Abstract Essentials Strategies to improve platelet function may reduce excessive bleeding during cardiac surgery. Patients were randomized to standard care or standard care + noradrenaline infusion. Low‐dose noradrenaline improved intraoperative..
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Abstract Perfusion strategies for have direct consequences on pediatric cardiac surgery outcomes. However, inconsistent study results and a lack of uniform evidence-based guidelines for pediatric cardiopulmonary bypass management have led to..
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Abstract Background During cold storage, some red blood cell (RBC) units age more rapidly than others. Yet, the Food and Drug Administration has set a uniform storage limit of 42..
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Abstract Background and Aim of the Study Extracorporeal life support (ECLS) may be necessary in refractory postcardiotomy cardiogenic shock (PCS) unresponsive to optimal medical treatment. We sought to analyze the..
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Abstract Central venoarterial extracorporeal membrane oxygenation has been used since the 1970s to support patients with cardiogenic shock following cardiac surgery. Despite this, in-hospital mortality is still high, and although..
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Abstract Objectives Our aim was to describe the pharmacokinetics of cefazolin in paediatric patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) who received cefazolin for peri-operative surgical prophylaxis in addition..
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Abstract Summary We investigated microcirculatory perfusion disturbances following cardiopulmonary bypass in the early postoperative period and whether the course of these disturbances mirrored restoration of endothelial glycocalyx integrity. We performed..
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Abstract Pediatric cardiac surgical patients are at particular risk for post-cardiopulmonary bypass hemorrhage. Moreover, both the incidence and volume of have been associated with increased morbidity in pediatric cardiac patients. Transfusion..
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Abstract Extracorporeal membrane oxygenation is a rapidly emerging treatment for respiratory or cardiac failure and is used as a bridge to recovery, transplant, or destination therapy. Adult patients receiving extracorporeal..
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Abstract Background The predictors and independent outcome association of after cardiac surgery are important and yet poorly characterised. Methods We performed a retrospective of cardiac surgery patients between January 2009 and March..
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Abstract Background: Administering isoflurane 2.5% into the oxygenator during cardiopulmonary bypass results in no patient movement. However, doing so may result in an excessive depth of anaesthesia particularly, when hypothermia..
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Abstract Legionella community–acquired pneumonia necessitating veno-venous extracorporeal membrane oxygenation for severe acute respiratory distress syndrome has been reported in adults. However, few options remain in cases of refractory hypoxemia on..
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Abstract Background Venoarterial (VA) (ECMO) application in postcardiotomy shock (PCS) and non-PCS is increasing. VA-ECMO plays a critical role in the management of these patients, yet may be associated with serious..
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Abstract Objective induces degradation of . The authors hypothesized that inflammation is an important determinant of glycocalyx degradation in patients undergoing cardiac surgery with (CPB). Design A prospective . Setting Operation theater and..
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Case 1 A 78-year-old male diabetic patient underwent elective coronary artery bypass grafting (CABG). His insulin therapy had been changed recently to human insulin (Humulin M3; Eli Lilly Italia, Sesto..
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Abstract Objectives To determine whether precardiopulmonary bypass (CPB) normalization of levels in infants to 100% improves heparin sensitivity and during CPB and has beneficial effects into the . Design Randomized, double-blinded, placebo-controlled prospective..
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Abstract Background Arginine vasopressin (AVP) is a naturally occurring peptide with diverse effects mediated through selective V1 and V2 receptors. About 10% of patients undergoing cardiopulmonary bypass develop postoperative vasodilatory..
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Abstract The objective of this study is to establish reliable markers for mortality in children with refractory cardiogenic shock who underwent extracorporeal membrane oxygenation. A retrospective observational cohort study was..
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Abstract Background Despite concern that cardiac surgery may adversely affect cognition, little evidence is available from population-based studies using presurgery data. With the use of the Health and Retirement Study,..
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OBJECTIVES Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence..
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Summary Thromboelastometry point‐of‐care coagulation testing facilitates optimised management of bleeding. Previous thromboelastometry systems required the blood sample and liquid reagents to be pipetted in several manual steps by trained personnel...
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Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis..
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Abstract Pump thrombosis and stroke are serious complications of left ventricular assist device (LVAD) support. The aim of this study was to test the ability of an accelerometer to detect..
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Abstract Systemic anticoagulation is a standard of care in adult patients supported by extracorporeal membrane oxygenation (ECMO) to prevent circuit thrombosis and subsequent thromboembolic events. Unfractionated heparin has long been..
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POSTOPERATIVE PULMONARY dysfunction, a known complication after cardiac surgery, is associated with significant morbidity and mortality. Pulmonary complications include hypoxemia; increased work of breathing; atelectasis; pneumonia; and in 2% to..
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Abstract Aim To assess the use of (ECPR), compared with manual or mechanical cardiopulmonary resuscitation (CPR), for (OHCA) and in-hospital cardiac arrest (IHCA) in adults and children. Methods The PRISMA guidelines were..
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Abstract We currently perform open-heart procedures using bloodless priming of cardiopulmonary bypass circuits regardless of a patient’s body weight. This study presents results of this blood-saving approach in neonates and..
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Abstract Despite the advantages of extracorporeal membrane oxygenation (ECMO), secondary catheter infection remains a major concern during ECMO support. In this study, to clarify the mechanism of ECMO catheter-related infection, we evaluated the..
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Abstract is associated with impairment of cardiovascular, pulmonary, gastrointestinal, and renal physiology with significant perioperative consequences and has been linked with higher morbidity and mortality after cardiac surgery. Cardiac surgery..
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Abstract Background: Left ventricular (LV) afterload increase with protracted aortic valve (AV) closure may represent a complication of veno-arterial extracorporeal membrane oxygenation (V-A ECMO). The aim of the present study..
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