:  Children presenting with acute myocarditis may experience rapid clinical deterioration requiring extracorporeal membrane oxygenation (ECMO); however, our understanding of best practices and timing of ECMO initiation are lacking. We explored the relationships between pre-cannulation factors and survival in this high-acuity patient population. DESIGN:  Retrospective review of a large..

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