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The role of mediastinal blood in the development of postoperative atrial fibrillation after cardiac surgery

Abstract Introduction Atrial fibrillation (AF) is the most common arrhythmia following cardiac surgery. Although many risk factors have been studied, none has emerged as a dominant and widely applicable prophylactic measure. Aim..

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Development of an Optical Sensor for Real-Time Monitoring of Hemodynamic Parameters in Extracorporeal Settings

Abstract Objective: Whole blood oxygen saturation and hemoglobin concentration are key markers of health across a variety of clinical contexts. Extracorporeal systems (dialysis, cardiopulmonary bypass, ECMO, etc.) require close monitoring..

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Central veno-arterial ECMO via an aortic prosthetic graft as significant alternative to peripheral ECMO cannulation: evaluation of patient outcomes in…

Abstract Background For patients presenting with cardiogenic shock due to acute myocardial ischaemia, veno-arterial extracorporeal membrane oxygenation (ECMO) is often the only potential lifesaving intervention remaining when revascularisation does not..

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Evaluating Topical Antifibrinolytics in Cardiac Surgery: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis

Abstract Introduction Lysine analog antifibrinolytics (LAAF) like tranexamic acid (TXA) and aminocaproic acid (EACA) reduce intraoperative blood loss, especially in cardiac surgery where bleeding risks are high. These LAAFs inhibit..

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Hartford Hospital Adult ECMO Training Course - May 11/13

Date & Location Monday, May 11, 2026, 7:00 AM - Wednesday, May 13, 2026, 4:30 PM ET, Heart & Vascular Insititute, CESI @ Hartford Hospital, Hartford, CT Registration This course is limited..

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DanGer Shock Symposium - June 5

5 June Auditorium 1 (Rigshospitalet, Copenhagen, DK) Christian Hassager (RH), Jacob Eifer Møller (RH, OUH)

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DCD step by Step for Heart and lung donation

      1. Donor Identification •Identify a potential DCD donor (Maastricht category III or II in some systems). •Patient has devastating neurologic or systemic injury but does not meet..

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Redo Bentall operation for right coronary artery (RCA)

A redo Bentall operation for right coronary artery (RCA) ostial insufficiency represents one of the most technically demanding scenarios in complex aortic root surgery. This condition typically arises from progressive..

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Robotic Right Upper Sleeve Lobectomy With Rotational Azygous Vein Flap

In this video, the authors demonstrate a robotic right upper sleeve lobectomy with a rotational azygos vein flap. The patient was a 68-year-old female presenting with a right supra-hilar non-small..

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Üsküdar Perfüzyon Kongresine - 1/3 Mayis

Değerli bilim insanları ve sektör profesyonelleri, 1 - 3 Mayıs 2026 tarihlerinde Üsküdar Üniversitesi ev sahipliğinde gerçekleştirilecek “4. ÜSKÜDAR PERFÜZYON KONGRESİ”ne sizleri davet etmekten mutluluk duyarız. Kongremiz; bütüncül bakış açısı..

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Arterial Versus Mixed Venous Lactate Levels in 1526 Cardiac Intensive Care Patients

Abstract Time is critical in the diagnosis and treatment of cardiogenic shock, even more so than in septic shock. Early identification enables prompt circulatory support and restoration of tissue oxygenation. Baseline..

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Normothermic Regional Perfusion in Controlled Donation After Circulatory Death: Growing Evidence for Liver Transplantation

Abstract Normothermic regional perfusion (NRP) has emerged as one of the most consequential innovations in modern liver transplantation, particularly in the context of controlled donation after circulatory death (cDCD). Historically,..

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Preoperative and Intraoperative Risk Factors for Postoperative Pneumonia After Cardiac Surgery: An Ancillary Study of the STERNOCAT (Catheter Outcomes With…

Abstract Objective:  Postoperative pneumonia (POP) is a frequent complication after cardiac surgery, which significantly worsens prognosis. This study aimed to identify preoperative and intraoperative factors independently associated with POP in..

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Evaluation of a Rat Cardiopulmonary Bypass Model Using an Extraluminal Flow Oxygenator

Abstract Background Cardiac operations with cardiopulmonary bypass (CPB) trigger a systemic inflammatory response. To understand the underlying mechanisms behind the biological reactions during CPB, rat models that mimic clinical CPB..

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Predictors and Economic Impact of Red Blood Cell Transfusion in Cardiac Surgery: A Simulated Cost Reduction Model for Preoperative Anemia…

Abstract Introduction: Red blood cell (RBC) transfusions are frequent in cardiac surgery and are associated with higher morbidity, mortality, prolonged hospitalization, and increased healthcare costs. Several patient- and procedure-related factors have..

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Association Between Intraoperative Hyperlactatemia and Infection After Cardiac Surgery With Cardiopulmonary Bypass: A Multicenter Retrospective Study

Abstract Objectives To test the hypotheses that intraoperative hyperlactatemia is independently associated with increased postoperative infection risk in cardiac surgery with cardiopulmonary bypass (CPB). Methods This study involved 4970 cardiac..

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Cellular and molecular signals of cardiac wound healing after myocardial infarction

Abstract Wound healing after myocardial infarction (MI) is a dynamic and multifaceted process that links the molecular alterations induced by or in response to prolonged ischemia with structural and physiological..

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Implementation of audiovisual recording in the operating room: a nationwide survey of stakeholder perspectives in France

Abstract Background Audiovisual recording technology, referred to as the Operating Room Black Box (ORBB), is increasingly adopted in operating rooms (ORs) across several countries. It is described as beneficial, with..

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Successful management of IgE-mediated protamine allergy in cardiac surgery: bicentric case report

Abstract Since the use of heparin reversed by protamine is the gold standard for anticoagulation during cardiopulmonary bypass (CPB), a documented allergy to protamine represents a serious challenge for cardiac..

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Combined Antithrombin and Heparin Supplementation to Blood for Restoring Heparin Responsiveness After Andexanet Alfa Exposure: An In Vitro Model

Abstract Background: Andexanet alfa, a Gla-domainless mutant factor Xa (GDXa), reverses oral FXa inhibitors but can cause severe heparin resistance during cardiopulmonary bypass (CPB). Antithrombin (AT) supplementation may mitigate this..

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Life-Threatening Iatrogenic Pulmonary Hemorrhage Managed with Salvage Anticoagulation-Free Venovenous Extracorporeal Membrane Oxygenation

Abstract SEVERE HEMOPTYSIS REMAINS A significant medical emergency, often requiring a multidisciplinary approach to identify the bleeding source and implement effective treatment. Airway obstruction due to clots secondary to massive..

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Antimicrobial stewardship during extracorporeal membrane oxygenation: challenges and new perspectives

Abstract Background Extracorporeal membrane oxygenation (ECMO) has emerged as a crucial modality in managing severe cardiac and respiratory failure; however, nosocomial infections and complex antimicrobial prescribing challenges may accompany its..

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Optimising protamine dosing for heparin reversal after cardiopulmonary bypass: a population pharmacokinetic–pharmacodynamic study

Abstract Background Protamine is administered to reverse unfractionated heparin (UFH) after cardiopulmonary bypass (CPB), but dosing strategies—typically based on protamine-to-heparin (P:H) ratios—vary, and the minimal effective dose remains unclear. Reversal..

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Diagnostic Pathways for Refractory Hypoxemia in ECMO: A Case-Based Troubleshooting Approach

Abstract Despite significant advancements in critical care practice and extracorporeal technology, refractory hypoxia remains a persistent clinical challenge during extracorporeal membrane oxygenation (ECMO). To demonstrate a systematic, algorithmic pathway for..

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Efficacy of Hemoadsorption in Cardiac Surgery with Cardiopulmonary Bypass: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Abstract Objectives To evaluate the efficacy of intraoperative hemoadsorption (HA) during cardiopulmonary bypass (CPB) in reducing acute kidney injury (AKI) and other major postoperative complications in patients undergoing cardiac surgery...

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Surgical management of growing teratoma syndrome requiring cardiopulmonary bypass and total superior vena cava resection and reconstruction

Abstract Background After chemotherapy, a small subset of mediastinal non-seminomatous germ cell tumors evolves into growing benign teratoma masses despite normalized tumor markers. This condition is termed the growing teratoma..

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Venoarterial Extracorporeal MembraneOxygenation in Septic Shock and/or Sepsis-induced Cardiomyopathy: A Systematic Review of Fifteen Studies

Abstract Objective(s) To evaluate survival outcomes and identify candidate profiles for venoarterial extracorporeal membrane oxygenation in adult patients with sepsis-induced cardiomyopathy. Design The authors systematically searched PubMed, Embase, and Google..

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Three Decades of Evidence on Pulsatile Cardiopulmonary Bypass in Pediatrics: No Significant Clinical Benefit

Abstract Background Drawing on more than 30 years of valuable expertise in in-vitro, in-vivo, and clinical trials, we report the key findings of our institutional research on pulsatile cardiopulmonary bypass..

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External Perfusion Centers Can Bridge the Gap of Experience During Ex Vivo Lung Perfusion: A United Network for Organ Sharing…

Abstract Previously, limited cumulative experience has been linked to poor transplantation outcomes following ex vivo lung perfusion (EVLP). We sought to determine if EVLP performed at external perfusion centers (EPC) could mitigate..

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