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Mammalian enteral ventilation ameliorates respiratory failure

Abstract Background Several aquatic organisms such as loaches have evolved unique intestinal breathing mechanisms to survive under extensive hypoxia. To date, it is highly controversial whether such capability can be..

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Understanding the ”Extra-Corporeal Membrane Oxygenation Gap" in Veno-Arterial Configuration for Adult Patients: Timing and Causes of Death

Abstract Objective Timing and causes of hospital mortality in adult patients undergoing veno-arterial extracorporeal membrane oxygenation (V-A ECMO) have been poorly described. Aim of the current review was to investigate..

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The impact of exogenous nitric oxide during cardiopulmonary bypass for cardiac surgery

Abstract Objectives: Cardiac surgery using cardiopulmonary bypass frequently provokes a systemic inflammatory response syndrome. This can lead to the development of low cardiac output syndrome (LCOS). Both of these can..

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O-GlcNAcylation blood levels are increased in response to stress induced by cardiopulmonary bypass

Abstract Introduction Cardiopulmonary bypass (CPB) is a common procedure to maintain body perfusion during cardiac surgery. It is associated with a systemic inflammatory response, hemostasis and circulatory dysfunction that can..

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Randomized Pilot Trial of Acute Normovolemic Hemodilution in Pediatric Cardiac Surgery Patients

Abstract Background: Due to the substantial improvement in survival among pediatric patients undergoing congenital heart surgery, reducing early and long-term morbidity is becoming the major focus of care. Blood transfusion is..

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The assessment of patients undergoing cardiac surgery for Covid-19: Complications occurring during cardiopulmonary bypass

Abstract The outbreak of the novel coronavirus pandemic (COVID-19) has resulted in dramatic changes to the conduct of surgery both from a patient management perspective and in protecting healthcare providers...

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Serum metabolic profile of postoperative acute kidney injury following infant cardiac surgery with cardiopulmonary bypass

Abstract Background We sought to determine differences in the circulating metabolic profile of infants with or without acute kidney injury (AKI) following cardiothoracic surgery with cardiopulmonary bypass (CPB). Methods We..

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Effects of circulatory arrest and cardiopulmonary bypass on cerebral autoregulation in neonatal swine

Abstract Background Cerebral autoregulation mechanisms help maintain adequate cerebral blood flow (CBF) despite changes in cerebral perfusion pressure. Impairment of cerebral autoregulation, during and after cardiopulmonary bypass (CPB), may increase..

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Importance of high-performing teams in the cardiovascular intensive care unit

Abstract The importance of teamwork in health care delivery and patient safety is increasingly being recognized and has benefitted substantially by adopting a human factors' perspective and approach. The scientific..

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Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery

Abstract Objectives:  Cardiopulmonary bypass surgery is complicated by metabolic acidosis, microvascular dysfunction, and capillary leak. The glycocalyx—a layer of proteins and sugars lining the vascular endothelium—is degraded during cardiopulmonary bypass...

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Protamine Test Dose: Impact on Activated Clotting Time and Circuit Integrity

Abstract Background Recurrent observation of clot in the cardiopulmonary bypass circuit after the administration of a protamine test dose (PTD) prompted concern over the effects of PTDs on patient activated..

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Systemic Hypertension in Pediatric Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Systemic hypertension (HTN) is a recognized complication of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in children. We sought to determine the prevalence and associated features of HTN in a..

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Microcirculatory Changes in Pediatric Patients During Congenital Heart Defect Corrective Surgery

Abstract A prospective, observational single-center study was carried out. Pediatric patients undergoing congenital heart defect surgery were evaluated before, during, and after surgery. At each time point, sublingual microcirculation and..

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Directing a dispersion cannula tip toward the aortic root during thoracic aortic arch surgery does not adversely affect cardiac function

Abstract Introduction: Neurologic complications of open thoracic aortic surgery are devastating problems in patients with severely diseased aortas. This study aimed to clarify whether directing the aortic cannula tip toward..

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Scavenging right atrial Bretschneider histidine-tryptophan-ketoglutarate cardioplegia: Impact on hyponatremia and seizures in pediatric cardiac surgery patients

Abstract Objective Custodiol-HTK  (Custodiol-HTK Koheler Chemie, GmbH, Bensheim, Germany) causes fluctuations in serum sodium levels, , and is associated with postoperative seizures. We investigated the influence of scavenging right atrial effluent during..

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Initial experience with del Nido cardioplegia solution at a Pediatric and Congenital Cardiac Surgery Program in Brazil

Abstract Objective: The aim of this study was to evaluate outcome measures between our standard multidose cardioplegia protocol and a del Nido cardioplegia protocol in congenital heart surgery patients. Methods:..

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Fluid Status After Cardiac Surgery Assessed by Bioelectrical Impedance Vector Analysis and the Effects of Extracorporeal Circulation

Abstract Objective  after cardiac surgery can be difficult to assess, often requiring invasive measurements. Bioelectrical impedance vector analysis (BIVA) is based on patterns of resistance (R) and reactance (Xc), corrected..

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Influence of cardiopulmonary bypass set-up and management on clinical outcomes after minimally invasive aortic valve surgery

Abstract Introduction: Minimally invasive aortic valve replacement (MIAVR) requires changes in cannulation strategy and cardiopulmonary bypass (CPB) management when compared to the conventional approach (CAVR). We aimed at evaluating if..

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FISIOLOGIA CARDÍACA - Webinar 12

Aula sobre fisiologia cardíaca. A nossa primeira aula de uma série para falar do coração. Prof. Elio Carvalho é Biomédico, Microbiologista e Perfusionista pela Unicamp, CLAP e SBCEC. É perfusionista..

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Right pulmonary artery (RPA) stenosis

Pulmonary artery stenosis is a heart defect that causes a narrowing of the pulmonary artery, the large blood vessel that takes blood from the right ventricle of the heart to..

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Tricuspid valve stenosis

Very little is known about tricuspid valve when compared to other valves, and tricuspid stenosis is rarely described. It most often co-exists with mitral valve pathology especially in patients with..

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Uhl anomaly

Uhl's Anomaly is a rare cardiac condition in which there is total absence of right ventricular myocardium resulting in apposition of the endocardium and epicardium. We report a case of..

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Turner syndrome

Turner syndrome, a condition that affects only females, results when one of the X chromosomes (sex chromosomes) is missing or partially missing. Turner syndrome can cause a variety of medical..

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Single ventricle

A single ventricle is an uncommon occurrence in embryogenesis, which results in the anatomical or functional loss of a ventricular cavity. These malformations are life-threatening and necessitate quick revision to..

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Shone Syndrome

Shone syndrome is a collection of eight left-sided obstructive heart lesions. These affect blood flow to and from the left ventricle, or lower left heart chamber. Shone syndrome was identified..

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Right cervical arch

Cervical aortic arches are a rare  characterized by an elongated, high-lying aortic arch extending at or above the level of the medial ends of the .

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Right aortic arch

Right aortic arch anomalies occur in approximately 0.01 to 0.1 percent of the general population. In general, these anomalies do not directly cause any cardiovascular problems. However, in some patients,..

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Retroesophagial aortic arch

Right aortic arch is an uncommon anatomic anomaly, which occurs in approximately 0.05% to 0.1% of the population. “Mirror-image” right aortic arch is by itself generally asymptomatic, but it is usually..

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