Abstract Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion..
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Abstract Differential oxygenation may complicate extracorporeal cardiopulmonary resuscitation (ECPR) either due to the initial pathology or subsequent lung injury. The dual circulation phenomenon inherent to peripheral venoarterial extracorporeal membrane oxygenation..
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Abstract Background Monitoring of unfractionated heparin (UFH) in critically ill patients is challenging due to disease-related alterations of the coagulation system, directly affecting conventional laboratory tests, including activated partial thromboplastin..
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Abstract Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide, with chronic kidney disease (CKD) constituting a significant risk factor. Despite the crucial role of amino acids as fundamental..
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Abstract Introduction Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supports oxygenation and carbon dioxide (CO2) clearance in the short- or mid-term, and is traditionally utilized in severe, refractory respiratory failure. There is..
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Abstract Background Extracorporeal Membrane Oxygenation (ECMO) is a critical rescue therapy complicated by high rates of nosocomial infections (NIs). While Western data abound, evidence from the Middle East remains limited...
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Abstract Antegrade cerebral perfusion (ACP) and hypothermia are widely used neuroprotective strategies during neonatal aortic arch repairs. Still, over 50% of neonates exhibit new or worsened white matter injury in..
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Abstract Acute postoperative bioprosthetic valve thrombosis is a rare complication with challenging treatment. We present two consecutive cases of patients with myocardial infarction and papillary muscle rupture requiring urgent surgical..
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Abstract Introduction Brain infarction (BI) is a severe complication of extracorporeal membrane oxygenation (ECMO) with high morbidity and mortality. We aimed to determine the incidence of BI and identify predictors..
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Abstract Dear Editor, We read with great interest the article by Tanaka et al. reporting their institutional experience with mechanical circulatory support (MCS) in patients undergoing surgical repair of acute..
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Abstract BACKGROUND: Mortality prognostication in adult patients requiring extracorporeal membrane oxygenation (ECMO) is not accurate or established. We hypothesized that composite lactate-based metrics and machine-learning models would improve in-hospital mortality..
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Connect with professionals of today and leaders of tomorrow We’re excited to welcome you to the Beyond Boundaries Meeting in 2026. This is a premier event bringing together leading..
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Abstract Background In order to ensure both surgical safety and reliability, operative management of patients undergoing cardiac surgery requires stringent standards and awareness from cardiac surgeons, anesthesiologists and perfusionists. Among..
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Abstract Introduction: In cardiogenic shock (CS), persistent microcirculatory impairment despite improved macrocirculatory parameters is associated with poor outcomes. Therapeutic strategies must therefore address both macro- and micro-circulation. Conventional microcirculatory measures..
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Abstract Pan and colleagues report the findings of a large, blinded, placebo-controlled single-center randomized clinical trial of sivelestat for the prevention of acute respiratory distress syndrome (ARDS) among patients undergoing..
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Abstract Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..
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Abstract Obesity poses technical challenges during veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannulation because of thick subcutaneous tissue and increased insertion resistance. While patient-related factors are well recognized, the impact of..
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Abstract Introduction Acute kidney injury (AKI) is a well-known serious complication of cardiopulmonary bypass (CPB) surgery and one of the significant risk factors for mortality, prolonged hospital stay, and additional..
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Abstract Restoration of coronary blood flow is essential for myocardial salvage in acute myocardial infarction (AMI), yet substantial injury and adverse remodeling often persist after successful reperfusion. Experimental ischemia–reperfusion models..
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The reversed valved Potts shunt is an advanced surgical strategy for patients with severe Pulmonary Hypertension, designed to create a controlled extracardiac communication between the left pulmonary artery..
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Abstract Although cardiovascular disease (CVD) is the leading cause of mortality globally, it remains insufficiently understood in large parts of the world. The scientific foundations underpinning CVD risk prediction, diagnostics,..
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Abstract Background: Achieving safe glycemic targets in intensive care remains difficult due to rapidly changing physiology, treatment effects, and measurement noise. Objective: We systematically review artificial-intelligence (AI) methods for ICU..
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Abstract Importance To date, no studies have described the financial burden and behaviors of left ventricular mechanical unloading (LVMU) for patients on veno-arterial extracorporeal membrane oxygenation (VA ECMO). Given the..
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Abstract The ex situ heart perfusion technique is noninferior to the standard of care static cold preservation in heart transplantation. It has enabled the expansion of donor criteria and provides reconditioning or..
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Abstract Background: Minimizing Gaseous microemboli (GME) introduced into the CPB circuit can help alleviate neurologic injury. This study focuses on understanding how suction flow rate and the reservoir level can..
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Abstract Background: The standard method for transporting tissues during limb transplantation and replantation is cold ischemic transport (CIT). However, CIT cannot completely prevent ischemia-reperfusion injury (IRI). As an alternative, extracorporeal..
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Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving intervention for individuals with refractory cardiopulmonary failure and is associated with several complications. Differential hypercapnia, also known as RIDDLER syndrome or..
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Abstract Background: The accuracy and precision of continuous in-line blood gas monitoring (CILBGM) are crucial for optimal blood gas management during cardiopulmonary bypass (CPB) and improved patient outcomes. CILBGM devices,..
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Abstract Objectives To assess the predictive value of early postoperative perfusion markers (central venous oxygen saturation, lactate, and alactic base excess [ABE]) and Sequential Organ Failure Assessment (SOFA) scores in..
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Abstract Objectives The objective of this survey is to assess current practices in anticoagulation management, laboratory monitoring, and hematology involvement in extracorporeal membrane oxygenation (ECMO) patients. Methods A cross-sectional international..
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