Abstract Background Laboratory research suggests that vasopressin restores systemic arterial pressure without significantly increasing pulmonary artery pressures, compared with norepinephrine. We therefore tested the hypotheses that treatment of intraoperative vasoplegia..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized in critical care globally to allow for adequate oxygenation in patients with cardiac and/or respiratory failure. Unfortunately, haemostatic complications – both..
Read MoreAbstract Background The Extracorporeal Life Support Organization recommends daily antithrombin monitoring and supplementation to achieve > 50%–80% activity during extracorporeal membrane oxygenation (ECMO). Evidence supporting this practice is uncertain, and whether..
Read MoreAbstract Background The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions in anaemic patients remains an active area of research. Blood is a limited resource, and there..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is now commonly used to manage refractory pediatric cardiac or respiratory failure. Traditionally, ECMO has been associated with high morbidity. However, despite advancements in ECMO..
Read MoreAbstract ECPR Efficacy and Use: Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival and neurologic outcomes in refractory out-of-hospital cardiac arrest, with global adoption and center availability expanding significantly.
Read MoreAbstract Purpose The benefits of adopting restrictive transfusion strategies, as opposed to a liberal approach, during extracorporeal membrane oxygenation (ECMO) remain unclear. This network meta-analysis aims to determine whether a..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) can cause blood water loss due to insensible perspiration via oxygenators and plasma leakage. The accurate quantification of water loss is crucial for maintaining..
Read MoreAbstract BACKGROUND Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at risk for peri-operative complications, often linked to endothelial dysfunction. The Endothelial Activation and Stress Index (EASIX) has shown..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (eCPR) is a highly resource-intensive procedure, and its cost-effectiveness remains a subject of debate []. Hospital-based eCPR for refractory out-of-hospital cardiac arrest has been shown to..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) can provide an option for high-risk procedures that may result in cardiopulmonary collapse. The indications for ECMO standby are not well delineated. We describe the..
Read MoreAbstract Background Children undergoing extracorporeal membrane oxygenation (ECMO) are at risk of hematologic and coagulation complications, including intracranial hemorrhage. Thromboelastography is used to monitor anticoagulation in patients receiving ECMO, but..
Read MoreAbstract Objectives Minimal invasive Extracorporeal Circulation (MiECC) and Hybrid System (HS) have been introduced to potentially reduce the inflammatory response compared to conventional Cardiopulmonary Bypass (cCPB). The HS combines elements..
Read MoreAbstract Importance Postoperative red blood cell transfusion guidelines recommend transfusion for hemoglobin levels less than 7 g/dL. However, the safety of this strategy in patients at high risk of cardiac events..
Read MoreAbstract Immediate recognition of cardiac arrest and the initiation of cardiopulmonary resuscitation (CPR) can significantly improve survival chances. The use of extracorporeal membrane oxygenation during CPR (eCPR) could further enhance..
Read MoreAbstract Aim To characterize the impact of BMI (body mass index) on HIBI (hypoxic-ischemic brain injury) in patients receiving ECPR, with the hypothesis that elevated BMI is associated with increased..
Read MoreAbstract Background Heart transplantation remains the gold standard for the treatment of end-stage heart failure, but severe pulmonary hypertension (PH) poses a significant challenge due to the increased risk of..
Read MoreAbstract Background: Surgical site infections are the second most common type of healthcare-associated infection. Objective: This study aimed to assess the incidence and associated risk factors of surgical site infection..
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), involving VA-ECMO during refractory cardiac arrest, has been linked to improved outcomes. While systemic anticoagulation is commonly used to prevent circuit thrombosis, bleeding and..
Read MoreAbstract Objectives: Decannulation after pediatric extracorporeal life support (ECLS) may be accompanied by arterial reconstruction. There is a paucity of data on arterial morphology following reconstruction. We sought to characterize..
Read MoreAbstract Background Smart digital technologies are rapidly transforming perioperative care through tools such as clinical decision support systems, wearable sensors, and electronic checklists. Despite growing adoption, their specific impact on..
Read MoreAbstract Treating severe lung diseases with extracorporeal membrane oxygenation (ECMO) is often accompanied by serious complications, restricting applicability and adversely affecting outcomes. Membrane oxygenators, based on hollow fiber membranes (HFM),..
Read MoreAbstract Introduction Heparin is usually added to infant cardiopulmonary bypass circuit primes. Ultrafiltration is often used to minimise prime volume before commencing bypass. The extent of heparin removal from bypass..
Read MoreAbstract This study focuses on the impact of virtual reality (VR) technologies on educational processes and professional training, particularly in the fields of medicine, aviation, and the arts. The purpose..
Read MoreAbstract Objectives: An increasing number of pediatric centers use the femoral vein in neonates and smaller children to provide venovenous multisite (VVMS) extracorporeal membrane oxygenation (ECMO), but there are no..
Read MoreAbstract Objectives: Limited data exist on outcomes in COVID-19- vs. influenza A (H1N1)-associated acute respiratory distress syndrome (ARDS) patients when supported on venovenous extracorporeal membrane oxygenation (ECMO). We aimed to..
Read MoreAbstract The optimal arterial cannulation site in minimally invasive cardiac surgery (MICS) remains debated. While axillary, femoral, and central approaches each offer distinct advantages, no prior network meta-analysis has compared..
Read MoreAbstract Invasive cases of Mycobacterium chimaera have been found in Europe, and beyond, and have been associated with the use of heater–cooler units necessary to regulate the temperature of blood in extracorporeal..
Read MoreAbstract Thrombosis and inflammation represent major challenges limiting the functionality of asymmetric poly(4-methyl-1-pentene) (PMP) hollow fiber membranes in extracorporeal membrane oxygenation (ECMO) systems. Moreover, the interplay between these two pathological..
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