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Multidisciplinary, evidence-based, patient-centred perioperative patient safety recommendations: a European consensus study

Abstract Background Surgery-related adverse events are among the most common adverse events in-hospital. However, no comprehensive, multidisciplinary perioperative guidelines exist at the European level. The aim of this study is..

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Cycle ergometers in extracorporeal membrane oxygenation patient rehabilitation: A scoping review

Abstract Introduction The aim of this scoping review was to determine what evidence is available regarding the use of the cycle ergometer in the rehabilitation of adult patients undergoing extracorporeal..

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Circulating amino acid levels in infants undergoing congenital heart disease surgery: near global decrease following cardiopulmonary bypass and impact of…

Abstract Introduction Amino acids (AAs) serve diverse roles, and insufficient delivery is associated with worse outcomes in ill patients. In the case of congenital heart disease (CHD) surgery with cardiopulmonary..

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Human judgment error in the intensive care unit: a perspective on bias and noise

Abstract Background In the Intensive Care Unit (ICU), clinicians frequently make complex, high-stakes judgments, where inaccuracies can profoundly affect patient outcomes. This perspective examines human judgment error in ICU settings,..

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Near-Infrared Spectroscopy for Preventing Limb Ischemia in Extracorporeal Membrane Oxygenation

Abstract Background Limb ischemia is a serious complication of venoarterial (VA) extracorporeal membrane oxygenation (ECMO), potentially resulting in amputation, rhabdomyolysis, or death. This study aimed to evaluate the effectiveness of..

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Intravenous amino acids for renal protection in patients receiving temporary mechanical circulatory support: a secondary subgroup analysis of the PROTECTION…

Abstract OBJECTIVES In cardiac surgery patients, acute kidney injury (AKI) frequently occurs in the setting of haemodynamic instability and treatment with temporary mechanical circulatory support (tMCS). Recent evidence suggests amino..

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Total thyroidectomy performed under general anesthesia with venovenous extracorporeal membrane oxygenation during a thyroid storm: a case report

Abstract Thyroid storm (TS) is an endocrine emergency requiring aggressive medical management. In severe cases, hemodynamic instability may necessitate extracorporeal membrane oxygenation (ECMO) support as a bridge to definitive surgical..

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Additional Carbon Dioxide Removal by Oxygenated Dialysis Fluid: Insights for the Development of a Novel Lung and Kidney Assist Device

Abstract RenOx, a novel artificial lung and kidney assist device, combines gas exchange and dialysis fibers for integrated respiratory and renal support, with dialysis fibers intended for toxin clearance and..

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Redefining weaning in a VA ECMO: a case report on pump-controlled retrograde trial off

Abstract Extracorporeal membrane oxygenation (ECMO) is widely recognized as a life-saving measure. The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is on the rise, serving as an effective mechanical..

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The predictive power of hemodynamic data on postoperative neurocognitive impairment: a logistic regression and random forest approach

Abstract This study assesses hemodynamic data and parameter combinations in predicting neurocognitive impairment post-cardiopulmonary bypass graft (CABG) using logistic regression and random forest algorithms. 28 patients underwent the Montreal Cognitive..

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The Effect of Sevoflurane Versus Total Intravenous Anesthesia on Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery with…

Abstract Background and Objectives: The aim of this study was to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia (TIVA) on intraocular pressure (IOP) during coronary artery..

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Visualizing Flow Dynamics in a Human Aorta During Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Treatment Through Particle Image Velocimetry Study

Abstract Purpose To build a mock circulatory loop to simulate veno-arterial extracorporeal membrane oxygenation (V-A ECMO) haemodynamics using a patient-specific silicone aortic phantom and compare the flow dynamics for continuous..

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The Impact of the COVID-19 Pandemic on Intensive Care Nurses' Experience in Providing Extracorporeal Membrane Oxygenation Care

Abstract To explore the challenges and describe the impact of the COVID-19 pandemic on intensive care nurses' experience in providing ECMO care in a high-volume Australian ICU ECMO centre that..

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Heparin-free veno-venous ECMO for airway obstruction: A case report and review of literature

Abstract Rationale:  Life-threatening airway obstructions caused by tumors demand prompt and effective intervention. Traditional surgical methods are often complicated by bleeding risks, especially with the use of anticoagulation during extracorporeal..

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Direct procurement with machine perfusion and normothermic regional perfusion in donation after circulatory death heart transplantation

Abstract Background Donation after circulatory death (DCD) heart transplants have increased in the United States with direct procurement with machine perfusion (DPP) and thoracoabdominal normothermic regional perfusion (TA-NRP) techniques. There..

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Impact of Intraoperative Cell Salvage on Circulating Tumor Cells and Cellular Activity in Patients with Hepatocellular Carcinoma Undergoing Curative Resection:…

Abstract This study investigates the effects of intraoperative cell salvage (IOCS) on cell survival rates, apoptosis levels, and circulating tumor cell (CTC) counts in patients with hepatocellular carcinoma (HCC) undergoing..

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Rise of the machines: Normothermic regional perfusion use in heart transplantation in the United States

Abstract Background Normothermic regional perfusion (NRP) and direct procurement and perfusion (DPP) allow for transplantation with donation after circulatory death (DCD) hearts. This study aimed to characterize the use of..

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Machine Learning–Based First-Day Mortality Prediction for Venoarterial Extracorporeal Membrane Oxygenation: The Novel RESCUE-24 Score

Abstract Extracorporeal membrane oxygenation (ECMO) provides critical cardiac support, but predicting outcomes remains a challenge. We enrolled 1,748 adult venoarterial (VA)-ECMO patients at the National Taiwan University Hospital between 2010..

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Weight Categories Have no Impact on Mortality in Patients Treated with Extracorporeal Membrane Oxygenation (ECMO)

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) is a critical support system for patients with acute and severe cardiac and respiratory failure. This study investigates the impact of different patient body..

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Feasibility and effectiveness of the novel HemoClear microfiltration cell-salvage system in cesarean sections in South Africa

Abstract Objective To test the feasibility and effectiveness of implementing the HemoClear microfiltration cell-salvage system for cesarean sections in South Africa. Methods We conducted a prospective experimental single-arm feasibility study..

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The effects of extracorporeal blood purification (oXiris®) in patients with cardiogenic shock who require VA-ECMO (CLEAN ECMO): a prospective, open-label,…

Abstract Background A systemic inflammatory response can contribute to poor outcomes in an advanced stage of cardiogenic shock (CS). We investigated the efficacy of extracorporeal endotoxin and cytokine adsorption using..

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Evaluation of Intraoperative Bivalirudin Anticoagulation in Neonates and Infants Undergoing Arterial Switch Operation on Integrated ECMO-CPB Circuit: A Prospective Study

Abstract Objectives To ascertain the dosage of bivalirudin in neonates and infants undergoing arterial switch operation on integrated extracorporeal membrane oxygenation–cardiopulmonary bypass (CPB) circuit. Design Pilot study. Setting A tertiary..

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Use of Cell Saver in Elective Coronary Bypass Surgery: What Do We Risk When Saving Blood?

Abstract Background/Objectives: Allogeneic transfusion is a commonly used method to replace blood and blood elements lost during cardiac surgery, but it also has quite undesirable effects. The use of Cell Saver..

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Hyperlactatemia in Critically Ill Children: Modeling Early Recovery Kinetics After Initiation of Extracorporeal Membrane Oxygenation

Abstract Objectives:  Blood lactate concentration ([Lac]b) reflects the balance among production, clearance (Cl[Lac]), and volume of distribution. We have observed dramatic improvement in [Lac]b in critically ill patients after starting support..

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Checklist conundrum: are we checking the right boxes?

Abstract Since the 18th century, bedside rounds have been a fundamental component of clinical care, serving as a setting where clinical information is gathered, processed and shared. This tradition highlights the..

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Sickle Cell Disease and Cardiopulmonary Bypass: A Multidisciplinary Approach to High-Risk Cardiac Surgery

1. Introduction Sickle Cell Disease (SCD) is a chronic, inherited blood disorder resulting from a single point mutation in the β-globin gene. This mutation leads to the production of hemoglobin..

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Minimizing Cardiopulmonary Bypass Time: Are We Saving Lives or Just Minutes?

In modern cardiac surgery, cardiopulmonary bypass (CPB) plays a life-saving role. It allows the heart to be stopped safely while the body is perfused with oxygenated blood. However, it’s a..

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Pressure drop across common LV vent catheters

Abstract Purpose This study examined the pressure drop across several LV vent catheters commonly used in adult and pediatric cardiac surgery to identify optimal vent catheters for different flows that..

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Canonical flow structures formed in a diagonal pump used in extracorporeal membrane oxygenation

Abstract This study focuses on the fluid dynamics of a blood pump used in extracorporeal membrane oxygenation (ECMO). In ECMO, the patient's blood is pumped through a circuit composed of..

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Tailored preoperative assessment in neonatal cardiac surgery: a European Congenital Heart Surgeons Association study

Abstract OBJECTIVES Current preoperative counselling in neonatal cardiac surgery is mainly focused on the primary procedure. However, other factors must be considered when evaluating the surgical risk of a neonate...

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