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Pragmatic Assessment of VA-ECMO Decannulation Readiness After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract Background Readiness for venoarterial-extracorporeal membrane oxygenation (VA-ECMO) decannulation after extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) remains poorly defined. Objectives The objective of the study was to..

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Partial carina resection, reconstruction, and left pneumonectomy under median sternotomy combined with cardiopulmonary bypass: a case report

Abstract Background There is limited clinical data to guide surgical decisions for ACC with extensive carinal involvement in the left main bronchus. In this case, it is shown that median..

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Brain Death Determination During VA-ECMO After Pediatric Cardiac Surgery: A Case-Based Analysis of the 2023 Unified Consensus

Abstract Background Determination of brain death/death by neurologic criteria (BD/DNC) in patients supported with extracorporeal membrane oxygenation (ECMO) is particularly challenging due to extracorporeal carbon dioxide clearance, which may interfere..

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Transseptal Access System-Assisted Atrial Flow Regulator Implantation for Pediatric Left Ventricular Decompression During VA-ECMO

Abstract Left ventricular (LV) overload is a recognized complication of venoarterial extracorporeal membrane oxygenation (VA-ECMO), but pediatric decompression remains technically challenging and poorly standardized. The atrial flow regulator (AFR) (Occlutech) is..

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Extracorporeal Membrane Oxygenation Ethics

Abstract Topic Importance Extracorporeal membrane oxygenation (ECMO) is a relatively novel, intensive medical intervention. It is known to raise important yet unsettled ethical concerns. Overview We established the ECMO Ethics..

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Silent cerebral infarction after proximal thoracic aortic surgery under deep hypothermic circulatory arrest: an exploratory prospective DW-MRI study

Abstract Background Deep hypothermic circulatory arrest (DHCA) is widely used in proximal thoracic aortic surgery; however, its association with subclinical cerebral ischemic changes remains poorly understood. Diffusion-weighted magnetic resonance imaging..

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A Novel Method for Predicting Recirculation by Sweep-Gas Control in Extracorporeal Membrane Oxygenation

Abstract Purpose: Recirculation is a critical issue in veno-venous extracorporeal membrane oxygenation (VV ECMO). We propose a novel method for estimating the recirculation ratio using temporary sweep-gas control. Methods: A circuit simulating..

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2026 SEECMO Summit Series 2 - Webinar: Hemolysis - Sept 1

Hemolysis in ECMO: More Than Just a Laboratory Finding   Hemolysis remains one of the most challenging complications during ECMO support, impacting patient outcomes, circuit performance, and multidisciplinary decision-making. Understanding..

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BACK TO LIFE - Dec 4/6

Hayatı Geri Getirmek Bir Ekip İşidir Her yıl milyonlarca insan ani kardiyak arrest, ağır travma, şok ve kritik hastalık nedeniyle yaşam mücadelesi veriyor. Bugün biliyoruz ki başarılı resüsitasyon; tek bir..

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The MAMBO Framework and the Future of Modern Perfusion: Artificial Intelligence, Cognitive Ergonomics, and Sustainable Workflow Integration

Abstract Artificial intelligence (AI), predictive analytics, and digital health technologies are progressively reshaping extracorporeal circulation and perioperative cardiovascular care. In this evolving landscape, cardiopulmonary bypass management is transitioning from a..

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The Role of Recirculation-Guided Blood Flow Adjustment in Venovenous Extracorporeal Membrane Oxygenation: A Pilot Study

Abstract Recirculation reduces the efficiency of venovenous extracorporeal membrane oxygenation (V-V ECMO), but patient-specific determinants of recirculation and the feasibility of recirculation-guided flow adjustment are not well defined. In this..

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Laboratory Monitoring Unfractionated Heparin Treatments: Unanswered Issues

Abstract Unfractionated heparin (UFH) has long been an anticoagulant of choice. Despite the increasing use of low molecular weight heparin derivatives and more recently direct oral anticoagulants, UFH is still..

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Sevoflurane diffusion across four paediatric cardiopulmonary bypass oxygenators: a laboratory investigation

Abstract In children, validated tools to monitor anaesthetic depth are lacking. In routine practice, dosing of volatile agents relies on surrogate markers such as minimum alveolar concentration and autonomic responses. In..

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The association of estimated citrate load with frozen plasma versus four-factor prothrombin complex concentrate for coagulopathy after cardiac surgery: a…

Abstract Background Frozen plasma (FP) is the standard haemostatic therapy after cardiopulmonary bypass, but recent trials indicate that FP is inferior to four-factor prothrombin complex concentrate (PCC). Citrate content may..

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How I do it Creating a Program for Neurologic Prognostication after Cardiac Arrest

Abstract Multimodal neurologic prognostication (MM-NP) after cardiac arrest has been shown to enhance prognostic accuracy, however, it is vastly underutilized in real-world settings. Guideline-discordant practices and healthcare disparities in post-cardiac..

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Sex-Related Long-Term Outcomes in On-Pump Coronary Artery Bypass Grafting—A Propensity Score-Matched Analysis

Abstract Objectives Coronary artery bypass grafting shows impaired outcomes in women compared to men. Investigation of sex-related outcome differences mostly comprises different operative strategies, potentially hampering interpretation of data. We..

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Neonatal enterovirus myocarditis outcomes following extracorporeal membrane oxygenation (NEMO-ECMO): An ELSO registry analysis

Abstract Background Neonates with enterovirus myocarditis may require extracorporeal membrane oxygenation (ECMO). The contemporary prognosis and risk factors for mortality of neonates with enterovirus myocarditis supported on ECMO is unknown...

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Feasibility and safety of a novel activated leukocyte adsorption device during cardiopulmonary bypass: a first-in-human pilot study

Abstract Cardiopulmonary bypass (CPB) induces inflammation partly via leukocyte activation. We conducted a first-in-human pilot study assessing the feasibility and perioperative safety of a novel activated leukocyte adsorption device during..

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Real-time cardiac power output index predicts imminent need for extracorporeal membrane oxygenation after heart transplantation

Abstract Background Primary graft dysfunction (PGD) remains the leading cause of early morbidity and mortality after heart transplantation. Despite consensus definitions, clinicians still rely on subjective, indirect assessments of graft..

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Fluid balance during PICU stay in children after cardiac surgery with cardiopulmonary bypass

Abstract Background Pediatric patients undergoing cardiac surgery are at risk for developing positive cumulative fluid balance (CFB). Our goal was to study postoperative CFB in this population, its explanatory variables,..

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Levosimendan for Weaning from VA-ECMO: Two Trials, Two Timings

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for providing adequate organ support in cardiogenic shock. While the intervention provides circulatory and respiratory support in the critical stage, it..

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Extracorporeal Life Support Use During Severe Anaphylaxis: A Systematic Review and Pooled Analysis of Individual Patient Data

Abstract Objective Severe anaphylaxis is a rare but life-threatening condition that may require extracorporeal life support (ECLS). A systematic review was conducted to evaluate the outcomes of patients receiving ECLS..

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Head–core temperature discordance during hypothermic circulatory arrest in acute type A aortic dissection

Abstract Objectives Core temperature is routinely used to guide hypothermic circulatory arrest (HCA) for acute type A aortic dissection (ATAAD). However, it remains unclear whether impaired carotid artery flow alters..

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Clinical Effectiveness of Acute Normovolemic Hemodilution in Cardiac Surgery: A Systematic Review and Meta-analysis

Abstract BACKGROUND: Acute normovolemic hemodilution (ANH) is endorsed by contemporary patient blood management guidelines as a cost-effective strategy for reducing allogeneic transfusion in cardiac surgery. However, evidence remains inconsistent due..

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Mortality-related predictors in patients receiving extracorporeal membrane oxygenation after coronary artery bypass grafting: a retrospective study

Abstract Background This study aimed to evaluate in-hospital mortality and to identify predictors of mortality in coronary artery bypass grafting (CABG) patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. Methods..

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Long-term psychological outcomes after extracorporeal membrane oxygenation: A systematic review and meta-analysis

Abstract Background Use of extracorporeal membrane oxygenation (ECMO) for cardiorespiratory failure has increased substantially. While long-term outcomes for psychological health are increasingly assessed and addressed in critical care survivorship research,..

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Comparison of clinical outcomes between pulsatile and non-pulsatile perfusion during cardiopulmonary bypass: A prospective randomized study

Abstract Background: The clinical benefits of pulsatile perfusion during cardiopulmonary bypass (CPB) remain a subject of debate. This study aimed to compare clinical outcomes between pulsatile and non-pulsatile perfusion during..

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Heparin Dose-Response Curve for Heparin Dose Determination During Cardiopulmonary Bypass for Pediatric Cardiac Surgery: A Prospective Randomized Controlled Study

Abstract Objectives To determine whether individualized heparin dosing guided by a heparin dose-response (HDR) curve is noninferior to conventional weight-based dosing in achieving target activated clotting time (ACT) of ≥480..

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Extracorporeal membrane oxygenation initiation timing and prognosis: a systematic review and meta-analysis

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical life-support intervention for patients with severe respiratory and circulatory failure. Nevertheless, identifying the optimal timing of ECMO initiation and its correlation..

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Extracorporeal Membrane Oxygenation Prior to Death: Standardized Terminology for ECMO-Supported Organ Donation Pathways

Abstract The expanding use of extracorporeal cardiopulmonary resuscitation (ECPR) has introduced new clinical scenarios at the intersection of extracorporeal life support and organ donation. Current donor classification systems do not..

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