Abstract Although cardiovascular disease (CVD) is the leading cause of mortality globally, it remains insufficiently understood in large parts of the world. The scientific foundations underpinning CVD risk prediction, diagnostics,..
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Abstract Background: Achieving safe glycemic targets in intensive care remains difficult due to rapidly changing physiology, treatment effects, and measurement noise. Objective: We systematically review artificial-intelligence (AI) methods for ICU..
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Abstract Importance To date, no studies have described the financial burden and behaviors of left ventricular mechanical unloading (LVMU) for patients on veno-arterial extracorporeal membrane oxygenation (VA ECMO). Given the..
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Abstract The ex situ heart perfusion technique is noninferior to the standard of care static cold preservation in heart transplantation. It has enabled the expansion of donor criteria and provides reconditioning or..
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Abstract Background: Minimizing Gaseous microemboli (GME) introduced into the CPB circuit can help alleviate neurologic injury. This study focuses on understanding how suction flow rate and the reservoir level can..
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Abstract Background: The standard method for transporting tissues during limb transplantation and replantation is cold ischemic transport (CIT). However, CIT cannot completely prevent ischemia-reperfusion injury (IRI). As an alternative, extracorporeal..
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Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving intervention for individuals with refractory cardiopulmonary failure and is associated with several complications. Differential hypercapnia, also known as RIDDLER syndrome or..
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Abstract Background: The accuracy and precision of continuous in-line blood gas monitoring (CILBGM) are crucial for optimal blood gas management during cardiopulmonary bypass (CPB) and improved patient outcomes. CILBGM devices,..
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Abstract Objectives To assess the predictive value of early postoperative perfusion markers (central venous oxygen saturation, lactate, and alactic base excess [ABE]) and Sequential Organ Failure Assessment (SOFA) scores in..
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Abstract Objectives The objective of this survey is to assess current practices in anticoagulation management, laboratory monitoring, and hematology involvement in extracorporeal membrane oxygenation (ECMO) patients. Methods A cross-sectional international..
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Abstract Background To gain insight into the role and relevance of inflammatory and immunological markers in the comprehensive assessment of a patient's immune response to surgical procedures. This study focused..
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1. Preoperative Planning & Coordination •Multidisciplinary alignment (cardiac surgery, transplant hepatology, anesthesia, perfusion) •Donor organ assessment and synchronized timing of procurement •Hemodynamic optimization and coagulation planning •blood products (massive..
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Dr.Sam Zeraatian Nejad Davani, Cardiovascular and Transplant surgeon. Advanced Fellow of Thoracic Organs Transplantation Chicago Illinois. ..
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Heterotopic heart transplantation, also known as the “piggyback” or “double heart” transplant, involves implanting a donor heart alongside the recipient’s native heart rather than replacing it. This technique is..
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Il supporto extracorporeo mediante ECMO (Extracorporeal Membrane Oxygenation, ECMO) rappresenta oggi una delle frontiere più complesse e decisive della terapia intensiva, poiché è in grado di fornire un temporaneo..
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Train the Trainers ECMO European edition: the course to prepare ECMO educators to design, deliver, and evaluate high-quality, simulation-based training in accordance with ELSO educational standards, combining sound instructional design,..
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Abstract Perfusionists must maintain strong digital security habits, know the inherent risks of devices in use, and have a healthy respect for the consequences of a security breach at a..
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Abstract Objectives To develop and validate, a real-time algorithm to individualize unfractionated heparin (UFH) dosing based on activated clotting time (ACT) dynamics in cardiac procedures with or without cardiopulmonary bypass..
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Abstract Background: A 17-year-old male patient diagnosed with a single ventricle, in a failed Fontan stage, was evaluated prior to heart transplantation. The patient had a panel-reactive antibody (PRA) for..
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Abstract Background The use of extracorporeal membrane oxygenation (ECMO) has expanded significantly, especially during the COVID-19 pandemic, but membrane lung (ML) function at high altitudes remains unexplored. This study aimed..
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Abstract Background Major bleeding is a common and serious complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO). Current perspectives on bleeding risk fail to reflect dynamic changes over time in..
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Abstract Background and Objective Venoarterial extracorporeal membrane oxygenation (VA ECMO) circuits typically utilise a continuous flow (CF) of blood to support patients suffering from refractory cardiorespiratory dysfunction. Pulsatile flow (PF)..
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Abstract Widely used phthalates, especially di-(2-ethylhexyl) phthalate (DEHP), increase breast cancer risk in experimental animals and humans, but long-term follow-up evidence of its human breast carcinogenicity remains inconclusive. This nested..
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Abstract Objectives Numerous databases exist in the field of cardiac surgery across Europe, but none of them combine the entire captured data of all clinical specialties involved in the care..
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Abstract Despite increasing clinical interest in ambulatory extracorporeal membrane oxygenation (ECMO), its equipment is not optimally designed for portability. Blood pumps are too heavy for ambulation, as the lightest system..
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Abstract Background The prognostic significance of an adverse acid–base milieu despite venoarterial extracorporeal membrane oxygenation support in patients with cardiogenic shock remains poorly defined. We examined metabolic and respiratory disturbances..
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Abstract Goal directed perfusion (GDP) aims to maintain an O2 delivery above 270-300 ml/min/m2, during cardiopulmonary bypass. This strategy decreases the incidence of postoperative acute kidney injury. We first developed a simple..
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Abstract Objectives Enhanced recovery after surgery (ERAS) protocols are patient-centred, interprofessional perioperative care models aimed at reducing hospital stays, complications, healthcare costs, and improving patient satisfaction. Evidence for ERAS in..
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Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) involves cannulation and initiation of venoarterial extracorporeal membrane oxygenation, offering enhanced perfusion during refractory cardiac arrest when conventional cardiopulmonary resuscitation fails. The use of ECPR..
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Abstract Background: Hyperoxia induces oxidative stress and can exacerbate inflammatory response to Veno-Arterial Extracorporeal Life Support (VA–ECLS). This study aimed to evaluate the association between hyperoxia during VA–ECLS and morbidity, complications,..
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