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End-of-Life in Extracorporeal Membrane Oxygenation (ECMO) Patients from an Islamic Perspective

Abstract Examining end-of-life care considerations within an Islamic context, the discussion delves into the intricate nuances surrounding ECMO patients. Drawing from Quranic teachings and Hadith principles, it underscores the sanctity..

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The art of aortic valve repair

Abstract In cardiac surgery, as with many endeavors, there is a point to which science can take you, and then art—namely observation, hands-on skill, craft, imagination, and mental imputation—must take..

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Rethinking ARDS classification: oxygenation impairment fails to predict VILI risk

Abstract Purpose: The selection and intensity of respiratory support for ARDS are guided by PaO 2/FiO2 . However, ventilator-induced lung injury (VILI) is linked to respiratory mechanics and ventilator settings...

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WARM BLOOD CARDIOPLEGIA VERSUS COLD CRYSTALLOID CARDIOPLEGIA IN PATIENTS AFFECTED BY ACUTE CORONARY SYNDROMES UNDERGOING CORONARY ARTERY BYPASS GRAFTING

Abstract Aim:  We investigated in a single-center retrospective study early outcomes of intermittent warm blood and cold crystalloid St. Thomas cardioplegia in patients referred to CABG due to acute coronary..

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Left Ventricular Energetics in Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation for Extracorporeal Cardiopulmonary Resuscitation

Abstract Introduction The haemodynamic effects veno-arterial extracorporeal membrane oxygenation (VA-ECMO) remain inadequately understood. We investigated invasive left ventricular (LV) haemodynamics in patients who underwent treatment with an intensive care strategy..

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Mechanical Circulatory Support for Massive Pulmonary Embolism

Abstract Up to 50% of patients with pulmonary embolism (PE) experience hemodynamic instability and approximately 70% of patients who die of PE experience an accelerated cascade of symptoms within the..

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Gattinoni’s Legacy: Personalizing ARDS Management Through Physiology

Abstract While writing this editorial, we learned that Professor Luciano Gattinoni—a giant in our field—had passed away. “Giant” seems an inadequate descriptor for a physician-scientist whose profound insights have fundamentally..

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Long-term heart function in refractory out-of-hospital cardiac arrest treated with prehospital extracorporeal cardiopulmonary resuscitation

Abstract Introduction Extracorporeal cardiopulmonary resuscitation (ECPR) is a treatment for refractory out-of-hospital cardiac arrest (OHCA), often due to acute coronary syndrome (ACS). However, the long-term impact of prehospital ECPR on..

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Perioperative blood pressure variability as a risk factor for postoperative delirium in the patients receiving cardiac surgery

Abstract Background Delirium is one of the most common neurological complications after cardiac surgery. The purpose of our study was to assess the relationship between perioperative blood pressure variability (BPV)..

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Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation

Abstract Open-lung ventilation during cardiopulmonary bypass (CPB) in patients undergoing heart transplantation (HTx) is a potential strategy to mitigate postoperative acute respiratory distress syndrome (ARDS). We utilized an ovine HTx..

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Assessment of Perioperative Protamine Reactions in Patients With Fish Allergies: A Retrospective Observational Study

Abstract Objectives To retrospectively assess the incidence and severity of perioperative protamine reactions in adult patients with documented history of fish allergy. Design Retrospective observational study. Setting Large academic tertiary..

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Acute kidney disease and postoperative glycemia variability in patients undergoing cardiac surgery: A multicenter cohort analysis of 8,090 patients

Abstract Background No previous research has specifically investigated the relationship between postoperative glycemic variability (GV) and acute kidney disease (AKD) in patients undergoing cardiac surgery. In this study, several methods..

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Optimizing Myocardial Protection in Minimally Invasive Cardiac Surgeries: A Network Comparison of Del Nido, Histidine-Tryptophan-Ketoglutarate, and Blood Cardioplegia

Abstract Background/Objectives: The optimal choice of cardioplegia solution in minimally invasive cardiac surgeries (MICS) remains debated, as prolonged myocardial protection is essential to avoid interruptions to the surgical flow, which..

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Prolonged Extracorporeal Circulation Leads to Inflammation and Higher Expression of Mediators of Vascular Permeability Through Activation of STAT3 Signaling Pathway…

Abstract Congenital heart defects (CHDs) are one of the most common congenital malformations and often require heart surgery with cardiopulmonary bypass (CPB). Children undergoing cardiac surgery with CPB are especially..

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Hyperlactataemia Following Crystalloid Cardiopulmonary Bypass Priming in Paediatric Cardiac Surgery—Benign or Malignant? A Retrospective Study

Abstract Background: Various mechanisms leading to early hyperlactataemia post-cardiac surgery have been postulated. Specifically, in the paediatric population, benign early hyperlactataemia may be associated with crystalloid priming in the cardiopulmonary..

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Differences in Plasma Extracellular Vesicles of Different Origin in On-Pump Versus Off-Pump Cardiac Surgery

Abstract Coronary artery bypass grafting (CABG) using cardiopulmonary bypass (CPB) causes a systemic inflammatory response that can worsen patient outcomes. Off-pump surgery has been associated with a reduced inflammatory response...

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Oxygen Delivery During Cardiopulmonary Bypass in Pediatric Patients With Congenital Heart Disease: Association With Postoperative Acute Kidney Injury

Abstract Objective This study was designed to investigate the distribution of nadir oxygen delivery (DO2), mean DO2, and area under ideal DO2 (AUiDO2) among categorized age groups of pediatric patients and..

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Association between plasma-free haemoglobin and postoperative acute kidney injury in paediatric cardiac surgery: a prospective observational study

Abstract Background Acute kidney injury (AKI) is a common complication among patients requiring cardiopulmonary bypass (CPB) during paediatric cardiac surgery. Plasma-free haemoglobin (PFH) produced by haemolysis during CPB contributes to..

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Association between iron metabolism and acute kidney injury in cardiac surgery with cardiopulmonary bypass: a retrospective analysis from two datasets

Abstract Objective We sought to explore the linear or nonlinear relationship between preoperative iron metabolism and acute kidney injury following cardiac surgery (CSA-AKI) with cardiopulmonary bypass (CPB). Methods Patients who..

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Efficacy of Therapeutic Plasma Exchange or Cangrelor as an Adjunctive Strategy to Facilitate Cardiopulmonary Bypass in Patients with Heparin-Induced Thrombocytopenia:…

Abstract Objective Conduct a systematic review and meta-analysis of the efficacy of therapeutic plasma exchange (TPE) or intravenous cangrelor to prevent thromboembolism in patients with heparin-induced thrombocytopenia (HIT) who undergo..

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Dose-Dependent Relationship between Iron Metabolism and Perioperative Myocardial Injury in Cardiac Surgery with Cardiopulmonary Bypass: A Retrospective Analysis

Abstract Introduction: We sought to comprehensively explore the potential linear and nonlinear relationship between preoperative iron metabolism and perioperative myocardial injury (PMI) following cardiac surgery with cardiopulmonary bypass (CPB).    Methods: Patients..

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Implementing a Labor and Delivery Cell Salvage Protocol in Patients at Increased Risk of Hemorrhage: A Pilot Study

Abstract Background: Postpartum hemorrhage (PPH) contributes significantly to maternal morbidity and mortality. The use of cell salvage has been implemented in operating rooms across the world, but only a limited..

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del Nido versus blood cardioplegia in cardiac surgery: A multicenter analysis of over 40,000 patients

Abstract Objectives The use of del Nido  in adult cardiac surgery is rising in popularity. The objective of this large multicenter study was to evaluate the use and associated outcomes of..

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Recommendations for fast-track extubation in adult cardiac surgery patients: a consensus statement

Abstract INTRODUCTION: Enhanced recovery after cardiac surgery in selected low-risk patients, has the potential to improve outcomes and reduce the burden of healthcare costs. Anesthesia-related challenges play a major role..

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Major Bleeding and Mortality After Revascularization of Left Main Disease

Abstract Background The incidence and prognostic impact of major bleeding (MB) after percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for left main coronary artery disease (LMCAD) are..

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Perioperative practitioners’ experiences of critical incident debriefing: A qualitative explorative study

Abstract Background: A critical incident is described as any unplanned event which causes, or has the potential to cause, injury to a patient. Critical incident debriefing is a team discussion..

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Cerebral Overperfusion Despite Reduced Cortical Metabolism Is Associated with Postoperative Delirium in Cardiac Surgery Patients: A Prospective Observational Study

Abstract Background: Decreased cerebral oximetry (rSO2) in cardiac surgery is associated with postoperative delirium (POD). However, interventions optimizing intraoperative rSO2 are inconclusive.    Methods: In this prospective observational cohort study, the..

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The 10 Commandments for Valve-Sparing Aortic Root Replacement

Abstract Valve-sparing root replacement (VSRR) has been performed for more than 30 years, both electively and in emergencies, with excellent long-term clinical outcomes. There are 2 main types of VSRR:..

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Predictors and Causes of Intraoperative Conversion From Off-Pump to On-Pump Coronary Artery Bypass: A Retrospective Study

Abstract Objective: This study evaluated the incidence, causes, and predictors of intraoperative conversion from off-pump coronary artery bypass grafting (OPCAB) to on-pump coronary artery bypass grafting (ONCAB), identifying risk factors..

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Acute normovolemic haemodilution to reduce allogeneic red blood cell transfusion in patients undergoing coronary artery bypass grafting. An observational study

Abstract Background and Objective Patients undergoing cardiac surgery consume more than 50% of blood transfusions, and such transfusions have been associated with increased morbidity and mortality. Evidence in blood-saving techniques..

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