Abstract Factor XII (FXII) is a central mediator at the intersection of coagulation, fibrinolysis, inflammation, and immunity. It is activated upon contact with negatively charged surfaces, triggering the intrinsic coagulation..
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Abstract Anaemia is the term for low red blood cell numbers or a deficiency of hemoglobin, the protein that carries oxygen in red blood cells. This results in a reduction..
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Abstract Myocardial injury is a major predictor of adverse cardiovascular outcomes and is driven by both ischemic and inflammatory mechanisms. Hyperbaric oxygen therapy (HBOT), which delivers 100% oxygen at supra-atmospheric..
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Abstract Objectives Neonates and infants who receive a Ross or Ross-Konno operation form a different population from older children and adults who undergo this procedure. We aimed to provide a..
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Abstract Objective To assess how inclusion criteria from major randomized controlled trials (RCTs) of extracorporeal cardiopulmonary resuscitation (ECPR) apply within a cannulated ECPR cohort and to benchmark observed outcomes against..
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Abstract Extracorporeal membrane oxygenation (ECMO) can trigger a systemic inflammatory response syndrome (SIRS) with activation of inflammatory, endothelial, and coagulation system pathways. We assessed in a randomized trial whether a)..
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Abstract Clinically, the inflammation induced by cardiopulmonary bypass (CPB) is associated with a higher incidence of severe complications and mortality. Based on the absorptive property of hemoperfusion, it has been..
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Abstract Background: Perioperative hyperglycemia is associated with adverse patient outcomes including surgical site infections. This study examined whether an automated insulin dosing reminder is associated with a lower risk for..
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Abstract BACKGROUND: Weaning from cardiopulmonary bypass (CPB) is a critical step in cardiovascular surgery. Although ionized calcium (iCa) plays a crucial role in myocardial contractility, and hypocalcemia commonly occurs during..
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Abstract Background: The clinical differences between intra-aortic balloon pumping (IABP) and a microaxial flow pump (Impella) for left ventricular (LV) unloading in patients with fulminant myocarditis (FM) supported with venoarterial extracorporeal..
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Abstract Background: Heparin is the standard anticoagulant used during cardiopulmonary bypass (CPB). However, there are problems with heparin, including immunogenicity and variability of effect, that make a search for an..
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Abstract Introduction Extracorporeal membrane oxygenation (ECMO) has been used in the care of critically ill neonates since the 1970s. Some neonatal ECMO indications include inadequate tissue oxygen delivery, severe hypoxic..
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Abstract Background: Lactic alkalosis, defined as an increase in circulating lactate in the setting of elevated extracellular pH, has been described in both in vivo and in vitro settings, often..
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Abstract Risk of limb ischemia in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) is minimized with the use of distal perfusion catheters (DPCs). However, conventional sheaths utilize a flow-limiting side..
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Abstract Aims Extracorporeal cardiopulmonary resuscitation (ECPR) can restore circulation in refractory out-of-hospital cardiac arrest (OHCA). A trial-based analysis with a 1-year horizon showed limited cost-effectiveness of this demanding procedure. However,..
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Abstract The past year has yielded important advances in coagulation and transfusion practice across cardiothoracic and vascular care. Patient blood management remains central, with growing evidence supporting restrictive transfusion thresholds,..
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Abstract Background Cardiovascular diseases are the leading cause of mortality worldwide, including in Chile, accounting for about 23% of all deaths. Advanced cardiac surgical procedures like coronary artery bypass grafting..
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Abstract Background Oxygenator oxygen transfer performance is typically measured by manufacturers under standardized, static laboratory conditions. However, these parameters do not adequately reflect the dynamic environment of clinical cardiopulmonary bypass..
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Abstract During cerebral ischemia, the quantitative Electroencephalogram (EEG) Alpha: Delta Ratio (ADR) decreases, and the asymmetry percentage increases. The utility of analyzing these metrics during neonatal Antegrade Cerebral Perfusion (ACP)..
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Special 3 day Rescue Team Course Paris NEXT SESSION 30 November to 2 December 2026 Come learn all you need to know on OHCA, ECPR and REBOA during a 3-day..
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Abstract Weaning and liberation from V-A ECMO for cardiogenic shock involves complex decision-making that requires balancing multiple clinical parameters. In the absence of specific weaning guidelines, ECMO centers rely on..
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Abstract Objectives Hemorrhagic complications remain a major concern in patients with cardiogenic shock and extracorporeal cardiopulmonary resuscitation. The purpose of this study was to assess the effect of withholding a..
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Abstract Background The increasing preference for off-pump coronary artery bypass grafting (CABG) reflects efforts to reduce complications associated with cardiopulmonary bypass (CPB). A lower incidence of postoperative delirium (POD) after..
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Abstract Capnometry is a cost-efficient method of monitoring carbon dioxide (CO2) in healthcare settings, especially during mechanical ventilation and cardiopulmonary bypass. However, the utility of capnometers for studying CO2 elimination in..
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Abstract Background Children with cyanotic congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass (CPB) are exposed to varying oxygenation strategies, and the optimal oxygenation strategy and the impact of..
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Abstract Background The aim of this study is to compare the clinical results of intermittent antegrade and intermittent antegrade/continuous retrograde cardioplegia techniques in patients undergoing cardiac surgery. Methods Between 2023..
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Abstract Background Veno-arterial ExtraCorporeal Membrane Oxygenation (V-A ECMO) as a bridge to recovery or long-term assist devices in severe cardiocirculatory failure typically lasts 5–7 days. There is scarce guidance on..
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Abstract Introduction: Survival after cardiac arrest and prolonged conventional cardiopulmonary resuscitation remains poor, with out-of-hospital survival rates of only 2%–10%. Conventional veno-arterial extracorporeal membrane oxygenation or extracorporeal cardiopulmonary resuscitation can restore..
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Abstract Background: Interest in inhalational anesthesia in cardiac surgery has resurged as volatile anesthetics exert biological effects extending beyond hypnosis. Sevoflurane and desflurane activate mitochondrial cytoprotective signaling pathways, modulate inflammatory..
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Abstract Introduction Mortality in patients receiving Extracorporeal Membrane Oxygenation (ECMO) is partly attributable to unanticipated hemodynamic instability after elective decannulation, termed weaning-related shock (WRS). This study explored the etiology of..
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