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A New Multifunction Oxygenator With a Dual-Chamber Gas Exchanger to Reduce Dependence on Oxygen Supply

Abstract Although extracorporeal membrane oxygenation (ECMO) systems have been used to provide temporary support for patients with severe respiratory or cardiac failure, they are often bedridden, in part because of..

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International Consensus on Evidence Gaps and Research Opportunities in Extracorporeal Cardiopulmonary Resuscitation for Refractory Out‐of‐Hospital Cardiac Arrest: A Report From…

Abstract The increased accessibility of extracorporeal membrane oxygenation following the COVID‐19 pandemic and the publication of the first randomized trial of extracorporeal cardiopulmonary resuscitation (ECPR) prompted the National Heart, Lung,..

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Normothermic Regional Perfusion in Controlled Donation After the Circulatory Determination of Death: Understanding Where the Benefit Lies

Abstract Controlled donation after the circulatory determination of death (cDCDD) has emerged as a strategy to increase the availability of organs for clinical use. Traditionally, organs from cDCDD donors have..

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Low- vs. Moderate-Intensity Anticoagulation for Venovenous Extracorporeal Membrane Oxygenation: The SAFE-ECMO Pilot Trial

Abstract Background Bleeding is a common and sometimes fatal complication of venovenous extracorporeal membrane oxygenation (ECMO). Whether lowering the intensity of anticoagulation during venovenous ECMO is safe or effective is..

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Anticoagulation in ECMO: Target Values to Reduce Hemorrhagic Complications in Adults. A Retrospective Cohort Study

Abstract The 2021 Adult and Pediatric Anticoagulation Guidelines for patients on extracorporeal membrane oxygenation (ECMO) recommend a target partial thromboplastin time (PTT) between 60 and 85 seconds when unfractionated heparin..

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Flow Physiology of Extracorporeal Circulation

Introduction Extracorporeal circulation (ECC), used in cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), serves as a temporary replacement for the heart and lungs. It maintains tissue perfusion and gas..

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Sedation and Hemodynamic Control During ECMO: The Perfusionist’s Role

Introduction Extracorporeal Membrane Oxygenation (ECMO) is a life-saving intervention for patients with severe cardiac and/or respiratory failure. Unlike cardiopulmonary bypass (CPB), ECMO can run for days to weeks, requiring meticulous..

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ECMO Physiology: Oxygen Content, Capacity, Delivery, and Consumption

Extracorporeal Membrane Oxygenation (ECMO) is a life-saving intervention for patients with severe cardiac or respiratory failure. A thorough understanding of ECMO physiology, particularly oxygen transport dynamics, is essential for optimizing..

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Pulsatile vs. Non-Pulsatile Cardiopulmonary Bypass: A Comparative Analysis

Introduction Cardiopulmonary bypass (CPB) has been the cornerstone of modern cardiac surgery, allowing for safe cardiac arrest while maintaining systemic perfusion. However, the debate between pulsatile and non-pulsatile flow during..

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Blood Conservation and Cardiopulmonary Bypass

Introduction Cardiopulmonary bypass (CPB) is a vital component of cardiac surgery, allowing surgeons to perform complex procedures on a still, bloodless heart. However, CPB is associated with significant hemodilution, coagulopathy,..

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Comparing unilateral and bilateral cerebral perfusion during total arch replacement for acute type A aortic dissection

Abstract OBJECTIVES To assess the effects of unilateral versus bilateral antegrade cerebral perfusion (u-ACP vs. b-ACP) on postoperative complications and mid-term follow-up results in Asian patients with acute type A..

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First-Day Platelet Count Is Associated With In-Hospital Mortality in Adult Postcardiotomy Extracorporeal Membrane Oxygenation

Abstract To investigate the relationship between platelet counts within the first 24 hours of veno-arterial extracorporeal membrane oxygenation (V-A ECMO) support and in-hospital mortality in postcardiotomy ECMO patients. Adult patients..

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Outcomes of type A aortic dissection in Australia

Abstract Introduction Without surgical intervention, type A aortic dissection (TAAD) carries a high risk of life-threatening complications and mortality. Due to the low incidence of aortic dissection, case numbers vary..

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Expert consensus on the use of human serum albumin in critically ill patients

Abstract Human serum albumin (HSA) is a non-glycosylated, negatively charged, single-chain polypeptide composed of 585 amino acid residues with a relative molecular mass of 66.438 kD. It is synthesized by..

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Comparison of Extracorporeal Membrane Oxygenation Initiation in Cardiogenic Shock During Work-Hours Versus After-Hours

Abstract Background Extracorporeal membrane oxygenation (ECMO) as rescue therapy for cardiogenic shock (CS) is highly dependent on timeliness and medical resources. Objectives Aimed to assess ECMO management and outcomes in..

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Benefit of minimally invasive extracorporeal circulation on minimally invasive aortic valve replacement through right lateral mini-thoracotomy using femoral cannulation: a…

Abstract OBJECTIVES The objective of this study was to evaluate the impact of minimally invasive extracorporeal circulation on blood transfusion and asymptomatic brain injury in comparison to conventional extracorporeal circulation..

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Neurodevelopmental Outcomes After Nitric Oxide During Cardiopulmonary Bypass for Open Heart Surgery

Abstract Importance  Children with congenital heart defects who undergo cardiopulmonary bypass (CPB) surgery are at risk for delayed or impaired neurodevelopmental outcomes. Nitric oxide (NO) added to the CPB oxygenator may..

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Monitoring of perioperative tissue perfusion and impact on patient outcomes

Abstract Monitoring perioperative tissue perfusion is crucial in clinical anesthesia to protect organs and ensure patient safety. Indicators like hemodynamic parameters, tissue metabolism, and microcirculation markers are used for assessment...

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Quality comparison of autotransfusion devices in cardiac surgery: a prospective observational cohort study

Abstract Purpose We sought to conduct a quality improvement initiative to compare the wash quality and speed of autologous red blood cell (RBC) processing of four autotransfusion devices during cardiac..

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Virtual 3D reconstruction of complex congenital cardiac anatomy from 3D rotational angiography

Abstract Background Despite advancements in imaging technologies, including CT scans and MRI, these modalities may still fail to capture intricate details of congenital heart defects accurately. Virtual 3D models have..

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Enhanced Hemodynamics of Anisometric TPMS Topology Reduce Blood Clotting in 3D Printed Blood Contactors

Abstract Artificial organs, such as extracorporeal membrane oxygenators, dialyzers, and hemoadsorber cartridges, face persistent challenges related to the flow distribution within the cartridge. This uneven flow distribution leads to clot..

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Renal macro- and microcirculatory perturbations in acute kidney injury and chronic kidney disease associated with heart failure and cardiac surgery

Abstract Chronic kidney disease (CKD) affects 50% of patients with heart failure. The pathophysiology of CKD in heart failure is proposed to be driven by macrocirculatory hemodynamic changes, including reduced..

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ECMO cannulation across New England

Abstract Background Over the last 15 years, clinicians have increasingly used extracorporeal membrane oxygenation (ECMO) as a rescue technique, including cannulating patients in community hospitals without ECMO capabilities, leading to..

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Does methylene blue improve outcomes in patients with post-cardiac surgery vasoplegic syndrome?

Abstract OBJECTIVES A best evidence topic was written according to a structured protocol described in ICVTS. The question addressed was ‘In patients with vasoplegic syndrome following cardiac surgery with cardiopulmonary bypass,..

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Variability in triggers for mechanical left ventricular unloading in VA-ECMO: A literature search

Abstract Background: Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) is a means of supporting the lungs or the heart and lungs in patients with hemodynamic compromise that is refractory to conventional measures...

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Impact of behavior change theory-based nursing interventions on cardiac function recovery and quality of life among cardiac surgery patients with…

Abstract Background This study investigates the impact of nursing interventions, guided by behavior change theory, on the recovery of cardiac function and quality of life in patients undergoing cardiac surgery..

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Urine biomarkers, acute kidney injury, and fluid overload in neonatal cardiac surgery

Abstract Background:Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus,..

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Intra- and early postoperative predictors of delirium risk in cardiac surgery: results from the prospective observational FINDERI study

Abstract Background:  Postoperative delirium (POD) is a severe complication following cardiac surgery and is associated with increased morbidity and mortality. The impact of intra- and early postoperative factors on the..

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A review of nomenclature in minimally invasive coronary artery bypass grafting—the anarchy of terminology

Abstract OBJECTIVES Since the development of minimally invasive coronary surgery, nomenclature has rapidly grown to distinguish each unique method. The goal of this review was to provide a comprehensive overview..

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Hemodynamics of Veno-Pulmonary Extracorporeal Membrane Oxygenation With Varying Right Ventricular Function in a Mock Circulatory Loop

Abstract Veno-pulmonary extracorporeal membrane oxygenation (VP ECMO) is an emerging mechanical support therapy for patients with right ventricular (RV) injury. This study aimed to assess the hemodynamic impact of VP..

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