Abstract Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) carries substantial transfusion requirements, exposing patients to increased risks of complications during hospital stay. This study evaluates the clinical impact of..
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Abstract The recent article by Ko et al., entitled “The effects of extracorporeal blood purification (oXiris®) in patients with cardiogenic shock who require VA-ECMO (CLEAN ECMO): a prospective, open-label, randomized..
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Abstract Objectives Targeted temperature management (TTM) is the standard of care for comatose cardiac arrest survivors. However, evidence regarding its long-term neurological impact specifically on in-hospital cardiac arrest (IHCA) survivors..
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Abstract Objectives To evaluate whether prolonged exposure below a Patient State Index (PSI) threshold of 25—considered indicative of excessive anesthesia depth via processed electroencephalography—is associated with postoperative delirium (POD) in..
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Abstract Objective To evaluate whether neighborhood-level opportunity, measured by the Child Opportunity Index (COI), is associated with short- and long-term outcomes following pediatric extracorporeal membrane oxygenation (ECMO). Design Retrospective observational..
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Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a type of mechanical circulatory support that is increasingly utilised for severe cardiorespiratory failure in the intensive care unit (ICU) setting. ECMO is..
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Abstract Background There is no universally accepted definition of perioperative blood loss in cardiac surgery. Existing methods are based on chest tube output and are not normalised for patient weight...
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Abstract Open thoracoabdominal aortic aneurysm repair (TAAAR) is associated with mortality rates of between 8% and 25%. One of the characteristics of TAAAR is massive bleeding that requires multiple units..
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Abstract Heparin-induced thrombocytopenia (HIT) in patients on mechanical circulatory support (MCS) prior to lung transplantation poses a unique challenge of balancing thrombotic versus hemorrhagic complications. An alternative method of anticoagulation..
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Abstract The applications of artificial intelligence (AI) in perioperative cardiothoracic and vascular practice continue to grow, given its multiple applications from discovery across translation and integration to delivery of clinical..
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Abstract Delirium remains a common yet important complication after coronary artery bypass grafting (CABG)., Despite robust research linking delirium to adverse outcomes in this setting, it is still regarded as a..
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Abstract Background Pediatric patients with combined irreversible pulmonary disease and right ventricular (RV) failure on conventional ECMO face significant challenges with rehabilitation and transplant candidacy. We describe our institutional experience..
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Abstract Background Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and..
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Abstract Extracorporeal life support, such as hemodialysis, often face the risk of blood coagulation, where systemic anticoagulation with heparin is routinely administered. However, this strategy is contraindicated in patients at..
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Abstract The global burden of cardiovascular diseases (CVDs) in adults is increasing. Over the past several decades, CVDs have remained the leading cause of death worldwide. Among CVDs, most mortality..
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Abstract Background Temperature variations during (CPB) may significantly contribute to the development and progression of (AKI) after cardiac surgery. We tested the hypothesis that temperature time-series variables during CPB are associated with..
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Abstract Neurally Adjusted Ventilatory Assist (NAVA) is an innovative mode of ventilation that delivers support in synchrony with the infant’s diaphragmatic electrical activity. This technology aims to improve patient–ventilator interaction,..
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Abstract Factor XII (FXII) is a central mediator at the intersection of coagulation, fibrinolysis, inflammation, and immunity. It is activated upon contact with negatively charged surfaces, triggering the intrinsic coagulation..
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Abstract Anaemia is the term for low red blood cell numbers or a deficiency of hemoglobin, the protein that carries oxygen in red blood cells. This results in a reduction..
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Abstract Myocardial injury is a major predictor of adverse cardiovascular outcomes and is driven by both ischemic and inflammatory mechanisms. Hyperbaric oxygen therapy (HBOT), which delivers 100% oxygen at supra-atmospheric..
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Abstract Objectives Neonates and infants who receive a Ross or Ross-Konno operation form a different population from older children and adults who undergo this procedure. We aimed to provide a..
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Abstract Objective To assess how inclusion criteria from major randomized controlled trials (RCTs) of extracorporeal cardiopulmonary resuscitation (ECPR) apply within a cannulated ECPR cohort and to benchmark observed outcomes against..
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Abstract Extracorporeal membrane oxygenation (ECMO) can trigger a systemic inflammatory response syndrome (SIRS) with activation of inflammatory, endothelial, and coagulation system pathways. We assessed in a randomized trial whether a)..
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Abstract Clinically, the inflammation induced by cardiopulmonary bypass (CPB) is associated with a higher incidence of severe complications and mortality. Based on the absorptive property of hemoperfusion, it has been..
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Abstract Background: Perioperative hyperglycemia is associated with adverse patient outcomes including surgical site infections. This study examined whether an automated insulin dosing reminder is associated with a lower risk for..
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Abstract BACKGROUND: Weaning from cardiopulmonary bypass (CPB) is a critical step in cardiovascular surgery. Although ionized calcium (iCa) plays a crucial role in myocardial contractility, and hypocalcemia commonly occurs during..
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Abstract Background: The clinical differences between intra-aortic balloon pumping (IABP) and a microaxial flow pump (Impella) for left ventricular (LV) unloading in patients with fulminant myocarditis (FM) supported with venoarterial extracorporeal..
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Abstract Background: Heparin is the standard anticoagulant used during cardiopulmonary bypass (CPB). However, there are problems with heparin, including immunogenicity and variability of effect, that make a search for an..
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Abstract Introduction Extracorporeal membrane oxygenation (ECMO) has been used in the care of critically ill neonates since the 1970s. Some neonatal ECMO indications include inadequate tissue oxygen delivery, severe hypoxic..
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Abstract Background: Lactic alkalosis, defined as an increase in circulating lactate in the setting of elevated extracellular pH, has been described in both in vivo and in vitro settings, often..
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