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Damage-Associated Molecular Patterns in Perioperative Anesthesia Care: A Clinical Perspective

Abstract Damage-associated molecular patterns (DAMPs) are endogenous molecules released during cellular stress or injury that trigger sterile inflammation. In perioperative settings, common triggers include surgical trauma, ischemia–reperfusion injury, cardiopulmonary bypass,..

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Custodial-HTK Cardioplegia in Conventional Cardiac Surgery: A Retrospective Analysis From UiTM

Abstract Myocardial protection remains one of the most critical determinants of success in cardiac surgery, particularly during prolonged ischemic periods associated with cardiopulmonary bypass and aortic cross-clamping. The article Custodial-HTK..

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Extracorporeal Membrane Oxygenation Discontinuation Due to Resource Limitations

Abstract To examine the global epidemiology of extracorporeal membrane oxygenation discontinuation due to resource limitation (EDRL), assessing differences across geographic regions and between pre- and post-coronavirus disease 2019 (COVID-19) periods...

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Challenges of ECMO use for severe trauma: a narrative review

Abstract Background Patients with severe trauma are at high risk of developing life-threatening complications, including acute respiratory failure and circulatory collapse. Extracorporeal membrane oxygenation (ECMO) offers critical support when conventional..

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Ultrasound in Extracorporeal Membrane Oxygenation: An ELSO State-of-the-Art Review

Abstract Ultrasound has become indispensable in the management of patients supported with extracorporeal membrane oxygenation (ECMO), enabling rapid diagnosis, procedural guidance, physiologic monitoring, and informed decision-making across the entire ECMO..

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Predictive Power of the Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion Score for Cardiac Surgery–Associated Acute Kidney Injury:…

Abstract Objectives The Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion (ACTA-PORT) score was originally developed to predict the need for transfusion in cardiac surgery patients. Given the inter-relationship..

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When stopping is just as important as starting: the challenge of extracorporeal membrane oxygenation

Abstract Extracorporeal life support (ECLS) is a high-risk, high-cost intervention that often entails prolonged ICU and hospital stays. Its rapid evolution raises crucial questions of appropriateness, proportionality, and value. Whereas..

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Early mechanical reperfusion in high-risk pulmonary embolism supported by V-A ECMO: a multicenter international cohort study

Abstract Objectives To explore how early mechanical reperfusion impacts outcomes in high-risk pulmonary embolism (PE) patients supported by veno-arterial extracorporeal membrane oxygenation (V-A ECMO). Methods This retrospective international study included..

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Bridge to transplant using a flow-adaptive extracorporeal total artificial lung system following bilateral pneumonectomy

Abstract Background Severe acute respiratory distress syndrome (ARDS) complicated by necrotizing pneumonia and septic shock carries a mortality exceeding 80%. Lung transplantation is rarely pursued because persistent sepsis, uncertainty regarding..

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Consciousness and Controlled Donation After Circulatory Determination of Death

Abstract A recent series of near-misses in which patients scheduled for organ recovery exhibited unexpected signs of consciousness recognized only moments before initiation of surgery has triggered investigations by national bodies. In September 2024, a..

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Ultrafiltration in the critically ill patient: a framework for personalized care

Abstract Fluid overload is common after resuscitation in critically ill patients and is independently associated with unfavorable outcomes. Ultrafiltration (UF) during renal replacement therapy is a common strategy to reverse..

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Death by Neurologic Criteria in Neonates Undergoing Extracorporeal Membrane Oxygenation: Extracorporeal Life Support Organization Registry Study, 2010–2023

Abstract Objectives:  To identify factors associated with the development of death by neurologic criteria (DNC) in neonates treated with extracorporeal membrane oxygenation (ECMO). Design:  Retrospective registry study. Setting:  Data reported..

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Mortality and complications in low-dose vs standard-dose unfractionated heparin anticoagulation for extracorporeal membrane oxygenation: a systematic review and meta-analysis

Abstract Background Controversies exist in anticoagulation practices in extracorporeal membrane oxygenation (ECMO). It is uncertain whether the intensity of anticoagulation affects ECMO outcomes. Objectives To conduct a meta-analysis to determine..

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Preoperative Extracorporeal Membrane Oxygenation in Children With Dextro-Transposition of the Great Arteries: Extracorporeal Life Support Organization Registry Study, 2000–2022

Abstract Objective:  To describe those neonates with dextro-transposition of the great arteries (d-TGA) who undergo preoperative support with extracorporeal membrane oxygenation (ECMO) and to compare outcomes in those undergoing the..

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ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation

Abstract The number of potential pediatric heart transplant recipients continues to exceed the number of donors, and consequently the waitlist mortality remains significant. Despite this, around 40% of all donated..

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Alternative Base Solutions for del Nido Cardioplegia: Composition, Rationale, and Clinical Evidence

Abstract Objectives Del Nido cardioplegia has gained increasing popularity, evolving from its original use in paediatric and congenital heart surgery to widespread adoption in adult cardiac procedures. This review aims..

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Conversion From Venovenous to Venoarterial or Hybrid Extracorporeal Membrane Oxygenation: Analysis From the Extracorporeal Life Support Organization Registry

Abstract Objectives:  Venovenous extracorporeal membrane oxygenation (ECMO) represents a standard and well-accepted modality of treating patients with refractory respiratory failure. Nevertheless, some patients might develop refractory hypoxemia, hemodynamic compromise or..

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Impact of Peak Donor Troponin and Donor Troponin Trends on Pediatric Heart Transplant Outcomes

Abstract Background Donor discard rates for pediatric heart transplant (HT) remain high (≈40%), often driven by concerns about elevated donor troponin levels. This study evaluated the association between peak donor..

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Barts Summer ECMO Course 2026 - 19/21 June

Date:  Friday, 19-Jun-2026 to Sunday, 21-Jun-2026   Duration(Days):  3  Accreditation :  15 CPD points - RCOA Availability: Available   Location : West Wing Conference Centre, London, England, EC1A 7BE   Contact email:  Fee options:  Consultant or..

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ECMO in Out-of-Hospital Cardiac Arrest

ECMO in Out-of-Hospital Cardiac Arrest: A Matter of Time and Details - ECMO en la parada cardiaca extrahospitalaria: una cuestión de tiempo y detalles This EuroELSO webinar is organized together..

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Effect of prone positioning on pathophysiology and lung histopathology during VV-ECMO in severe ARDS: an experimental animal study

Abstract Background: Prone positioning improves survival in patients with acute respiratory distress syndrome (ARDS) by reducing ventilator-induced lung injury and enhancing ventilation–perfusion matching. Whether these physiological benefits translate to patients..

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Investigating biomarkers associated with mortality in patients receiving VA-ECMO for cardiogenic shock: a systematic review

Abstract Context: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-sustaining therapy for severe refractory cardiogenic shock. Although VA-ECMO provides various degrees of cardiopulmonary support, mortality rates remain high. Serum biomarkers have..

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Perfusionist’s role in long-term ventricular assist device

Abstract Introduction Ventricular assist devices (VADs) have emerged as essential tools for stage D heart failure, improving survival and quality of life by serving as a bridge to transplant, destination..

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Dioxygen consumption after deep hypothermic circulatory arrest pulmonary endarterectomy

Abstract Objectives Cardiac surgery is associated with an increased dioxygen (O2) consumption (VO2) following cardiopulmonary bypass (CPB). But data on intraoperative VO2 variation during pulmonary endarterectomy (PEA) are scarce. We aimed..

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Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation: Insights From the SAVE-J II Study

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), an emerging resuscitative therapy following refractory cardiac arrests, is associated with hemorrhagic complications that potentially affect patient outcomes. Objectives This study evaluated the risks..

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Pediatric venoarterial and venovenous ECMO

Abstract  (ECMO) is an invaluable resource in the treatment of critically ill children with cardiopulmonary failure.  To date, over 36,000 children have been placed on ECMO and the utilization of..

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A consensus of international experts on definition, sampling, treatment, and prevention of peripheral extracorporeal membrane oxygenation cannula-site infection obtained by…

Abstract Background: Nosocomial infections are common in patients receiving extracorporeal membrane oxygenation (ECMO), with ECMO cannula‑site infections (ECMO‑CSI) being the most frequent infections directly related to the ECMO run. These..

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Cell salvage in bacterially contaminated surgical fields – A scoping review

Abstract Objective This scoping review systematically examines the use of intraoperative cell salvage in bacterially contaminated surgical settings, examining contamination levels, decontamination strategies, and clinical outcomes following the reinfusion of..

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The importance of early veno-arterial extracorporeal membrane oxygenation in the management of amniotic fluid embolism complicated by cardiac arrest: a…

Abstract Background Amniotic fluid embolism (AFE) with cardiac arrest is an obstetric emergency with an exceedingly high maternal mortality. Early application of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may provide essential..

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Mechanisms of immune modulation by therapeutic plasma exchange

Abstract Therapeutic plasma exchange (TPE) is a cornerstone extracorporeal therapy with broad immunomodulatory effects across diverse immune-mediated and inflammatory diseases. By removing circulating pathogenic substances such as autoantibodies, immune complexes,..

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