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Predictors of Neurologic Complications and Neurodevelopmental Outcome in Pediatric Cardiac Surgery With Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) has emerged as an important intervention for children both preceding and following cardiac surgery. There is a notable lack of comprehensive information regarding neurodevelopmental outcomes...

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VA-ECMO as a Bridge to Recovery in Refractory Circulatory Failure due to Bupropion Overdose

Abstract We present a case of successfully treating an adult woman with a lethal bupropion overdose with VA-ECMO. The patient presented to the hospital with severe encephalopathy, which progressed to..

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Using machine learning to predict neurologic injury in venovenous extracorporeal membrane oxygenation recipients: An ELSO Registry analysis

Abstract Background Venovenous extracorporeal membrane oxygenation (VV-ECMO) is associated with acute brain injury (ABI), including central nervous system (CNS) ischemia (defined as ischemic stroke or hypoxic-ischemic brain injury [HIBI]) and..

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Occurrence of Low Cardiac Index During Normotensive Periods in Cardiac Surgery: A Prospective Cohort Study Using Continuous Noninvasive Cardiac Output…

Abstract BACKGROUND:  Continuous cardiac output monitoring is not standard practice during cardiac surgery, even though patients are at substantial risk for systemic hypoperfusion. Thus, the frequency of low cardiac output..

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Association Between Persistent Hypothermia After Cardiopulmonary Bypass in Neonates and Odds of Serious Complications

Abstract IMPORTANCE:  Persistent hypothermia after cardiopulmonary bypass (CPB) in neonates with congenital heart defects (CHD) has been historically considered benign despite lack of evidence on its prognostic significance. OBJECTIVES:  Examine..

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Unraveling the Blood Biomaterial Interaction During Extracorporeal Membrane Oxygenation

Abstract Pediatric extracorporeal membrane oxygenation (ECMO) provides lifesaving cardiopulmonary support for patients with a multitude of clinical diagnoses, resulting from cardiac and/or respiratory failure refractory to conventional supports. The utilization..

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Effect of mannitol on postoperative delirium in patients undergoing coronary artery bypass graft: a randomised controlled trial

Abstract Objective Postoperative delirium (POD), especially after cardiac surgery with cardiopulmonary bypass (CPB), is a relatively common and severe complication increasing side effects, length of hospital stay, mortality and healthcare resource..

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A unique technique for thoracoabdominal aortic repair for 10 years: Normothermic iliac perfusion

Abstract Background The modality of thoracoabdominal aortic repair (TAAR) is mainly based on left heart bypass (LHB) in western countries, while in our team, it is mainly based on a..

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Alpha-Gal Syndrome and Cardiac Surgery

Abstract Galactose-alpha-1,3-galactose (alpha-gal) is a carbohydrate expressed by all mammals except for humans and certain old-world primates. It can be found in a plethora of products derived from mammals, including..

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Cerebral Oxygen Saturation Associates with Changes in Oxygen Transport Parameters during Cardiopulmonary Bypass

Abstract Background: Adequate organ perfusion during cardiopulmonary bypass (CPB) requires accurate estimation and adjustment of flow rates which conventional methods may not always achieve. Perioperative monitoring of cerebral oxygen saturation..

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A novel multimodal, intraoperative cognitive workload assessment of cardiac surgery team members

Abstract Objective To characterize cognitive workload (CWL) of cardiac surgery team members in a real-world setting during coronary artery bypass grafting (CABG) surgery using providers’ heart rate variability (HRV) data..

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Kinetics of Renin Concentrations in Infants Undergoing Congenital Cardiac Surgery

Abstract Background Elevated renin has been shown to predict poor response to standard vasoactive therapies and is associated with poor outcomes in adults. Similarly, elevated renin was associated with mortality..

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Is Cardiac Surgery Safe During Pregnancy? A 40-Year Single-Institution Experience

Abstract Background Limited data exist to characterize maternal and fetal outcomes during pregnancy undergoing cardiac operations using cardiopulmonary bypass. Methods A retrospective review was performed of all pregnant individuals who..

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A case of anaphylactic shock to human fibrinogen infusion during cardiac surgery

Abstract Human fibrinogen (FIB) has been clinically proven to be considerably effective for the treatment of postoperative bleeding, with reported cases of allergic reactions to human FIB being rare. Here,..

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ENDOTHELIAL-DEPENDENT VASCULAR REACTIVITY AFTER CARDIOPULMONARY BYPASS IS ASSOCIATED WITH UNIQUE METABOLOMIC SIGNATURES

Abstract Cardiopulmonary bypass (CPB), an extracorporeal method necessary for the surgical correction of complex congenital heart defects, incites significant inflammation that affects vascular function. These changes are associated with alterations..

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The evolving role of the modern perfusionist: Insights from processed electro-encephalography

Abstract Introduction: Since its origin in the 1920s, electroencephalography (EEG) has become a viable option for anesthesia and perfusion teams to monitor anesthetic delivery, optimizing drug dosage and enhancing patient safety...

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Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

Abstract When native blood flow through the aorta from the adult heart and lungs meets retrograde blood flow from an artificial heart and lung during venoarterial extracorporeal membrane oxygenation (VA-ECMO),..

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Aortic Root Replacement

Novel Technique for Aortic Root Replacement Art and Science of combination of Homograft Root Replacement with Cabrol interposition Tubular Graft for Coronary Ostia Reimplantation.  Dr.Sam Zeraatian Nejad Davani, CEO of..

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Geospatial Analysis for Prehospital Extracorporeal Cardiopulmonary Resuscitation in Houston, Texas

Abstract Objectives Extracorporeal cardiopulmonary resuscitation (eCPR) is a promising treatment that could improve survival for refractory out-of-hospital (OHCA) patients. Healthcare systems may choose to start eCPR in the prehospital setting..

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Factors Influencing Successful Weaning From Venoarterial Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract With advancements in  (ECLS) technologies, venoarterial  (VA-ECMO) has emerged as a crucial cardiopulmonary support mechanism. This review explores the significance of VA-ECMO system configuration,  strategies, and timing of initiation. Through an analysis..

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High Risk ECMO Cannula to Circuit Connection

Abstract A patient with a percutaneously inserted cardiopulmonary bypass cannula into the right internal jugular vein, connected to an extracorporeal membrane oxygenation (ECMO) circuit using tape, was referred for transport..

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Extracorporeal membrane oxygenation support in adult patients: Comparing COVID-19- and non-COVID-19-associated respiratory failure

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a vital intervention for acute respiratory distress syndrome (ARDS), yet its efficacy with coronavirus disease 2019 (COVID-19) remains unknown. This study compared the..

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The global blood donation index: an imperfect measure of transfusion need

Abstract The optimum number of units of blood and the associated number of blood donors required to meet a given population's needs remain undetermined globally. Typically, a whole blood donation..

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Hitting the (bio)mark part 1: selecting and measuring biomarkers in cardiovascular research

Abstract Cardiovascular studies, including nursing research, frequently integrate biomarkers for diagnostic, prognostic, monitoring, and therapeutic insights. However, effective utilization of biomarker data demands careful consideration. In the study design phase,..

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Reducing the prime cardiopulmonary bypass volume during paediatric cardiac surgery

Abstract Introduction Despite technological advances, the use of homologous blood to prime the cardiopulmonary bypass (CPB) circuits of infants under 10 kg remains common. However, such rapid massive transfusion may increase..

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Post-discharge health-related quality of life, cognitive function, disability, risk of post-traumatic stress disorder, and depression amongst the survivors of veno-venous…

Abstract Background Veno-venous extra-corporeal membrane oxygenation (VV-ECMO) is a form of mechanical respiratory support for critically ill patients with severe acute respiratory distress syndrome (ARDS). Using a large intravenous line in..

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Ultra-Low-Field Portable MRI and Extracorporeal Membrane Oxygenation: Preclinical Safety Testing

Abstract CONTEXT:  Conventional MRI is incompatible with extracorporeal membrane oxygenation (ECMO) cannulas and pumps. Ultra-low-field portable MRI (ULF-pMRI) with 0.064 Tesla may provide a solution, but its safety and compatibility..

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Implementation of a novel retrograde implantation technique for distal limb perfusion during extracorporeal cardiopulmonary resuscitation

Abstract In recent decades, the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has increased. In acute cardiogenic shock, VA-ECMO implantation can serve as a bridging solution to facilitate recovery, provide..

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Preoperative prophylactic insertion of intraaortic balloon pumps in critically ill patients undergoing coronary artery bypass surgery: a meta-analysis of RCTS

Abstract Background The intra-aortic balloon pump (IABP) technique plays a crucial role in providing circulatory support for patients experiencing hemodynamic instability. This study aimed to assess the effectiveness and safety..

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